Dynamical Models in Biology

Dynamical Models in Biology PDF Author: Miklós Farkas
Publisher: Academic Press
ISBN: 0080530605
Category : Mathematics
Languages : en
Pages : 199

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Book Description
Dynamic Models in Biology offers an introduction to modern mathematical biology. This book provides a short introduction to modern mathematical methods in modeling dynamical phenomena and treats the broad topics of population dynamics, epidemiology, evolution, immunology, morphogenesis, and pattern formation. Primarily employing differential equations, the author presents accessible descriptions of difficult mathematical models. Recent mathematical results are included, but the author's presentation gives intuitive meaning to all the main formulae. Besides mathematicians who want to get acquainted with this relatively new field of applications, this book is useful for physicians, biologists, agricultural engineers, and environmentalists. Key Topics Include: - Chaotic dynamics of populations - The spread of sexually transmitted diseases - Problems of the origin of life - Models of immunology - Formation of animal hide patterns - The intuitive meaning of mathematical formulae explained with many figures - Applying new mathematical results in modeling biological phenomena Miklos Farkas is a professor at Budapest University of Technology where he has researched and instructed mathematics for over thirty years. He has taught at universities in the former Soviet Union, Canada, Australia, Venezuela, Nigeria, India, and Columbia. Prof. Farkas received the 1999 Bolyai Award of the Hungarian Academy of Science and the 2001 Albert Szentgyorgyi Award of the Hungarian Ministry of Education. - A 'down-to-earth' introduction to the growing field of modern mathematical biology - Also includes appendices which provide background material that goes beyond advanced calculus and linear algebra

Dynamical Models in Biology

Dynamical Models in Biology PDF Author: Miklós Farkas
Publisher: Academic Press
ISBN: 0080530605
Category : Mathematics
Languages : en
Pages : 199

Get Book Here

Book Description
Dynamic Models in Biology offers an introduction to modern mathematical biology. This book provides a short introduction to modern mathematical methods in modeling dynamical phenomena and treats the broad topics of population dynamics, epidemiology, evolution, immunology, morphogenesis, and pattern formation. Primarily employing differential equations, the author presents accessible descriptions of difficult mathematical models. Recent mathematical results are included, but the author's presentation gives intuitive meaning to all the main formulae. Besides mathematicians who want to get acquainted with this relatively new field of applications, this book is useful for physicians, biologists, agricultural engineers, and environmentalists. Key Topics Include: - Chaotic dynamics of populations - The spread of sexually transmitted diseases - Problems of the origin of life - Models of immunology - Formation of animal hide patterns - The intuitive meaning of mathematical formulae explained with many figures - Applying new mathematical results in modeling biological phenomena Miklos Farkas is a professor at Budapest University of Technology where he has researched and instructed mathematics for over thirty years. He has taught at universities in the former Soviet Union, Canada, Australia, Venezuela, Nigeria, India, and Columbia. Prof. Farkas received the 1999 Bolyai Award of the Hungarian Academy of Science and the 2001 Albert Szentgyorgyi Award of the Hungarian Ministry of Education. - A 'down-to-earth' introduction to the growing field of modern mathematical biology - Also includes appendices which provide background material that goes beyond advanced calculus and linear algebra

Dynamic Models in Biology

Dynamic Models in Biology PDF Author: Stephen P. Ellner
Publisher: Princeton University Press
ISBN: 1400840961
Category : Science
Languages : en
Pages : 352

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Book Description
From controlling disease outbreaks to predicting heart attacks, dynamic models are increasingly crucial for understanding biological processes. Many universities are starting undergraduate programs in computational biology to introduce students to this rapidly growing field. In Dynamic Models in Biology, the first text on dynamic models specifically written for undergraduate students in the biological sciences, ecologist Stephen Ellner and mathematician John Guckenheimer teach students how to understand, build, and use dynamic models in biology. Developed from a course taught by Ellner and Guckenheimer at Cornell University, the book is organized around biological applications, with mathematics and computing developed through case studies at the molecular, cellular, and population levels. The authors cover both simple analytic models--the sort usually found in mathematical biology texts--and the complex computational models now used by both biologists and mathematicians. Linked to a Web site with computer-lab materials and exercises, Dynamic Models in Biology is a major new introduction to dynamic models for students in the biological sciences, mathematics, and engineering.

Dynamical Systems in Population Biology

Dynamical Systems in Population Biology PDF Author: Xiao-Qiang Zhao
Publisher: Springer Science & Business Media
ISBN: 0387217614
Category : Mathematics
Languages : en
Pages : 285

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Book Description
Population dynamics is an important subject in mathematical biology. A cen tral problem is to study the long-term behavior of modeling systems. Most of these systems are governed by various evolutionary equations such as difference, ordinary, functional, and partial differential equations (see, e. g. , [165, 142, 218, 119, 55]). As we know, interactive populations often live in a fluctuating environment. For example, physical environmental conditions such as temperature and humidity and the availability of food, water, and other resources usually vary in time with seasonal or daily variations. Therefore, more realistic models should be nonautonomous systems. In particular, if the data in a model are periodic functions of time with commensurate period, a periodic system arises; if these periodic functions have different (minimal) periods, we get an almost periodic system. The existing reference books, from the dynamical systems point of view, mainly focus on autonomous biological systems. The book of Hess [106J is an excellent reference for periodic parabolic boundary value problems with applications to population dynamics. Since the publication of this book there have been extensive investigations on periodic, asymptotically periodic, almost periodic, and even general nonautonomous biological systems, which in turn have motivated further development of the theory of dynamical systems. In order to explain the dynamical systems approach to periodic population problems, let us consider, as an illustration, two species periodic competitive systems dUI dt = !I(t,Ul,U2), (0.

The Dynamics of Biological Systems

The Dynamics of Biological Systems PDF Author: Arianna Bianchi
Publisher: Springer Nature
ISBN: 3030225836
Category : Mathematics
Languages : en
Pages : 278

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Book Description
The book presents nine mini-courses from a summer school, Dynamics of Biological Systems, held at the University of Alberta in 2016, as part of the prestigious seminar series: Séminaire de Mathématiques Supérieures (SMS). It includes new and significant contributions in the field of Dynamical Systems and their applications in Biology, Ecology, and Medicine. The chapters of this book cover a wide range of mathematical methods and biological applications. They - explain the process of mathematical modelling of biological systems with many examples, - introduce advanced methods from dynamical systems theory, - present many examples of the use of mathematical modelling to gain biological insight - discuss innovative methods for the analysis of biological processes, - contain extensive lists of references, which allow interested readers to continue the research on their own. Integrating the theory of dynamical systems with biological modelling, the book will appeal to researchers and graduate students in Applied Mathematics and Life Sciences.

Modeling Life

Modeling Life PDF Author: Alan Garfinkel
Publisher: Springer
ISBN: 3319597310
Category : Mathematics
Languages : en
Pages : 456

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Book Description
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of early-stage undergraduates, thus providing a practical alternative to the procedural approach of a traditional Calculus curriculum. Tools are developed within numerous, relevant examples, with an emphasis on the construction, evaluation, and interpretation of mathematical models throughout. Encountering these concepts in context, students learn not only quantitative techniques, but how to bridge between biological and mathematical ways of thinking. Examples range broadly, exploring the dynamics of neurons and the immune system, through to population dynamics and the Google PageRank algorithm. Each scenario relies only on an interest in the natural world; no biological expertise is assumed of student or instructor. Building on a single prerequisite of Precalculus, the book suits a two-quarter sequence for first or second year undergraduates, and meets the mathematical requirements of medical school entry. The later material provides opportunities for more advanced students in both mathematics and life sciences to revisit theoretical knowledge in a rich, real-world framework. In all cases, the focus is clear: how does the math help us understand the science?

Stochastic Dynamics for Systems Biology

Stochastic Dynamics for Systems Biology PDF Author: Christian Mazza
Publisher: CRC Press
ISBN: 1466514949
Category : Mathematics
Languages : en
Pages : 272

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Book Description
This is one of the first books to provide a systematic study of the many stochastic models used in systems biology. The book shows how the mathematical models are used as technical tools for simulating biological processes and how the models lead to conceptual insights on the functioning of the cellular processing system. Examples cover the phage lambda genetic switch, eukaryotic gene expression, noise propagation in gene networks, and more. Most of the text should be accessible to scientists with basic knowledge in calculus and probability theory.

Dynamic Modeling in Behavioral Ecology

Dynamic Modeling in Behavioral Ecology PDF Author: Marc Mangel
Publisher: Princeton University Press
ISBN: 9780691085067
Category : Science
Languages : en
Pages : 328

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Book Description
This book describes a powerful and flexible technique for the modeling of behavior, based on evolutionary principles. The technique employs stochastic dynamic programming and permits the analysis of behavioral adaptations wherein organisms respond to changes in their environment and in their own current physiological state. Models can be constructed to reflect sequential decisions concerned simultaneously with foraging, reproduction, predator avoidance, and other activities. The authors show how to construct and use dynamic behavioral models. Part I covers the mathematical background and computer programming, and then uses a paradigm of foraging under risk of predation to exemplify the general modeling technique. Part II consists of five "applied" chapters illustrating the scope of the dynamic modeling approach. They treat hunting behavior in lions, reproduction in insects, migrations of aquatic organisms, clutch size and parental care in birds, and movement of spiders and raptors. Advanced topics, including the study of dynamic evolutionarily stable strategies, are discussed in Part III.

Mathematical Modeling in Systems Biology

Mathematical Modeling in Systems Biology PDF Author: Brian P. Ingalls
Publisher: MIT Press
ISBN: 0262545829
Category : Science
Languages : en
Pages : 423

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Book Description
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Single-Cell-Based Models in Biology and Medicine

Single-Cell-Based Models in Biology and Medicine PDF Author: Alexander Anderson
Publisher: Springer Science & Business Media
ISBN: 376438123X
Category : Mathematics
Languages : en
Pages : 346

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Book Description
Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.

Modeling Dynamic Phenomena in Molecular and Cellular Biology

Modeling Dynamic Phenomena in Molecular and Cellular Biology PDF Author: Lee A. Segel
Publisher: Cambridge University Press
ISBN: 9780521274777
Category : Mathematics
Languages : en
Pages : 326

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Book Description
The dynamic development of various processes is a central problem of biology and indeed of all the sciences. The mathematics describing that development is, in general, complicated, because the models that are realistic are usually nonlinear. Consequently many biologists may not notice a possible application of theory. They may be unable to decide whether a particular model captures the essence of a system, or to appreciate that analysis of a model can reveal important aspects of biological problems and may even describe in detail how a system works. The aim of this textbook is to remedy the situation by adopting a general approach to model analysis and applying it several times to problems (drawn primarily from molecular and cellular biology) of gradually increasing biological and mathematical complexity. Although material of considerable sophistication is included, little mathematical background is required - only some exposure to elementary calculus; appendixes supply the necessary mathematics and the author concentrates on concepts rather than techniques. He also emphasizes the role of computers in giving a full picture of model behavior and complementing more qualitative analysis. Some problems suitable for computer analysis are also included. This is a class-tested textbook suitable for a one-semester course for advanced undergraduate and beginning graduate students in biology or applied mathematics. It can also be used as a source book for teachers and a reference for specialists.