Author: Nobuhiro Fusetani
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805570988
Category : Medical
Languages : en
Pages : 164
Book Description
The present book consists of three parts: discovery, development and production of drugs from marine organisms. Marine bacteria, fungi, microalgae, sponges and opisthobranch mollusks have attracted much attention as sources of potential drugs, which is described in the first part. A pain-killing drug developed from the venom of a cone shell is a recent highlight of marine natural product research; the interesting story of its discovery is provided. The second part features an anticancer drug with a novel mode of action which was originally isolated from a songe and a potential antiosteoporotic drug of a hexacoral origin. But the most serious problem for development of drugs from the sea remains supply. Two possible solutions, production by fermentation and by aquaculture, are described in the third part. Identification and culture of symbiotic bacteria which are responsible for the production of bioactive sponge metabolites are the main objectives for many researchers.
Drugs from the Sea
Author: Nobuhiro Fusetani
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805570988
Category : Medical
Languages : en
Pages : 164
Book Description
The present book consists of three parts: discovery, development and production of drugs from marine organisms. Marine bacteria, fungi, microalgae, sponges and opisthobranch mollusks have attracted much attention as sources of potential drugs, which is described in the first part. A pain-killing drug developed from the venom of a cone shell is a recent highlight of marine natural product research; the interesting story of its discovery is provided. The second part features an anticancer drug with a novel mode of action which was originally isolated from a songe and a potential antiosteoporotic drug of a hexacoral origin. But the most serious problem for development of drugs from the sea remains supply. Two possible solutions, production by fermentation and by aquaculture, are described in the third part. Identification and culture of symbiotic bacteria which are responsible for the production of bioactive sponge metabolites are the main objectives for many researchers.
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805570988
Category : Medical
Languages : en
Pages : 164
Book Description
The present book consists of three parts: discovery, development and production of drugs from marine organisms. Marine bacteria, fungi, microalgae, sponges and opisthobranch mollusks have attracted much attention as sources of potential drugs, which is described in the first part. A pain-killing drug developed from the venom of a cone shell is a recent highlight of marine natural product research; the interesting story of its discovery is provided. The second part features an anticancer drug with a novel mode of action which was originally isolated from a songe and a potential antiosteoporotic drug of a hexacoral origin. But the most serious problem for development of drugs from the sea remains supply. Two possible solutions, production by fermentation and by aquaculture, are described in the third part. Identification and culture of symbiotic bacteria which are responsible for the production of bioactive sponge metabolites are the main objectives for many researchers.
Sex, Drugs, and Sea Slime
Author: Ellen Prager
Publisher: University of Chicago Press
ISBN: 0226678725
Category : Nature
Languages : en
Pages : 214
Book Description
When viewed from a quiet beach, the ocean can seem calm, even serene. But hidden beneath the sea's waves are a staggering variety of active creatures, engaged in the never-ending struggles of life--to reproduce, to eat, and to avoid being eaten. Marine scientist Ellen Prager takes us deep into the sea to introduce a cast of fascinating and bizarre creatures. From the tiny arrow worms whose voracious ways may lead to death by overeating, to the lobsters that battle rivals or seduce mates with their urine, Prager reveals the ways they interact as predators, prey, or potential mates. And while these animals make for some jaw-dropping stories--there's far more to Prager's account than entertaining anecdotes: again and again, she illustrates the crucial connections between life in the ocean and humankind, in everything from our food supply to our economy, and in drug discovery, biomedical research, and popular culture.--From publisher description.
Publisher: University of Chicago Press
ISBN: 0226678725
Category : Nature
Languages : en
Pages : 214
Book Description
When viewed from a quiet beach, the ocean can seem calm, even serene. But hidden beneath the sea's waves are a staggering variety of active creatures, engaged in the never-ending struggles of life--to reproduce, to eat, and to avoid being eaten. Marine scientist Ellen Prager takes us deep into the sea to introduce a cast of fascinating and bizarre creatures. From the tiny arrow worms whose voracious ways may lead to death by overeating, to the lobsters that battle rivals or seduce mates with their urine, Prager reveals the ways they interact as predators, prey, or potential mates. And while these animals make for some jaw-dropping stories--there's far more to Prager's account than entertaining anecdotes: again and again, she illustrates the crucial connections between life in the ocean and humankind, in everything from our food supply to our economy, and in drug discovery, biomedical research, and popular culture.--From publisher description.
Handbook of Anticancer Drugs from Marine Origin
Author: Se-Kwon Kim
Publisher: Springer
ISBN: 3319071459
Category : Science
Languages : en
Pages : 801
Book Description
This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
Publisher: Springer
ISBN: 3319071459
Category : Science
Languages : en
Pages : 801
Book Description
This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
Pharmaceuticals in Marine and Coastal Environments
Author: Juan Carlos Duran-Alvarez
Publisher: Elsevier
ISBN: 0081029721
Category : Science
Languages : en
Pages : 704
Book Description
Pharmaceuticals in Marine and Coastal Environments: Occurrence, Effects, and Challenges in a Changing World is divided into three sections that address a) coastal areas as the main entrance of pharmaceuticals into the ocean, b) the occurrence and distribution of pharmaceuticals in the environmental compartments of the ocean media, and c) the effects that such pollutants may cause to the exposed marine organisms. With its comprehensive discussions, the book provides a wide depiction of the current state-of-the-art on these topics in an effort to open new sources of investigation and find suitable solutions. - Includes maps edited by the Water Information Network System of the International Hydrological Program (IHP-WINS) - Provides a compilation of information regarding the occurrence and distribution of pharmaceuticals in the marine environment which will help establish new and more efficient monitoring programs and new research lines - Depicts the most important results of environmental risk assessments that can be used as a first step for further toxicological studies
Publisher: Elsevier
ISBN: 0081029721
Category : Science
Languages : en
Pages : 704
Book Description
Pharmaceuticals in Marine and Coastal Environments: Occurrence, Effects, and Challenges in a Changing World is divided into three sections that address a) coastal areas as the main entrance of pharmaceuticals into the ocean, b) the occurrence and distribution of pharmaceuticals in the environmental compartments of the ocean media, and c) the effects that such pollutants may cause to the exposed marine organisms. With its comprehensive discussions, the book provides a wide depiction of the current state-of-the-art on these topics in an effort to open new sources of investigation and find suitable solutions. - Includes maps edited by the Water Information Network System of the International Hydrological Program (IHP-WINS) - Provides a compilation of information regarding the occurrence and distribution of pharmaceuticals in the marine environment which will help establish new and more efficient monitoring programs and new research lines - Depicts the most important results of environmental risk assessments that can be used as a first step for further toxicological studies
Marine Niche: Applications in Pharmaceutical Sciences
Author: Neelam M Nathani
Publisher: Springer Nature
ISBN: 9811550174
Category : Medical
Languages : en
Pages : 454
Book Description
This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases. Biomolecules have potential impacts on a diverse range of fields, including medical and pharmaceutical science, industrial science, biotechnology, basic research, molecular science, environmental science and climate change, etc. To understand and effectively apply medicinally important biomolecules, multidisciplinary approaches are called for. The ocean remains a rich biological resource, and the vast untapped potential of novel molecules from marine bio-resources has caught the interest of more and more researchers. These novel biological compounds have never been found in terrestrial or other ecosystems, but only in this rich niche. Advances in sampling techniques and technologies, along with increased funding for research and nature conservation, have now encouraged scientists to look deeper in the waters. Aquaculture supports both tremendous seafood production and the bulk production of marine-derived drugs. Furthermore, molecular methods are now being extensively employed to explore the untapped marine microbial diversity. With the help of molecular and biotech tools, the ability of marine organisms to produce new biosynthetic drugs can be greatly enhanced. This book provides an extensive compilation of the latest information on marine resources and their undisputedly vital role in the treatment of diverse ailments.
Publisher: Springer Nature
ISBN: 9811550174
Category : Medical
Languages : en
Pages : 454
Book Description
This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases. Biomolecules have potential impacts on a diverse range of fields, including medical and pharmaceutical science, industrial science, biotechnology, basic research, molecular science, environmental science and climate change, etc. To understand and effectively apply medicinally important biomolecules, multidisciplinary approaches are called for. The ocean remains a rich biological resource, and the vast untapped potential of novel molecules from marine bio-resources has caught the interest of more and more researchers. These novel biological compounds have never been found in terrestrial or other ecosystems, but only in this rich niche. Advances in sampling techniques and technologies, along with increased funding for research and nature conservation, have now encouraged scientists to look deeper in the waters. Aquaculture supports both tremendous seafood production and the bulk production of marine-derived drugs. Furthermore, molecular methods are now being extensively employed to explore the untapped marine microbial diversity. With the help of molecular and biotech tools, the ability of marine organisms to produce new biosynthetic drugs can be greatly enhanced. This book provides an extensive compilation of the latest information on marine resources and their undisputedly vital role in the treatment of diverse ailments.
Marine Compounds and Cancer
Author: Friedemann Honecker
Publisher: MDPI
ISBN: 3038427659
Category : Science
Languages : en
Pages : 119
Book Description
This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
Publisher: MDPI
ISBN: 3038427659
Category : Science
Languages : en
Pages : 119
Book Description
This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
Phylum Bryozoa
Author: Thomas Schwaha
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110586312
Category : Nature
Languages : en
Pages : 458
Book Description
With an account of over 6.000 recent and 15.000 fossil species, phylum Bryozoa represents a quite large and important phylum of colonial filter feeders. This volume of the series Handbook of Zoology contains new findings on phylogeny, morphology and evolution that have significantly improved our knowledge and understanding of this phylum. It is a comprehensive book that will be a standard for many specialists but also newcomers to the field of bryozoology.
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110586312
Category : Nature
Languages : en
Pages : 458
Book Description
With an account of over 6.000 recent and 15.000 fossil species, phylum Bryozoa represents a quite large and important phylum of colonial filter feeders. This volume of the series Handbook of Zoology contains new findings on phylogeny, morphology and evolution that have significantly improved our knowledge and understanding of this phylum. It is a comprehensive book that will be a standard for many specialists but also newcomers to the field of bryozoology.
Drugged
Author: Richard J. Miller
Publisher: Oxford University Press, USA
ISBN: 0199957975
Category : History
Languages : en
Pages : 375
Book Description
Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.
Publisher: Oxford University Press, USA
ISBN: 0199957975
Category : History
Languages : en
Pages : 375
Book Description
Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.
Marine Medicine
Author: Eric Weiss
Publisher: The Mountaineers Books
ISBN: 1594856613
Category : Sports & Recreation
Languages : en
Pages : 324
Book Description
CLICK HERE to download the sections on abdominal injury, dislocations, and animal stings from Marine Medicine * Advice for sailing, pleasure boating, fishing, and diving emergencies * More than 100 illustrations * Near-shore or out-at-sea first aid covered * As vital a piece of gear as your PFD and signal flares This edition features the latest information on marine first aid. It includes chapters on hazardous marine life, submersion injury and dive medicine, rescue and evacuation of the sick and injured, wound cleaning and closing, and much more.
Publisher: The Mountaineers Books
ISBN: 1594856613
Category : Sports & Recreation
Languages : en
Pages : 324
Book Description
CLICK HERE to download the sections on abdominal injury, dislocations, and animal stings from Marine Medicine * Advice for sailing, pleasure boating, fishing, and diving emergencies * More than 100 illustrations * Near-shore or out-at-sea first aid covered * As vital a piece of gear as your PFD and signal flares This edition features the latest information on marine first aid. It includes chapters on hazardous marine life, submersion injury and dive medicine, rescue and evacuation of the sick and injured, wound cleaning and closing, and much more.
Red Crew
Author: Jim Howe
Publisher: Naval Institute Press
ISBN: 1682473023
Category : History
Languages : en
Pages : 257
Book Description
Red Crew is a first-hand account of U.S. Coast Guard anti-smuggling operations during the early years of the nation’s maritime war on drugs. Jim Howe describes his experience as the executive officer of a specialized drug-hunting crew that sailed in then-state-of-the-art “surface effect ships,” a small flotilla of high-speed vessels pressed into the drug war on short notice. In the early 1980s, South Florida and the Caribbean were awash in illicit drugs, with hundreds of smuggling organizations bringing huge loads of marijuana, and later cocaine, into the United States. To fight this epidemic, the Reagan administration led a massive effort to disrupt shore-side gangs while bolstering interdiction activity at sea. To increase the number of days at sea for each surface effect ship, a “multi-crewing” concept was employed, with four teams of sixteen sailors—the Red, Blue, Green, and Gold Crews—rotating among three hulls. Through its first-person narrative, Red Crew offers a rare glimpse into the day-to-day pressures, challenges, failures, and successes of Coast Guard cuttermen as they carried out complex and dangerous missions. Red Crew provides a unique historical view of the early days in the Coast Guard’s war on drugs, and is the only book-length history of the diminutive, one-of-a-kind surface effect ship fleet.
Publisher: Naval Institute Press
ISBN: 1682473023
Category : History
Languages : en
Pages : 257
Book Description
Red Crew is a first-hand account of U.S. Coast Guard anti-smuggling operations during the early years of the nation’s maritime war on drugs. Jim Howe describes his experience as the executive officer of a specialized drug-hunting crew that sailed in then-state-of-the-art “surface effect ships,” a small flotilla of high-speed vessels pressed into the drug war on short notice. In the early 1980s, South Florida and the Caribbean were awash in illicit drugs, with hundreds of smuggling organizations bringing huge loads of marijuana, and later cocaine, into the United States. To fight this epidemic, the Reagan administration led a massive effort to disrupt shore-side gangs while bolstering interdiction activity at sea. To increase the number of days at sea for each surface effect ship, a “multi-crewing” concept was employed, with four teams of sixteen sailors—the Red, Blue, Green, and Gold Crews—rotating among three hulls. Through its first-person narrative, Red Crew offers a rare glimpse into the day-to-day pressures, challenges, failures, and successes of Coast Guard cuttermen as they carried out complex and dangerous missions. Red Crew provides a unique historical view of the early days in the Coast Guard’s war on drugs, and is the only book-length history of the diminutive, one-of-a-kind surface effect ship fleet.