Directed Evolution and Synthetic Biology for the Production of Next Generation Biofuels

Directed Evolution and Synthetic Biology for the Production of Next Generation Biofuels PDF Author: Lucy Green
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Directed Evolution and Synthetic Biology for the Production of Next Generation Biofuels

Directed Evolution and Synthetic Biology for the Production of Next Generation Biofuels PDF Author: Lucy Green
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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New Biotechnologies for Increased Energy Security

New Biotechnologies for Increased Energy Security PDF Author: Juan Carlos Serrano-Ruiz
Publisher: CRC Press
ISBN: 1771882360
Category : Science
Languages : en
Pages : 335

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Book Description
This title includes a number of Open Access chapters. The information contained in this compendium volume sets the stage for the future's large-scale production of biofuels. Biomass is an abundant carbon-neutral renewable feedstock for producing fuel. First-generation biofuels gained attention for their problems, but the authors of this book demons

Synthetic Biology

Synthetic Biology PDF Author: Huimin Zhao
Publisher: Academic Press
ISBN: 0123978203
Category : Science
Languages : en
Pages : 352

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Book Description
Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development

Industrialization of Biology

Industrialization of Biology PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309316553
Category : Science
Languages : en
Pages : 158

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Book Description
The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.

Synthetic Biology

Synthetic Biology PDF Author: Markus Schmidt
Publisher: John Wiley & Sons
ISBN: 3527659277
Category : Science
Languages : en
Pages : 267

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Book Description
This is the only book to focus on industrial and environmental applications of synthetic biology, covering 17 of the most promising uses in the areas of biofuel, bioremediation and biomaterials. The contributions are written by experts from academia, non-profit organizations and industry, outlining not only the scientific basics but also the economic, environmental and ethical impact of the new technologies. This makes it not only suitable as supplementary material for students but also the perfect companion for policy makers and funding agencies, if they are to make informed decisions about synthetic biology. Largely coordinated by Markus Schmidt, a policy adviser, and the only European to testify in front of the bioethics commission of the Obama administration.

New Frontiers and Applications of Synthetic Biology

New Frontiers and Applications of Synthetic Biology PDF Author: Vijai Singh
Publisher: Elsevier
ISBN: 0128244690
Category : Science
Languages : en
Pages : 486

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Book Description
New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. Offers basic understanding and knowledge in several aspects of synthetic biology Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more

Developing Biofuel Bioprocesses Using Systems and Synthetic Biology

Developing Biofuel Bioprocesses Using Systems and Synthetic Biology PDF Author: Sylvia M. Clay
Publisher: Springer Science & Business Media
ISBN: 1461455804
Category : Science
Languages : en
Pages : 70

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Book Description
Advances in technological and analytical methods have fostered rapid growth of systems biology and synthetic biology. There continues to be rapid changes and discoveries in both fields with a small number of recent peer-reviewed reviews indicating some of the relationships between systems biology and synthetic biology. This proposed SpringerBrief will cover core concepts of systems biology and synthetic biology and illustrate the implementation of associated research methodologies for an integrated approach to specifically address engineering microorganisms for biofuel production.​

BIOFUELS

BIOFUELS PDF Author: B. Bharathiraja
Publisher: MJP Publisher
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 380

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Book Description
Today the world is facing three critical problems: (i) High fuel prices, (ii) Climatic changes (iii) Air pollution. Currently there are several important problems to be resolved worldwide: (1) high need for energy, (2) high depletion of non-renewable energy resources and (3) high local and global environmental pollution. This book “Biofuels - A Promising alternate for next generation fuels” deals with the production of biofuels. The biggest difference between biofuels and petroleum feedstock is oxygen content. Biofuels have oxygen levels from 10% to 45% while petroleum has essentially none making the chemical properties of biofuels very different from petroleum. Oxygenates are just pre-used hydrocarbons having a structure that provides a reasonable antiknock value. Most traditional biofuels, such as ethanol from corn, wheat, or sugar beets, and biodiesel from oil seeds, are produced from classic agricultural food crops that require high-quality agricultural land for growth. The term biofuel is referred to as liquid or gaseous fuels for the transport sector that are predominantly produced from biomass. There are several reasons for biofuels to be considered as relevant technologies by both developing and industrialized countries. They include energy security reasons, environmental concerns, foreign exchange savings, and socioeconomic issues related to the rural sector. Biomass can be converted to biofuels through various methods like chemical, such as biomethanol and biodiesel production, thermochemical, such as bio-oil, bio-syngas, biohydrogen production, and biochemical, such as bioethanol, biogas, biodiesel and biohydrogen production.

The Science and Applications of Synthetic and Systems Biology

The Science and Applications of Synthetic and Systems Biology PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309219396
Category : Science
Languages : en
Pages : 570

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Book Description
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Biotechnology for Biofuel Production and Optimization

Biotechnology for Biofuel Production and Optimization PDF Author: Carrie A Eckert
Publisher: Elsevier
ISBN: 0081000537
Category : Science
Languages : en
Pages : 574

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Book Description
Biotechnology for Biofuel Production and Optimization is the compilation of current research findings that cover the entire process of biofuels production from manipulation of genes and pathways to organisms and renewable feedstocks for efficient biofuel production as well as different cultivation techniques and process scale-up considerations. This book captures recent breakthroughs in the interdisciplinary areas of systems and synthetic biology, metabolic engineering, and bioprocess engineering for renewable, cleaner sources of energy. Describes state-of-the-art engineering of metabolic pathways for the production of a variety of fuel molecules Discusses recent advances in synthetic biology and metabolic engineering for rational design, construction, evaluation of novel pathways and cell chassis Covers genome engineering technologies to address complex biofuel-tolerant phenotypes for enhanced biofuel production in engineered chassis Presents the use of novel microorganisms and expanded substrate utilization strategies for production of targeted fuel molecules Explores biohybrid methods for harvesting bioenergy Discusses bioreactor design and optimization of scale-up