Dibenzanthracenes and Environmental Carcinogenesis PDF Download
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Author: Walter Karcher
Publisher: Cambridge University Press
ISBN: 9780521303828
Category : Medical
Languages : en
Pages : 296
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Book Description
A systematic survey of the dibenzanthracenes and of their chemical, physiochemical, and biological properties, this book treats the nomenclature, the chemical and physical properties, and the synthesis and preparation of the five principal isomers of the dibenzanthracene series: dibenz (a, h), dibenz (a, c), dibenz (a, j), anthracene, benzo(a)naphthacene, and pentacene. Other chapters are devoted to their occurrence and analysis in the environment, in industrial processes and effluents, and in foodstuffs. T second part addresses their biological activity and reviews the metabolism, cellular interactions, toxicology, mutagenicity, and carcinogenicity of the dibenzanthracenes. The final chapter is devoted to structure-activity relationships in this class of the aromatic compounds.
Author: Walter Karcher
Publisher: Cambridge University Press
ISBN: 9780521303828
Category : Medical
Languages : en
Pages : 296
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Book Description
A systematic survey of the dibenzanthracenes and of their chemical, physiochemical, and biological properties, this book treats the nomenclature, the chemical and physical properties, and the synthesis and preparation of the five principal isomers of the dibenzanthracene series: dibenz (a, h), dibenz (a, c), dibenz (a, j), anthracene, benzo(a)naphthacene, and pentacene. Other chapters are devoted to their occurrence and analysis in the environment, in industrial processes and effluents, and in foodstuffs. T second part addresses their biological activity and reviews the metabolism, cellular interactions, toxicology, mutagenicity, and carcinogenicity of the dibenzanthracenes. The final chapter is devoted to structure-activity relationships in this class of the aromatic compounds.
Author: Piet Emmelot
Publisher: North Holland
ISBN:
Category : Medical
Languages : en
Pages : 424
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Book Description
Author:
Publisher:
ISBN:
Category : Polycyclic aromatic hydrocarbons
Languages : en
Pages : 500
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Book Description
Author: G. Grimmer
Publisher: CRC Press
ISBN: 1351080202
Category : Science
Languages : en
Pages : 272
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Book Description
The present survey comprises today‘s knowledge of environmental pollution in particular of the atmosphere by PAH and of the biological effects of this class of substance, putting special emphasis on their carcinogenic activity. The research data and conclusions derived therefrom are meant to assist the government of the Federal Republic of Germany in determining an air quality standard.
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0123948312
Category : Medical
Languages : en
Pages : 479
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Book Description
This volume explores some of the most exciting recent advances in basic research on animal models of molecular pathology. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields
Author: Trevor M. Penning
Publisher: Springer Science & Business Media
ISBN: 1617379956
Category : Medical
Languages : en
Pages : 447
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Book Description
This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.
Author:
Publisher:
ISBN:
Category : Carcinogenesis
Languages : en
Pages : 1004
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Book Description
Author: United States. Surgeon General's Advisory Committee on Smoking and Health
Publisher:
ISBN:
Category : Smoking
Languages : en
Pages : 406
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Book Description
Author: Rhoda G.M. Wang
Publisher: CRC Press
ISBN: 1351361740
Category : Medical
Languages : en
Pages : 544
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Book Description
Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants. Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development. The book will also benefit individuals in environmental, regulatory, and registration affairs, as well as academicians and students.
Author: United States. Environmental Protection Agency. Office of Toxic Substances
Publisher:
ISBN:
Category : Carcinogens
Languages : en
Pages : 612
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Book Description
