Developmental Biology: Manipulation of mammalian development

Developmental Biology: Manipulation of mammalian development PDF Author: Leon W. Browder
Publisher:
ISBN:
Category : Developmental biology
Languages : en
Pages :

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Developmental Biology: Manipulation of mammalian development

Developmental Biology: Manipulation of mammalian development PDF Author: Leon W. Browder
Publisher:
ISBN:
Category : Developmental biology
Languages : en
Pages :

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Manipulation of Mammalian Development

Manipulation of Mammalian Development PDF Author: Ralph B.L. Gwatkin
Publisher: Springer Science & Business Media
ISBN: 1461321433
Category : Science
Languages : en
Pages : 397

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Book Description
Developmental biology has been transformed recently by discoveries in the fields of molecular biology, cell biology, and immunology. New ways of manip ulating mammalian development are uncovering control mechanisms and ena bling us to apply them in solving practical problems in animal production and human health. This book outlines some of these new manipulations and how they have contributed to the present state of developmental biology. Chapter 1 describes gene transfer by micro injection of cloned recombinant DNA into zygotes. Although the factors that affect transformation frequencies and integration sites are still unknown, such techniques offer a number of exciting prospects. Research models for human disease coula be artificially created and desirable characteristics in agricultural animals could be - hanced. . The theme of cell-to-cell transfer is continued in Chapters 2 and 3. Chapter 2 describes pronuclear transplantation by Sendai virus-induced fusion of the karyoplast with the enucleated embryo. Using this procedure, it has been dem onstrated that both male and female genomes are essential for normal develop ment, although the reason for this is not yet understood. Chapter 3 describes studies on the fusion of whole oocytes. .

The Molecular Biology of Cell Determination and Cell Differentiation

The Molecular Biology of Cell Determination and Cell Differentiation PDF Author: Leon W. Browder
Publisher: Springer
ISBN: 9780306427350
Category : Science
Languages : en
Pages : 460

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Book Description
This series was established to create comprehensive treatises on specific topics in developmental biology. Such volumes serve a useful role in developmental biology, which is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting ground for the various practi tioners of this science, facilitating an integration of heterogeneous information on specific topics. Each volume is comprised of chapters selected to provide the conceptual basis for a comprehensive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of developmental biology should understand the experimental back ground of the specialty and be able to place that body of information in context, in order to ascertain where additional research would be fruitful. The creative process then generates new experiments. This series is intended to be a vital link in that ongoing process of learning and discovery.

Mammalian Development

Mammalian Development PDF Author: Peter Lonai
Publisher: CRC Press
ISBN: 9783718659203
Category : Nature
Languages : en
Pages : 406

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Book Description
"This book aims to provide a survey of the developmental biology of mammals--Pref.

Mammalian Development

Mammalian Development PDF Author: Patrick P. L. Tam
Publisher:
ISBN: 9781936113248
Category : Science
Languages : en
Pages : 0

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Book Description
"A subject collection from Cold Spring Harbor perspectives in biology."

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309070864
Category : Nature
Languages : en
Pages : 348

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Book Description
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Development and Reproduction in Humans and Animal Model Species

Development and Reproduction in Humans and Animal Model Species PDF Author: Werner A. Mueller
Publisher: Springer
ISBN: 3662437848
Category : Science
Languages : en
Pages : 723

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Book Description
This book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development; genes controlling development and their contemporary molecular-analysis methods; production of clones and transgenic animals; development of the nervous and circulatory systems; regenerative medicine and ageing. Finally the evolution of developmental toolkits and novelties is discussed including the genetic basis of the enlargement of the human forebrain. Separate boxes are devoted to controversial questions such as the benefits and problems of prenatal diagnostics or the construction of ancient body plans.

Molecular Biology of The Cell

Molecular Biology of The Cell PDF Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Animal Applications of Research in Mammalian Development

Animal Applications of Research in Mammalian Development PDF Author: Roger A. Pedersen
Publisher: Banbury Report
ISBN:
Category : Medical
Languages : en
Pages : 360

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Book Description
Recent progress in cell and molecular biology has profound implications for understanding the developmental biology of mammalian embryos. The unifying theme of this volume is a cellular and molecular approach to gametogenesis, embryogenesis, and maternal-fetal interactions in the developmental biology of agriculturally significant mammals. Great progress has been achieved in our understanding of preimplantation mammalian embryogenesis in laboratory species, particularly the mouse, through application of cell and embryo culture methods, cell biological techniques, and, more recently, recombinant DNA technology. A major remaining opportunity is the application of these techniques to problems in domestic species, such as improved methods for in vitro growth and maturation of oocytes, egg and embryo cryopreservation, and genetic manipulation to enhance productivity and herd quality. The authors review current knowledge in key areas, emphasizing new approaches to unsolved problems in the developmental biology of domestic species.

Early Mammalian Development

Early Mammalian Development PDF Author: Matthew H. Kaufman
Publisher: Cambridge University Press
ISBN: 9780521254496
Category : Science
Languages : en
Pages : 288

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Book Description