Deutsche Gesellschaft Für Experimentelle und Klinische Pharmakologie und Toxikologie - Abstracts of the 51st Annual Meeting, 2010 PDF Download
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Author: Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Deutsche Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie
Publisher:
ISBN:
Category :
Languages : en
Pages : 92
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Book Description
Author: Harris G. Fienberg
Publisher: Springer
ISBN: 364254827X
Category : Medical
Languages : en
Pages : 224
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Book Description
This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers.
Author: G. Balakrish Nair
Publisher: Springer
ISBN: 3642554040
Category : Medical
Languages : en
Pages : 267
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Book Description
The most feared attribute of the human pathogen Vibrio cholerae is its ability to cause outbreaks that spread like wildfire, completely overwhelming public health systems and causing widespread suffering and death. This volume starts with a description of the contrasting patterns of outbreaks caused by the classical and El Tor biotypes of V. cholerae. Subsequent chapters examine cholera outbreaks in detail, including possible sources of infection and molecular epidemiology on three different continents, the emergence of new clones through the bactericidal selection process of lytic cholera phages, the circulation and transmission of clones of the pathogen during outbreaks and novel approaches to modeling cholera outbreaks. A further contribution deals with the application of the genomic sciences to trace the spread of cholera epidemics and how this information can be used to control cholera outbreaks. The book closes with an analysis of the potential use of killed oral cholera vaccines to stop the spread of cholera outbreaks.
Author: Glenn Dranoff
Publisher: Springer Science & Business Media
ISBN: 3642141366
Category : Medical
Languages : en
Pages : 313
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Book Description
The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Author: Jürgen A. Richt
Publisher: Springer Science & Business Media
ISBN: 3642368719
Category : Medical
Languages : en
Pages : 306
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Book Description
From the first detailed clinical description of the disease in the Midwestern United States in 1918, to the isolation of the causative agent, the first of any influenza virus, in 1930 to its role in the genesis of the 2009 human pandemic, swine have played a central role in the ecology of influenza. Although not considered the major natural reservoir for influenza A viruses, swine are host to a limited but dynamic assortment of viruses. A number of subtypes of influenza A viruses of human and avian origin, including H1, H2, H3, H4, H5, H7, and H9, have been isolated from global swine populations. Most of these isolations have, however, been limited in number and it is only H1 and H3 influenza viruses that are known to have formed stable lineages in swine. In this respect, swine influenza viruses (SIV) are similar to their counterparts in humans where H1 and H3 viruses have also been maintained. The nature of these H1 and H3 viruses differ between the two host populations, however, and, as discussed throughout this book, are even different in swine populations in different geographic regions of the world due to multiple introductions of avian and human influenza viruses.
Author: C. K. Atterwill
Publisher: Cambridge University Press
ISBN: 9780521326841
Category : Medical
Languages : en
Pages : 490
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Book Description
The volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists.
Author: Norman James Harper
Publisher:
ISBN: 9780120133079
Category :
Languages : en
Pages : 232
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Book Description
Author: Walter Burgdorf
Publisher: Springer Science & Business Media
ISBN: 1461252644
Category : Medical
Languages : en
Pages : 222
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Book Description
1982, published (in German) Histopathologie It is a great honor to be allowed to present my der Hautkrankheiten. Dr. Nasemann has gra concepts of basic dermatopathology. I have ciously allowed me to write my own English long joked that I wished to write a book enti text, completely reorganizing and changing his tled Dermatopathology for Dick and Jane already superb text, but using about one half (with apologies to the author of my first-grade reader), but finally concluded that a more dig of his photomicrographs and all of his line drawings. I have taken the balance of the pho nified title-Dermatopathology-was more appropriate. This book is aimed at a very spe tomicrographs myself, while Dr. Curt Littler cific readership-first-year residents in pathol has provided a number of new illustrations. Dr. ogy and dermatology, as they begin to learn Littler, who is somewhat closer to his first year skin pathology. My hope is that the book will of residency than I, helped to write the intro be used, worn out, and retired to the bookshelf ductory chapters with the goal of providing as the young physician's sophistication in just that information which his contemporaries would find most useful. creases. Thus, a copy that is pristine and not dog-eared has not fulfilled its purpose. I must add that I take full responsibility for This little manual cannot compete with the 'his text.
Author: Andrew P. Keaveny
Publisher: Springer
ISBN: 3319136143
Category : Medical
Languages : en
Pages : 348
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Book Description
This volume presents a concise yet comprehensive overview on all facets concerning the complications of cirrhosis. Structured in three sections, the book reviews the natural history of cirrhosis, the diagnostic and predictive tools available to assess the disease, complications, and treatment options such as liver assist devices and transplantation. Topical concerns in the management of patients with cirrhosis are also addressed, including issues pertaining to the delivery of quality care in this patient population. Written by experts in their fields, Complications of Cirrhosis: Evaluation and Management serves as a valuable resource for practitioners and physicians-in-training on the subject of cirrhosis.
