Author: John F. Bates
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 164

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Book Description

Author: Sandra Knowles Weller
Publisher: Caister Academic Press Limited
ISBN: 9781904455769
Category : Science
Languages : en
Pages : 0

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Book Description
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.

Author:
Publisher:
ISBN:
Category : Idaho
Languages : en
Pages :

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Book Description

Author: Dave Gorman
Publisher: Random House
ISBN: 144814633X
Category : Humor
Languages : en
Pages : 364

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Book Description
If someone called you a 'googlewhack' what would you do? Would you end up playing table tennis with a nine year-old boy in Boston? Would you find yourself in Los Angeles wrangling snakes, or would you go to China to be licked by a performance artist? If your name is Dave Gorman, then all of these things could be true. Fuelled by a lust for life and a desperate desire to do anything except what he's supposed to be doing (writing that novel and growing up), Dave falls under the spell of an obscure internet word game - Googlewhacking. Addicted to the game, and gripped by obsession, Dave travels three times round the world, visiting four continents and the unlikeliest cast of real life eccentrics you'll ever meet in what becomes an epic challenge, a life-changing, globe-trotting Googlewhack adventure.

Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 774

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Book Description

Author: George Sylvan Bobinski
Publisher: Littleton, Colo. : Libraries Unlimited
ISBN:
Category : Biography & Autobiography
Languages : en
Pages : 648

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Book Description
A biographical directory of United States political leaders.