Current Concepts in Gastric Cytoprotection

Current Concepts in Gastric Cytoprotection PDF Author: Steven P. Mistilis
Publisher:
ISBN:
Category :
Languages : en
Pages : 28

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Book Description

Current Concepts in Gastric Cytoprotection

Current Concepts in Gastric Cytoprotection PDF Author: Steven P. Mistilis
Publisher:
ISBN:
Category :
Languages : en
Pages : 28

Get Book Here

Book Description


Current Concepts in Gastric Cytoprotection

Current Concepts in Gastric Cytoprotection PDF Author: Steven P. Mistilis
Publisher:
ISBN:
Category :
Languages : en
Pages : 28

Get Book Here

Book Description


Gastric Cytoprotection

Gastric Cytoprotection PDF Author: Daniel Hollander
Publisher: Springer Science & Business Media
ISBN: 1468456970
Category : Medical
Languages : en
Pages : 228

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Book Description
Gastric secretions contain hydrogen ions at a concentration that is more than one million times higher than their intracellular concentration. This phenomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse quently, over the past 150 years, we have made considerable progress in under standing the mechanisms and regulation of acid secretion by the stomach. Not surprisingly, therapy for both peptic disease and mucosal injury has also been predominantly directed at either neutralizing acid or suppressing its production. During the past 10 years, attention has been focused on factors other than acid in the genesis and therapy of ulcer disease. Work done worldwide demon strated that acid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas troduodenal mucosa is normally protected by a complex series of events includ ing mucus and bicarbonate secretion, cell renewal, surface mucosal restitution, and preservation of the microvasculature and mucosal proliferative zone.

Modern Concepts in Gastroenterology

Modern Concepts in Gastroenterology PDF Author: Alan B.R. Thomson
Publisher: Springer Science & Business Media
ISBN: 1461317894
Category : Medical
Languages : en
Pages : 376

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Book Description
A fine team of state-of-the-art researcher/clinicians who know their fields, have contributed to the advancement of knowledge, and are in a position to judge what is truly important have here pooled their thoughts in a series of chapters on the cutting edges of gastroenterology. Four attributes render this volume superior to other update-oriented publications. The first striking feature, which is immediately evident upon scanning the table of contents, is the imaginative choice of subjects, ranging from trav eler's diarrhea and sexually transmitted GI infections through TPN and interventional endoscopy to geriatrics and iatrogenic disease. A second outstanding feature of this volume is its success in balanc ing basic pathophysiology with practical considerations of clinical man agement. This is achieved in the discussions of such diverse topics as acid-peptic diseases, infectious and other diarrheal syndromes, and hep atitis immunization. Throughout the book we are led smoothly from basic science principles to specific recommendations for diagnosis and therapy. This practical emphasis appears repeatedly and sometimes pro duces a delightful surprise, such as a chapter on radiology that is not tech nology-based but instead problem-oriented.

The Medical Journal of Australia

The Medical Journal of Australia PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 556

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Book Description


Current Catalog

Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1712

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Book Description
First multi-year cumulation covers six years: 1965-70.

Prognosis in the Rheumatic Diseases

Prognosis in the Rheumatic Diseases PDF Author: N. Bellamy
Publisher: Springer Science & Business Media
ISBN: 9401138966
Category : Medical
Languages : en
Pages : 771

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Book Description
Seer, forecaster, prophet, geomancer, or tout - all predict future events as physicians must. The medical activity is prognosis from the Greek pro (forward) and gnosis (special knowledgeL thus foreknowledge, and the practitioner is the prognosticator, a sobriquet which falls unhappily upon the ear. Like it or not, there is nothing more critical in the management of chronic rheumatic conditions than a reasonably clear picture of what time and disease will bring. The knowledge is so much a part of ordinary medical thinking that we rarely grace it with the label prognosis. But, like so much of "ordinary medical thinking" (an oxymoron, perhaps), quantitative data are very thin and the chestnuts of personal observation and authority figure assertion loom large. Unlike several books I have seen or written, this one on prognosis needs no justification. The entirety of a person's life contributes to and confounds what the future holds. The ingredients include education levet income, support structures such as family, housing, occupation, availability of medical services, diagnosis, treatment, rate of disease progression, age, gender, race, marital status, and others too numerous to mention or too arcane to be recognized. One would think the task of estimating prognosis impossible. And yet there is light on the horizon -we do know a few things such as the effect of high rheumatoid factor titers on the prognosis of RA or the likely outcome of certain kidney lesions in SLE.

Cell/Tissue Injury and Cytoprotection/Organoprotection in the Gastrointestinal Tract

Cell/Tissue Injury and Cytoprotection/Organoprotection in the Gastrointestinal Tract PDF Author: Ludmila P. Filaretova
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318021830
Category : Medical
Languages : en
Pages : 259

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Book Description
Up-to-date reviews on the mechanisms of gastrointestinal injury and protection In recent years, there have been significant advances both in understanding the mechanisms involved in gastrointestinal mucosal injury and protection, as well as in the development of successful strategies for prevention and treatment of gastrointestinal injury. Nevertheless, many people worldwide still suffer from gastrointestinal damage. This book contains contributions by an international panel of researchers in the form of up-to-date reviews on the mechanisms of gastrointestinal injury and protection. These are complemented by papers discussing how these new findings about cell/tissue injury and cytoprotection/organoprotection can be applied to the prevention and treatment of tissue damage in the gastrointestinal tract. Moreover, the publication includes a special chapter on Andre Robert, who has discovered the phenomenon of gastric cytoprotection. This publication will be of great interest for both basic and clinical researchers in gastroenterology and pharmacology, reviewing the advances made so far and pointing towards future developments.

Capsaicin - Sensitive Neural Afferentation and the Gastrointestinal Tract

Capsaicin - Sensitive Neural Afferentation and the Gastrointestinal Tract PDF Author: Gyula Mozsik
Publisher: BoD – Books on Demand
ISBN: 9535116312
Category : Medical
Languages : en
Pages : 382

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Book Description
The capsaicin, a component of paprika, has been used in the culinary practice of every day nutritional practice. This agent is known to cause a variety of actions in the body through activating capsaicin-sensitive afferent neurons. A recently launched book entitled, Capsaicin-Sensitive Neural Afferentation and the Gastrointestinal Tract: from Bench to Bedside, is attractive for several reasons. First, Prof. Mozsik, a chief editor of this book, is known internationally as an expert in capsaicin pharmacology. Since he has worked for many years as a head of internal medicine, taking care of patients with various GI diseases, he is able to make a correct interpretation of various findings obtained in basic researches to clinical events. Second, although there are many articles about capsaicin, they mostly deal with basic research and finding but do not include much about clinical finding. Third, this book encompassed review articles written by internationally accepted scientists leading the field of capsaicin research, who highlighted the current state of knowledge on pharmacology, physiology and clinical phathophysiology of capsaicin-sensitive afferent neurons, and discussed directions for future research. Overall, this book is for people who are interested in the capsaicin action in body.

Ulcer Disease

Ulcer Disease PDF Author: Sandor Szabo
Publisher: CRC Press
ISBN: 9780849362163
Category : Medical
Languages : en
Pages : 494

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Book Description
The latest data on the pathogenesis of ulcer disease is presented in this text, with the emphasis that an understanding of the pathogenesis and etiology of ulcer diseases represents the most rational approach to pharmacology - the prevention and treatment of ulcer disease. Early and late biochemical and functional changes, morphologic stages of the injury and healing phases, as well as vascular factors in ulceration are highlighted. In addition, new pathogenetic elements on neuroendocrine and other endogenous modulators and circadian rhythms in ulcerogenesis are covered. The section on new pharmacology consists of several chapters presenting new animal models of gastric, small intestinal and colonic ulcers because in vivo models represent the basis to test and accurately detect new antiulcer drugs. A large series of chapters cover new drugs for ulcer prevention and treatment. This book is indispensible to investigators in basic and applied research, academic and industrial pharmacologists and clinicians in gastroenterology.