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Author: Paul C. Guest
Publisher: Springer
ISBN: 9783319524788
Category : Science
Languages : en
Pages : 0
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Book Description
Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.
Author: Paul C. Guest
Publisher: Springer
ISBN: 9783319524788
Category : Science
Languages : en
Pages : 0
Get Book Here
Book Description
Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.
Author: Scott Walter Stevenson
Publisher:
ISBN: 9780990471813
Category :
Languages : en
Pages : 440
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Book Description
This book is a strategic plan and resource manual covering bodybuilding from A-Z: In-depth perspective on goal setting, dietary manipulations, nutritional supplementation, posing/presentation, and dozens of other topics including peak week, "metabolic damage," training after 40 and being a critical-thinking bodybuilder. >2000 scientific references.
Author:
Publisher:
ISBN:
Category : Containers
Languages : en
Pages : 8
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Book Description
Author:
Publisher:
ISBN:
Category : Bicycle trails
Languages : en
Pages : 110
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Book Description
The fiscal year 1991 U.S. DOT Appropriations Act directed the Secretary of Transportation to conduct a National Bicycling and Walking Study. The five objectives of the study as specified in the Act were to: (1) Determine the current levels of bicycling and walking and identify reasons they are not better used as means of transportation; (2) Develop a plan for the increased use and enhanced safety of these modes and identify the resources necessary to implement and achieve this plan; (3) Determine the full costs and benefits of promoting bicycling and walking in urban and suburban areas; (4) Review and evaluate the success of promotion programs around the world to determine their applicability to the role required of the U.S. DOT to implement a successful program; and (5) Develop an action plan, including timetable and budget, for implementation of such Federal transportation policy. The purpose of this Interim Report is to document progress in addressing these five objectives. In dealing with each objective, this report summarizes available information, discusses what additional information is required, and outlines the approach to be used in collecting it.
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ISBN:
Category : Population forecasting
Languages : en
Pages : 334
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Book Description
Author: Cengage Learning
Publisher: Cengage Learning
ISBN: 9781580017329
Category : Building laws
Languages : en
Pages : 0
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Book Description
"Now includes International Private Sewage Disposal Code"--Cover.
Author: Jonathan Leeman
Publisher:
ISBN: 9781537163529
Category :
Languages : en
Pages : 52
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Book Description
9Marks Journal: RevitalizeChurch planting is a great thing, and there's no need to take anything away from it. But there should also be a default setting in a Christian's heart that always longs to see dying churches revitalized. It's not like the debate in your head about whether to fork over $2000 to the mechanic to fix your clunker of a car or to just buy a new one. It's more like a decision about whether to walk away from a dear but difficult relationship. Our hearts should never want to do that, even if once in a great while we must.Start with Andy Davis' remarkable story of reforming one church, and you'll find something that feels strangely like it's from the Bible, as if Andy were only doing what the apostles did. Then let the biblical burden of Bobby Jamieson's article sit on you. I'm serious. You just might find some new light bulbs turning on. Matt Schmucker's and Mike McKinley's articles then round out the apologetic by offering crisp statements for why churches and pastors should pursue the work of revitalizing.If you are a pastor, keep reading into the next section, where Jeramie Rinne, Greg Gilbert, John Folmar, J. D. Greear, and Brian Croft offer valuable and practical wisdom on how to proceed with the work of reform.Could it be that church revitalization does not loom as large in the modern evangelical mindset as it did in Jesus' and the apostles'? Before you answer that question, if nothing else, read Bobby's article. You just might wonder if we've missed something basic.
Author: Clara Stearns Scarbrough
Publisher: Eakin Press
ISBN: 9781571689153
Category : Williamson County (Tex.)
Languages : en
Pages : 530
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Book Description
Author: Michael Ventura
Publisher: Spring Publications
ISBN:
Category : History
Languages : en
Pages : 264
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Book Description
"I'd rather have one or two of his whiplashing essays in my hands than almost any tome of philosophy". -- Thomas Moore
Author: Turk Pipkin
Publisher:
ISBN: 9781881484073
Category : Colorado River (Tex.)
Languages : en
Pages : 103
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Book Description
The history of the Lower Colorado River Authoity and its generating electricity for Central Texas.
