Crystalline Bacterial Cell Surface Layers PDF Download
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Author: Uwe B. Sleytr
Publisher: Springer Science & Business Media
ISBN: 3642735371
Category : Science
Languages : en
Pages : 205
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Book Description
Crystalline surface layers (S-layers) represent an almost universal feature of archaebacterial cell envelopes and can be found in gram-positive and gram-negative eubacterial species from nearly all phylogenetic branches. S-layers consist of a single protein- or glycoprotein species and thus can be considered as one of the most primitive membrane structures developed during evolution. Prokaryotes carrying S-layers are ubiquitously found in every part of the biosphere. This supports the concept of a general supramolecular "porous crystalline surface layer" fulfilling a broad spectrum of functions which are strongly dependent on the particular environmental and ecological conditions. Their structural simplicity makes S-layers a suitable model for analyzing structure-function relationships as well as dynamic aspects of membrane morphogenesis.
Author: Uwe B. Sleytr
Publisher: Springer Science & Business Media
ISBN: 3642735371
Category : Science
Languages : en
Pages : 205
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Book Description
Crystalline surface layers (S-layers) represent an almost universal feature of archaebacterial cell envelopes and can be found in gram-positive and gram-negative eubacterial species from nearly all phylogenetic branches. S-layers consist of a single protein- or glycoprotein species and thus can be considered as one of the most primitive membrane structures developed during evolution. Prokaryotes carrying S-layers are ubiquitously found in every part of the biosphere. This supports the concept of a general supramolecular "porous crystalline surface layer" fulfilling a broad spectrum of functions which are strongly dependent on the particular environmental and ecological conditions. Their structural simplicity makes S-layers a suitable model for analyzing structure-function relationships as well as dynamic aspects of membrane morphogenesis.
Author:
Publisher:
ISBN:
Category : Bacterial cell surfaces
Languages : en
Pages : 230
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Book Description
Author: Uwe B. Sleytr
Publisher: Elsevier
ISBN: 0080548415
Category : Science
Languages : en
Pages : 245
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Book Description
Crystalline Bacterial Cell Surface Proteins assembles information on the understanding of the occurrence, structure, chemistry, genetics, assembly, function, and application potential of S-layers. The chapters are designed to stand independent of each other and provide a complete survey of the different topics in S-layer research. This book is intended to stimulate further development in basic and applied S-layer research. Assembles present-day understanding of S-layers Provides a detailed survey of the entire field of basic and applied S-layer research Potential for broad application in biotechnology, vaccine development, diagnostics, molecular nanotechnology, and biomimetics
Author: Terry J. Beveridge
Publisher: Springer Science & Business Media
ISBN: 1475790325
Category : Science
Languages : en
Pages : 328
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Book Description
This book is a compilation of the research which was presented during the NATO-Advanced Research Workshop (ARW) entitled "Advances in Bacterial Paracrystalline Surface Layers" held in London, Ontario, Canada during September 27 to 30, 1992. The organizing committee consisted of the two Workshop directors, S. F. Kaval and T. J. Beveridge, and H. König, U. B. Sleytr and T. J. Trust; their summary statements about the significance and success of the NATO-ARWare in Chapter 37 of this book. This was the third international workshop on bacterial S-layers and it demonstrated unequivocally how rapidly research is progressing. The Workshop was made possible by financial support from the North Atlantic Treaty Organization (NATO), the Medical Research Council of Canada (MRC), the Natural Seiences and Engineering Research Council of Canada (NSERC), and the Canadian Bacterial Diseases Network (CBDN) which is a Canadian National Centre of Excellence (NCE). We are very grateful for the support from all of these agencies since their financial aid made it possible to bring to London, Canada a truly international group of S-layer experts. We encouraged the attendance and participation of graduate fellows and research associates, and their presentations students, postdoctoral was an intense three constitute the "Poster" section of this book. The NATO-ARW day workshop held at a delightful secluded location (Spencer Hall) so that the delegates had both formal and informal occasions to interact and evolve new ideas.
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: Ajit Varki
Publisher: CSHL Press
ISBN: 9780879696818
Category : Medical
Languages : en
Pages : 694
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Book Description
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author: K.J. Towner
Publisher: Springer Science & Business Media
ISBN: 1489935533
Category : Science
Languages : en
Pages : 450
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Book Description
The 1st International Workshop on Acinetobacter was held on 6th September, 1986, in Manchester, England, in association with the 14th International Congress of Microbiology. That occasion was so well attended and productive that there were soon discussions about how, when and where the next meeting should be held. This time, however, there was sufficient confidence to think of a more substantial meeting and to plan for the proceedings to be published. It emerged that there was wide agreement that the time was ripe to take stock of the entire biology of Acinetobacter: its occurrence and taxonomy; its molecular biology, biochemistry and physiology; its clinical importance and its industrial and commercial applications. The 2nd International Workshop on Acinetobacter took place from 6th to 7th September, 1990, at the Institut Pasteur, Paris, and was sponsored by the Federation of European Microbiological Societies. There were about 100 participants from 19 countries. The backbone of the meeting consisted of 23 plenary lectures. There were 28 posters and the meeting closed with a general discussion which went on long after the official finishing time despite all the counter-attractions of a sunny Parisian Friday afternoon. Indeed discussions continued while cruising along the Seine and while dining at the top of the Tour Montparnasse. However, the vitality and usefulness of even the most successful meeting is difficult to transmit by the printed word.
Author: Helmut König
Publisher: Springer Science & Business Media
ISBN: 364205062X
Category : Science
Languages : en
Pages : 518
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Book Description
Microbial cell wall structures play a significant role in maintaining cells’ shape, as protecting layers against harmful agents, in cell adhesion and in positive and negative biological activities with host cells. All prokaryotes, whether they are bacteria or archaea, rely on their surface polymers for these multiple functions. Their surfaces serve as the indispensable primary interfaces between the cell and its surroundings, often mediating or catalyzing important interactions. Prokaryotic Cell Wall Compounds summarizes the current state of knowledge on the prokaryotic cell wall. Topics concerning bacterial and archaeal polymeric cell wall structures, biological activities, growth and inhibition, cell wall interactions and the applications of cell wall components, especially in the field of nanobiotechnology, are presented.
Author: Jonathan Robert Herrmann
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Surface layers (S-layers) are nanoporous shells of crystalline protein surrounding a great diversity of bacteria and nearly all known archaea. As the outermost component of the cell envelope, S-layers are one of the most abundant biopolymers on earth and are implicated in functions ranging from providing the structural integrity of the cell to mediating host-pathogen interactions. In this thesis, I report a multi-scale analysis of S-layers from the model bacterium Caulobacter crescentus and a more recently cultivated thaumarchaeote, Nitrosoarchaeum limnia. By first biophysically characterizing the S-layer protein (SLP) from C. crescentus, RsaA, I discovered that environmental calcium mediates multiple physical states of the S-layer. I leveraged this knowledge to reconstitute and specifically image S-layer assembly in living cells. Super-resolution fluorescence microscopy and single-molecule tracking demonstrated that remarkably fast and efficient continuous 2D protein crystallization governs S-layer self-assembly. I further examined the rapid 2D crystallization of RsaA using a combination of time-resolved small angle x-ray scattering (SAXS) and electron cryo-microscopy (Cryo-EM). These observations revealed that a multi-step crystallization pathway involving a short-lived crystalline intermediate is responsible for rapid self-assembly of RsaA. Robust S-layer lattice formation has implications for essential cell functions such as energy production, which in the ammonia-oxidizing archaeaon N. limnia likely occurs within the pseudo-periplasmic space between the cell's only lipid membrane and the extracellular S-layer. Electrodiffusion simulations of the N. limnia cell envelope suggest that the S-layer facilitates diffusion of its main energy source, ammonium ions, through the nanopores of the S-layer by creating a charged protein surface. As such, we propose ion transport as an evolutionary basis for conservation of charged amino acids among archaeal SLPs. Taken together, these findings inform the development of antibiotics mediating S-layer biology and provide insight into possible avenues to design biologically inspired self-assembling macromolecular nanomaterials.
Author: Linda Bruslind
Publisher:
ISBN:
Category : Biology
Languages : en
Pages : 0
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Book Description
Welcome to the wonderful world of microbiology! Yay! So. What is microbiology? If we break the word down it translates to "the study of small life," where the small life refers to microorganisms or microbes. But who are the microbes? And how small are they? Generally microbes can be divided in to two categories: the cellular microbes (or organisms) and the acellular microbes (or agents). In the cellular camp we have the bacteria, the archaea, the fungi, and the protists (a bit of a grab bag composed of algae, protozoa, slime molds, and water molds). Cellular microbes can be either unicellular, where one cell is the entire organism, or multicellular, where hundreds, thousands or even billions of cells can make up the entire organism. In the acellular camp we have the viruses and other infectious agents, such as prions and viroids. In this textbook the focus will be on the bacteria and archaea (traditionally known as the "prokaryotes,") and the viruses and other acellular agents.
