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Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 81
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Book Description
An improved controlled-release arthropod repellent formulation for topical application to a person's exposed skin areas that provides extended protection against biting arthropods, which is safe and agreeable to use, which is more compatible with other and projected military materials and systems than the Army's current 75% N, N-diethyl m-toluamide (DEET) in alcohol formulation and which complies with the registration requirements of the Environmental Protection Agency (EPA) has been developed in Phase I and Phase II of this contract. The Phase II repellent containing 35% DEET and an acrylate polymer has been refined to improve its low temperature stability. This new Phase III formulation was the basis for the EPA insect repellent registration submitted on May 27, 1987. The acrylate polymer used in the repellent formulation had to be scaled-up first. A few problems were encountered but they were overcome and the polymer was prepared successfully in the required quantity. A technical data package covering the production processes, quality control and product specification was written for the Insect/Arthropod Repellent Lotion.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 81
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Book Description
An improved controlled-release arthropod repellent formulation for topical application to a person's exposed skin areas that provides extended protection against biting arthropods, which is safe and agreeable to use, which is more compatible with other and projected military materials and systems than the Army's current 75% N, N-diethyl m-toluamide (DEET) in alcohol formulation and which complies with the registration requirements of the Environmental Protection Agency (EPA) has been developed in Phase I and Phase II of this contract. The Phase II repellent containing 35% DEET and an acrylate polymer has been refined to improve its low temperature stability. This new Phase III formulation was the basis for the EPA insect repellent registration submitted on May 27, 1987. The acrylate polymer used in the repellent formulation had to be scaled-up first. A few problems were encountered but they were overcome and the polymer was prepared successfully in the required quantity. A technical data package covering the production processes, quality control and product specification was written for the Insect/Arthropod Repellent Lotion.
Author: Thomas R. Tice
Publisher:
ISBN:
Category :
Languages : en
Pages : 297
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Book Description
To better protect military personnel from insect bites and from the health problems associated with insect bites, the Army would like an improved insect-repellent formulation using N, N-diethyl-m-tolulamide (DEET) as the active ingredient. The improved formulation should be efficacious for a longer period of time than repellent formulations that are presently available. And, the improved formulation should have properties that would encourage military personnel to use it. The objective of this research program was to develop a long-acting, arthropod, repellent formulation that was efficacious for 12 hours. Several approaches were examined to afford a formulation that released DEET at a controlled rate. These approaches involved encapsulation techniques and included a variety of microcapsule preparations and film-forming preparations. A formulation consisting of 53% DEET and 47% inert ingredients showed improved efficacy over the repellent the Army is presently using. This improved formulation contained encapsulated and free DEET. Efficacy results from human testing with mosquitos demonstrated that the improved repellent formulation is significantly more effective for a longer period of time than the repellent the Army presently uses (75% DEET in ethanol). In addition to the development and evaluation of the improved repellant formulation, a unique trim package was designed and constructed for the formulation. Important technical improvements were made to measure the in vitro rate of evaporation of conventional and controlled-release repellents.
Author: E. S. Nuwayser
Publisher:
ISBN:
Category :
Languages : en
Pages : 177
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Book Description
The overall objective of Phase II is to bring the prototype sustained release arthropod repellent formulation developed in Phase I to large scale manufacturing stage. This Phase II report details the work conducted during the past eight months for the development of a 12 hour sustained action arthropod repellent formulation. The work culminated in the development of BIOTEK sustained action Formulation 50I which meets virtually all the criteria and requirements of the contract; and the manufacture and submission to USAMRDC of 2,600 samples of the formulation in camouflaged and non-camouflaged labelled containers for evaluation. In addition an EPA Registration Package, a User Training Manual, and a Technical Data Package were prepared and submitted to the Army. Extensive evaluation of BIOTEK Formulation 50I was conducted: 1) in vitro on weanling pig skin 2) in vivo on human volunteers under controlled environments against a variety of mosquitoes; 3) in vivo on human volunteers in field test in Vero Bleach Florida against a variety of mosquitoes; 4) in rabbits against a variety of arthropods; 5) in rabbits to determine toxicity; and 6) for compatability with military materials. Troop Acceptability of the formulation was also determined on human volunteers of military age.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 354
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Book Description
Between 1 May and 15 August 1986 field tests involving human subjects and natural mosquito populations were conducted at the Florida Medical Entomology Laboratory, University of Florida IFAS Field Station in Vero Beach, Florida on 3 slow release insect repellent formulations of deet (N, N-diethyl-m-tolumaide developed by BIOTEK, Inc. of Woburn, Massachusetts. These field tests were funded by a BIOTEK subcontract from a U.S. Army Grant awarded for the development and testing of a slow release insect repellent formulations. The work scope for these field tests included these objectives: 1) Preparation of protocol for field tests of BIOTEK's sustained action arthropod repellent utilizing Aedes taeniorhynchus and Anopheles quadrimaculatus; 2) Recruitment of subjects and personnel for the field tests; 3) To conduct pre-test sampling of mosquito populations at potential field sites and then decide on the appropriate site for each of the field tests; and 4) To conduct tests with humans of three (3) BIOTEK slow release arthropod repellent formulations and a deet standard utilizing field populations of Aedes Taeniorhynchus and Anopheles quadrimaculatus during the interval 30 June to 18 August 1986.
Author: Neil A. Randen
Publisher:
ISBN:
Category :
Languages : en
Pages : 260
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Book Description
An improved controlled-release arthropod repellent formulation for topical application to a person's exposed skin areas that provides extended protection against biting arthropods, which is safe and agreeable to use, which is more compatible with other current and projected military materials and systems than the Army's current 75% N, N-diethyl-m-toluamide (DEET) in alcohol formulation and which compiles with the registration requirements of the Environmental Protection Agency (EPA) has been developed. The Phase I formulation containing 30% DEET and an acrylate polymer served as the starting point for the refinement and development in Phase II. The final Phase II submission contained 35% DEET and the acrylate polymer. This formulation provided 95% repellency against Aedes aegypti mosquitoes for 14-15 hours, 10-11 hours and 14015 hours when evaluated in the constant high humidity, the variable high humidity and the basic hot climatic conditions using a modified standard mosquito repellency test method (ASTM:E951-83).
Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 566
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Book Description
Author: Joel Coats
Publisher: Academic Press
ISBN: 0323854125
Category : Nature
Languages : en
Pages : 360
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Book Description
Advances in Arthropod Repellents offers the most current knowledge on arthropod repellents. This area of study is quickly evolving as mosquito- and tick-borne diseases become more prevalent worldwide. Written by global arthropod repellent experts, this book begins by delving into molecule discovery and assay development that is followed by the latest research and investigations of repellent developments and effects. The book then offers readers a look into the global field, semi-field, and laboratory trials using various insect repellents, ranging from Africa, Australia, Europe, South America and the United States. Lastly, it examines the future of spatial repellents and expert insight. This book is a valuable resource for entomologists and vector control researchers and practitioners. Public health officials and developers in private pest control companies, as well as readers in academia will find this a useful resource to learn the latest information available on controlling the spread of arthropod-borne diseases with repellents. Discusses recent progress on understanding how insect repellents work, as well as modern methods for finding new molecules and formulations Edited by a team whose expertise includes cutting-edge insect repellent research and development Serves as a reference and resource that will be useful to a wide variety of professionals, particularly those in public health and vector control
Author: Armed Forces Pest Management Board
Publisher: Lulu.com
ISBN: 1105053377
Category : Science
Languages : en
Pages : 69
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Book Description
This Technical Guide provides preventive medicine information and guidance to personnel who may come into contact with nuisance or disease-carrying arthropods (disease vectors), or who are responsible for protecting the health of personnel. It describes techniques that provide maximum, safe protection from arthropod attack. These techniques include the use of protective clothing and equipment, repellents, pesticides, and other strategies. Originally published by the U.S. Army.
Author: Mustapha Debboun
Publisher: CRC Press
ISBN: 1420006657
Category : Medical
Languages : en
Pages : 526
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Book Description
Drawing together information previously found only in articles, reviews, symposia proceedings, commercial literature, and medical entomology texts, Insect Repellents: Principles, Methods, and Uses is a one-volume source on the development, evaluation, and use of repellents. It provides a thoughtful analysis of old and new information, from t
Author:
Publisher: Government Printing Office
ISBN: 9780160873119
Category : Medical
Languages : en
Pages : 728
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Book Description
Textbooks of Military Medicine. Patrick Kelley, specialty editor. Explores the various natural and manmade challenges faced by today's soldier upon mobilization and deployment. Offers comprehensive research on a range of topics related to preventive medicine, including a historic perspective on the principles of military preventive medicine, national mobilization and training, preparation for deployment, and occupational and environmental issues during sustainment.
