Author: Leslie Ann Silver
Publisher:
ISBN:
Category :
Languages : en
Pages : 134
Book Description
Context-dependent Function of Delta, a Neurogenic Gene, During Development of Drosophila Melanogaster
Author: Leslie Ann Silver
Publisher:
ISBN:
Category :
Languages : en
Pages : 134
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 134
Book Description
Structural and Functional Analyses of Delta, an EGF-homologous Neurogenic Gene, During Development of Drosophila Melanogaster
Author: Pamela Jaai Kooh
Publisher:
ISBN:
Category :
Languages : en
Pages : 388
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 388
Book Description
Structural and Functional Analysis of Delta, an EGF-homologous Neurogenic Gene, During Development of Drosophila Melanogaster
Author: Pamela Jaai Kooh
Publisher:
ISBN:
Category :
Languages : en
Pages : 346
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 346
Book Description
The Role of the Neurogenic Genes Notch and Delta in Vertebrate Retinal Cell Determination
Author: Richard I. Dorsky
Publisher:
ISBN:
Category :
Languages : en
Pages : 142
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 142
Book Description
A Molecular Characterization of the Drosophila Neurogenic Gene Delta
Author: Casey Casimir Kopczynski
Publisher:
ISBN:
Category :
Languages : en
Pages : 360
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 360
Book Description
Molecular Mechanisms of Notch Signaling
Author: Tilman Borggrefe
Publisher: Springer
ISBN: 3319895125
Category : Science
Languages : en
Pages : 417
Book Description
This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a useful resource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.
Publisher: Springer
ISBN: 3319895125
Category : Science
Languages : en
Pages : 417
Book Description
This book describes the Notch signaling pathway with a focus on molecular mechanisms. The Notch signaling pathway is a seemingly simple pathway that does not involve any second messenger. Upon ligand binding two consecutive proteolytic cleavages of the NOTCH receptor release the Notch intracellular domain from the membrane. The Notch intracellular domain migrates into the nucleus and activates gene expression. Recently, new technologies allowed us to better understand this pivotal signaling cascade and revealed new regulatory mechanisms. The different chapters cover many aspects of the Notch signaling focusing on the mechanisms governing the receptor/ligand interaction as well as on the downstream intracellular signaling events. Aspects of both canonical and non-canonical signaling are discussed and the function of Notch signaling in physiological and pathological contexts are elucidated. This book is not only intended for experts but it should also be a useful resource for young, sprouting scientists or interested scientists from other research areas, who may use this book as a stimulating starting point for further discoveries and developments.
Drosophila Eye Development
Author: Kevin Moses
Publisher: Springer Science & Business Media
ISBN: 9783540425908
Category : Medical
Languages : en
Pages : 296
Book Description
1 Kevin Moses It is now 25 years since the study of the development of the compound eye in Drosophila really began with a classic paper (Ready et al. 1976). In 1864, August Weismann published a monograph on the development of Diptera and included some beautiful drawings of the developing imaginal discs (Weismann 1864). One of these is the first description of the third instar eye disc in which Weismann drew a vertical line separating a posterior domain that included a regular pattern of clustered cells from an anterior domain without such a pattern. Weismann suggested that these clusters were the precursors of the adult ommatidia and that the line marks the anterior edge of the eye. In his first suggestion he was absolutely correct - in his second he was wrong. The vertical line shown was not the anterior edge of the eye, but the anterior edge of a moving wave of patterning and cell type specification that 112 years later (1976) Ready, Hansen and Benzer would name the "morphogenetic furrow". While it is too late to hear from August Weismann, it is a particular pleasure to be able to include a chapter in this Volume from the first author of that 1976 paper: Don Ready! These past 25 years have seen an astonishing explosion in the study of the fly eye (see Fig.
Publisher: Springer Science & Business Media
ISBN: 9783540425908
Category : Medical
Languages : en
Pages : 296
Book Description
1 Kevin Moses It is now 25 years since the study of the development of the compound eye in Drosophila really began with a classic paper (Ready et al. 1976). In 1864, August Weismann published a monograph on the development of Diptera and included some beautiful drawings of the developing imaginal discs (Weismann 1864). One of these is the first description of the third instar eye disc in which Weismann drew a vertical line separating a posterior domain that included a regular pattern of clustered cells from an anterior domain without such a pattern. Weismann suggested that these clusters were the precursors of the adult ommatidia and that the line marks the anterior edge of the eye. In his first suggestion he was absolutely correct - in his second he was wrong. The vertical line shown was not the anterior edge of the eye, but the anterior edge of a moving wave of patterning and cell type specification that 112 years later (1976) Ready, Hansen and Benzer would name the "morphogenetic furrow". While it is too late to hear from August Weismann, it is a particular pleasure to be able to include a chapter in this Volume from the first author of that 1976 paper: Don Ready! These past 25 years have seen an astonishing explosion in the study of the fly eye (see Fig.
Muscle Development in Drosophilia
Author: Helen Sink
Publisher: Springer Science & Business Media
ISBN: 9780387300535
Category : Science
Languages : en
Pages : 224
Book Description
The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.
Publisher: Springer Science & Business Media
ISBN: 9780387300535
Category : Science
Languages : en
Pages : 224
Book Description
The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.
The Analysis of a Case of Continuous Variation in Drosophila by a Study of Its Linkage Relations ...
Author: John Smith Dexter
Publisher:
ISBN:
Category : Animals
Languages : en
Pages : 58
Book Description
Publisher:
ISBN:
Category : Animals
Languages : en
Pages : 58
Book Description
The Embryonic Development of Drosophila melanogaster
Author: Jose A. Campos-Ortega
Publisher: Springer Science & Business Media
ISBN: 3662024543
Category : Science
Languages : en
Pages : 237
Book Description
" . . . but our knowledge is so weak that no philosoph er will ever be able to completely explore the nature of even a fly . . . " * Thornas Aquinas "In Syrnbolurn Apostolorum" 079 RSV p/96 This is a monograph on embryogenesis of the fruit fly Drosophi la melanogaster conceived as a reference book on morphology of embryonie development. A monograph of this extent and con tent is not yet available in the literature of Drosophila embryolo gy, and we believe that there is areal need for it. Thanks to the progress achieved during the last ten years in the fields of devel opmental and molecular genetics, work on Drosophila develop ment has considerably expanded creating an even greater need for the information that we present here. Our own interest for wildtype embryonie development arose several years ago, when we began to study the development of mutants. While those studies were going on we repeatedly had occasion to state in sufficiencies in the existing literature about the embryology of the wildtype, so that we undertook investigating many of these problems by ourselves. Convinced that several of our colleagues will have encountered similar difficulties we decided to publish the present monograph. Although not expressely recorded, Thomas Aquinas probably referred to the domestic fly and not to the fruit fly. Irrespective of which fly he meant, however, we know that Thomas was right in any case.
Publisher: Springer Science & Business Media
ISBN: 3662024543
Category : Science
Languages : en
Pages : 237
Book Description
" . . . but our knowledge is so weak that no philosoph er will ever be able to completely explore the nature of even a fly . . . " * Thornas Aquinas "In Syrnbolurn Apostolorum" 079 RSV p/96 This is a monograph on embryogenesis of the fruit fly Drosophi la melanogaster conceived as a reference book on morphology of embryonie development. A monograph of this extent and con tent is not yet available in the literature of Drosophila embryolo gy, and we believe that there is areal need for it. Thanks to the progress achieved during the last ten years in the fields of devel opmental and molecular genetics, work on Drosophila develop ment has considerably expanded creating an even greater need for the information that we present here. Our own interest for wildtype embryonie development arose several years ago, when we began to study the development of mutants. While those studies were going on we repeatedly had occasion to state in sufficiencies in the existing literature about the embryology of the wildtype, so that we undertook investigating many of these problems by ourselves. Convinced that several of our colleagues will have encountered similar difficulties we decided to publish the present monograph. Although not expressely recorded, Thomas Aquinas probably referred to the domestic fly and not to the fruit fly. Irrespective of which fly he meant, however, we know that Thomas was right in any case.