Author: Nathan Michael Hoffman
Publisher:
ISBN:
Category :
Languages : en
Pages : 303
Book Description
Digital mass spectrometry offers the promise of unlimited mass range and enhanced functionality with existing instrument designs. The theoretical fundamentals of ion handling with digital waveforms have been well-established in the literature. Unfortunately, the lack of practical methods of implementing this theory is corroborated by the lack of publications describing analyses performed using digital mass spectrometry. The work contained herein describes methods of digital ion handling, the digital manipulation of ion stability, methods of controlling digital mass spectrometers, and digital waveform generation using microcontroller-based systems. The trapping of ions produced by laser ablation of aerosol particles is characterized as a function of various ion trap operating parameters. Three methods of low-voltage waveform generation providing a wide range of duty cycle resolution are discussed. The use of microcontrollers and analog-to-digital conversion for data acquisition is also covered in detail. Digital mass spectrometry is poised to expand the mass range of analysis by providing more capable instrumentation at lower cost than is achievable with current sinusoidal waveform technology. This work provides detailed descriptions of the practical methods by which this transition to digital mass spectrometry will be implemented down to the level of microcontroller firmware and hardware schematics.
Construction of a Digitally Operated Aerosol Laser Ablation Ion Trap Time-of-Flight Mass Spectrometer
Author: Nathan Michael Hoffman
Publisher:
ISBN:
Category :
Languages : en
Pages : 303
Book Description
Digital mass spectrometry offers the promise of unlimited mass range and enhanced functionality with existing instrument designs. The theoretical fundamentals of ion handling with digital waveforms have been well-established in the literature. Unfortunately, the lack of practical methods of implementing this theory is corroborated by the lack of publications describing analyses performed using digital mass spectrometry. The work contained herein describes methods of digital ion handling, the digital manipulation of ion stability, methods of controlling digital mass spectrometers, and digital waveform generation using microcontroller-based systems. The trapping of ions produced by laser ablation of aerosol particles is characterized as a function of various ion trap operating parameters. Three methods of low-voltage waveform generation providing a wide range of duty cycle resolution are discussed. The use of microcontrollers and analog-to-digital conversion for data acquisition is also covered in detail. Digital mass spectrometry is poised to expand the mass range of analysis by providing more capable instrumentation at lower cost than is achievable with current sinusoidal waveform technology. This work provides detailed descriptions of the practical methods by which this transition to digital mass spectrometry will be implemented down to the level of microcontroller firmware and hardware schematics.
Publisher:
ISBN:
Category :
Languages : en
Pages : 303
Book Description
Digital mass spectrometry offers the promise of unlimited mass range and enhanced functionality with existing instrument designs. The theoretical fundamentals of ion handling with digital waveforms have been well-established in the literature. Unfortunately, the lack of practical methods of implementing this theory is corroborated by the lack of publications describing analyses performed using digital mass spectrometry. The work contained herein describes methods of digital ion handling, the digital manipulation of ion stability, methods of controlling digital mass spectrometers, and digital waveform generation using microcontroller-based systems. The trapping of ions produced by laser ablation of aerosol particles is characterized as a function of various ion trap operating parameters. Three methods of low-voltage waveform generation providing a wide range of duty cycle resolution are discussed. The use of microcontrollers and analog-to-digital conversion for data acquisition is also covered in detail. Digital mass spectrometry is poised to expand the mass range of analysis by providing more capable instrumentation at lower cost than is achievable with current sinusoidal waveform technology. This work provides detailed descriptions of the practical methods by which this transition to digital mass spectrometry will be implemented down to the level of microcontroller firmware and hardware schematics.
Design and Construction of a Laser Ablation Ion Source for the CMU Penning Trap Mass Spectrometer
Author:
Publisher:
ISBN:
Category : Ion sources
Languages : en
Pages : 122
Book Description
Publisher:
ISBN:
Category : Ion sources
Languages : en
Pages : 122
Book Description
Design, Construction and Development of a Laser Desorption Ionization/laser Ablation Time-of-flight Mass Spectrometer for Chemical Analysis with and Without Surface Plasmon Resonance
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
The Design and Construction of an Aerosol Time-of-flight Mass Spectrometer for Ambient Aerosol Analysis
Author: Trent Eric Nordmeyer
Publisher:
ISBN:
Category : Aerosols
Languages : en
Pages : 468
Book Description
Publisher:
ISBN:
Category : Aerosols
Languages : en
Pages : 468
Book Description
Development of Mass Spectrometric Systems to Analyse the Result of Laser Ablation Experiments on Nano- and Microparticles
Author: Albert Pegus
Publisher:
ISBN:
Category :
Languages : en
Pages : 344
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 344
Book Description
The Design and Construction of an Ion Trap Based System for Laser Pyrolysis/Mass Spectrometry of Single Organic Aerosol Particles
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 15
Book Description
This report describes the development of particle introduction techniques to support a 3 year program for analysis of single bacteria via laser pyrolysis/mass spectrometry. Results of an investigation into various sample introduction techniques are discussed including the highly successful quasi- electrospray introduction method using a suspension of particles in methanol. Particles from .9 to 13 um have been levitated at pressures down to 10-7 torr, and mass spectrometry pressures of 10-3 torr have been obtained in less than 10 min from particle. The effectiveness of these techniques for particle introduction, pump down and stabilization has exceeded of the authors expectations and gives a positive prognosis for efforts to perform initial laser pyrolysis/mass spectrometry experiments in the year 2 effort.
Publisher:
ISBN:
Category :
Languages : en
Pages : 15
Book Description
This report describes the development of particle introduction techniques to support a 3 year program for analysis of single bacteria via laser pyrolysis/mass spectrometry. Results of an investigation into various sample introduction techniques are discussed including the highly successful quasi- electrospray introduction method using a suspension of particles in methanol. Particles from .9 to 13 um have been levitated at pressures down to 10-7 torr, and mass spectrometry pressures of 10-3 torr have been obtained in less than 10 min from particle. The effectiveness of these techniques for particle introduction, pump down and stabilization has exceeded of the authors expectations and gives a positive prognosis for efforts to perform initial laser pyrolysis/mass spectrometry experiments in the year 2 effort.
Laser Ablation Ion-storage Time-of-flight Mass Spectrometry
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 5
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 5
Book Description
Direct Laser Ablation and Ionization of Solids for Chemical Analysis by Mass Spectrometry
Author: J. K. Holt
Publisher:
ISBN:
Category :
Languages : en
Pages : 8
Book Description
A laser ablation/ionization mass spectrometer system is described for the direct chemical analysis of solids. An Nd:YAG laser is used for ablation and ionization of the sample in a quadrupole ion trap operated in an ion-storage (IS) mode that is coupled with a reflectron time-of-flight mass spectrometer (TOF-MS). Single pulse experiments have demonstrated simultaneous detection of up to 14 elements present in glasses in the ppm range. However, detection of the components has produced non-stoichiometric results due to difference in ionization potentials and fractionation effects. Time-of-flight secondary ionization mass spectrometry (TOF-SIMS) was used to spatially map elemental species on the surface and provide further evidence of fractionation effects. Resolution (m/Dm) of 1500 and detection limits of approximately 10 pg have been achieved with a single laser pulse. The system configuration and related operating principles for accurately measuring low concentrations of isotopes are described.
Publisher:
ISBN:
Category :
Languages : en
Pages : 8
Book Description
A laser ablation/ionization mass spectrometer system is described for the direct chemical analysis of solids. An Nd:YAG laser is used for ablation and ionization of the sample in a quadrupole ion trap operated in an ion-storage (IS) mode that is coupled with a reflectron time-of-flight mass spectrometer (TOF-MS). Single pulse experiments have demonstrated simultaneous detection of up to 14 elements present in glasses in the ppm range. However, detection of the components has produced non-stoichiometric results due to difference in ionization potentials and fractionation effects. Time-of-flight secondary ionization mass spectrometry (TOF-SIMS) was used to spatially map elemental species on the surface and provide further evidence of fractionation effects. Resolution (m/Dm) of 1500 and detection limits of approximately 10 pg have been achieved with a single laser pulse. The system configuration and related operating principles for accurately measuring low concentrations of isotopes are described.
Construction and Evaluation of a Pulsed Glow Discharge Time of Flight Mass Spectrometer for Real Time Chemical Speciation Analysis and for Direct Solid Sampling Using Laser Ablation
Author: Daniel Jan Fliegel
Publisher:
ISBN:
Category :
Languages : en
Pages : 251
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 251
Book Description
Direct Chemical Analysis of Solids by Laser Ablation in an Ion-Storage Time-of-Flight Mass Spectrometer
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 18
Book Description
A laser ablation/ionization mass spectrometer system is described for the direct analysis of solids, particles, and fibers. The system uses a quadrupole ion trap operated in an ion-storage (IS) mode, coupled with a reflectron time-of-flight mass spectrometer (TOF-MS). The sample is inserted radially into the ring electrode and an imaging system allows direct viewing and selected analysis of the sample. Measurements identified trace contaminants of Ag, Sn, and Sb in a Pb target with single laser-shot experiments. Resolution (m/[mu]m) of 1500 and detection limits of approximately 10 pg have been achieved with a single laser pulse. The system configuration and related operating principles for accurately measuring low concentrations of isotopes are described.
Publisher:
ISBN:
Category :
Languages : en
Pages : 18
Book Description
A laser ablation/ionization mass spectrometer system is described for the direct analysis of solids, particles, and fibers. The system uses a quadrupole ion trap operated in an ion-storage (IS) mode, coupled with a reflectron time-of-flight mass spectrometer (TOF-MS). The sample is inserted radially into the ring electrode and an imaging system allows direct viewing and selected analysis of the sample. Measurements identified trace contaminants of Ag, Sn, and Sb in a Pb target with single laser-shot experiments. Resolution (m/[mu]m) of 1500 and detection limits of approximately 10 pg have been achieved with a single laser pulse. The system configuration and related operating principles for accurately measuring low concentrations of isotopes are described.