Conceptual Modelling in Computational Immunology

Conceptual Modelling in Computational Immunology PDF Author: Martina Husáková
Publisher: Tomáš Bruckner
ISBN: 8087924029
Category : Computers
Languages : en
Pages : 174

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Book Description
Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.

Conceptual Modelling in Computational Immunology

Conceptual Modelling in Computational Immunology PDF Author: Martina Husáková
Publisher: Tomáš Bruckner
ISBN: 8087924029
Category : Computers
Languages : en
Pages : 174

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Book Description
Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.

Modeling in Computational Biology and Biomedicine

Modeling in Computational Biology and Biomedicine PDF Author: Frédéric Cazals
Publisher: Springer Science & Business Media
ISBN: 364231208X
Category : Mathematics
Languages : en
Pages : 333

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Book Description
Computational biology, mathematical biology, biology and biomedicine are currently undergoing spectacular progresses due to a synergy between technological advances and inputs from physics, chemistry, mathematics, statistics and computer science. The goal of this book is to evidence this synergy by describing selected developments in the following fields: bioinformatics, biomedicine and neuroscience. This work is unique in two respects - first, by the variety and scales of systems studied and second, by its presentation: Each chapter provides the biological or medical context, follows up with mathematical or algorithmic developments triggered by a specific problem and concludes with one or two success stories, namely new insights gained thanks to these methodological developments. It also highlights some unsolved and outstanding theoretical questions, with a potentially high impact on these disciplines. Two communities will be particularly interested in this book. The first one is the vast community of applied mathematicians and computer scientists, whose interests should be captured by the added value generated by the application of advanced concepts and algorithms to challenging biological or medical problems. The second is the equally vast community of biologists. Whether scientists or engineers, they will find in this book a clear and self-contained account of concepts and techniques from mathematics and computer science, together with success stories on their favorite systems. The variety of systems described represents a panoply of complementary conceptual tools. On a practical level, the resources listed at the end of each chapter (databases, software) offer invaluable support for getting started on a specific topic in the fields of biomedicine, bioinformatics and neuroscience.

Computational Collective Intelligence

Computational Collective Intelligence PDF Author: Manuel Núñez
Publisher: Springer
ISBN: 3319243063
Category : Computers
Languages : en
Pages : 668

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Book Description
This two-volume set (LNAI 9329 and LNAI 9330) constitutes the refereed proceedings of the 7th International Conference on Collective Intelligence, ICCCI 2014, held in Madrid, Spain, in September 2015. The 110 full papers presented were carefully reviewed and selected from 186 submissions. They are organized in topical sections such as multi-agent systems; social networks and NLP; sentiment analysis; computational intelligence and games; ontologies and information extraction; formal methods and simulation; neural networks, SMT and MIS; collective intelligence in Web systems – Web systems analysis; computational swarm intelligence; cooperative strategies for decision making and optimization; advanced networking and security technologies; IT in biomedicine; collective computational intelligence in educational context; science intelligence and data analysis; computational intelligence in financial markets; ensemble learning; big data mining and searching.

Computational Immunology

Computational Immunology PDF Author: Josep Bassaganya-Riera
Publisher: Academic Press
ISBN: 0128037156
Category : Medical
Languages : en
Pages : 212

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Book Description
Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. - Offers case studies with different levels of complexity - Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills - Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting

New Trends in Intelligent Information and Database Systems

New Trends in Intelligent Information and Database Systems PDF Author: Dariusz Barbucha
Publisher: Springer
ISBN: 331916211X
Category : Technology & Engineering
Languages : en
Pages : 381

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Book Description
Intelligent information and database systems are two closely related subfields of modern computer science which have been known for over thirty years. They focus on the integration of artificial intelligence and classic database technologies to create the class of next generation information systems. The book focuses on new trends in intelligent information and database systems and discusses topics addressed to the foundations and principles of data, information, and knowledge models, methodologies for intelligent information and database systems analysis, design, and implementation, their validation, maintenance and evolution. They cover a broad spectrum of research topics discussed both from the practical and theoretical points of view such as: intelligent information retrieval, natural language processing, semantic web, social networks, machine learning, knowledge discovery, data mining, uncertainty management and reasoning under uncertainty, intelligent optimization techniques in information systems, security in databases systems, and multimedia data analysis. Intelligent information systems and their applications in business, medicine and industry, database systems applications, and intelligent internet systems are also presented and discussed in the book. The book consists of 38 chapters based on original works presented during the 7th Asian Conference on Intelligent Information and Database Systems (ACIIDS 2015) held on 23–25 March 2015 in Bali, Indonesia. The book is divided into six parts related to Advanced Machine Learning and Data Mining, Intelligent Computational Methods in Information Systems, Semantic Web, Social Networks and Recommendation Systems, Cloud Computing and Intelligent Internet Systems, Knowledge and Language Processing, and Intelligent Information and Database Systems: Applications.

Advances in Bioinformatics and Computational Biology

Advances in Bioinformatics and Computational Biology PDF Author: Osmar Norberto de Souza
Publisher: Springer Science & Business Media
ISBN: 3642228240
Category : Computers
Languages : en
Pages : 93

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Book Description
This book constitutes the proceedings of the 6th Brazilian Symposium on Bioinformatics, BSB 2011, held in Brasília, Brazil, in August 2011. The 8 full papers and 4 extended abstracts presented were carefully peer-reviewed and selected for inclusion in this book. The BSB topics of interest cover many areas of bioinformatics that range from theoretical aspects of problems in bioinformatics to applications in molecular biology, biochemistry, genetics, and associated subjects.

The Ontology of Physics for Biology

The Ontology of Physics for Biology PDF Author: Daniel L. Cook
Publisher: CRC Press
ISBN: 0429892330
Category : Science
Languages : en
Pages : 241

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Book Description
This book introduces semantic representations of multiscale, multidomain physiological systems that link to qualitative reasoning and to quantitative analysis of biophysical processes in health and disease. Two major public health problems, diabetes and hypertension, serve as use-cases to illustrate the depth and rigor of such representations for logical inference and quantitative analysis. Central to this approach is the Ontology of Physics for Biology (OPB) that formally represents the foundations of classical physics and engineering system dynamics that are the basis for our understanding of biomedical entities, processes, and functional relationships. Furthermore, we introduce OPB-based software for annotating and abstracting available biosimulation models for reuse, recombination, and for archiving of physics-based biomedical knowledge. We have formalized and leveraged physics-based biological knowledge as a working view of physiology and biophysics from three distinct perspectives: (1) biologists and biomedical investigators, (2) biophysicists and bioengineers, and (3) biomedical ontologists and informaticists. We present a logical and intuitive semantics of classical physics as a tool for mediating and translating biophysical knowledge among biomedical domains. Daniel L. Cook, MD, PhD John H. Gennari, PhD Maxwell L. Neal, PhD

Complex Systems and Computational Biology Approaches to Acute Inflammation

Complex Systems and Computational Biology Approaches to Acute Inflammation PDF Author: Yoram Vodovotz
Publisher: Springer Nature
ISBN: 3030565106
Category : Medical
Languages : en
Pages : 307

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Book Description
This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.

Personalized Learning

Personalized Learning PDF Author: Simon Cheung
Publisher: Taylor & Francis
ISBN: 1000983870
Category : Education
Languages : en
Pages : 187

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Book Description
This self-contained monograph reports the recent approaches, methods and practices of technology-enabled personalized learning. It serves to provide some useful references for researchers and practitioners in the field in conceptualizing and deploying personalized learning. Personalized learning emphasizes student-centred learning that addresses individual learning strengths, needs, skills, and interests, and allows flexibility in the learning mode, process, time and space, where students can take ownership of their learning. It has been practiced in educational institutions at both K-12 and higher education level and, as evident from several successful cases, is an enabler of personalized learning. Educational technology incorporated with other forms of innovative pedagogical practices, such as blended learning, makes personalized learning a reality to achieve its aims effectively and efficiently. This book begins with a critical review on the features and trends of personalized learning. This is followed by a number of case studies on personalized learning practices with promising results. The latest research findings on the approaches, methods and strategies on design and implementation of personalized learning are then reported. Lastly, the prospects of personalized learning are discussed. All these provide some useful references for researchers and practitioners in the field in conceptualizing and deploying personalized learning. Personalized Learning will be a key resource for academics, researchers, and advanced students of education, instructional design and technology, educational research, educational technology, research methods, STEM Education, information and communications technology, and curriculum and instruction. The chapters included in this book were originally published as a special issue of Interactive Learning Environments.

An Introduction to Computational Systems Biology

An Introduction to Computational Systems Biology PDF Author: Karthik Raman
Publisher: CRC Press
ISBN: 0429944527
Category : Computers
Languages : en
Pages : 359

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Book Description
This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks—a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields. Key Features: A hands-on approach to modelling Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models Thoughtful exercises to test and enable understanding of concepts State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design Emphasis on coding and software tools for systems biology Companion website featuring lecture videos, figure slides, codes, supplementary exercises, further reading, and appendices: https://ramanlab.github.io/SysBioBook/ An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others.