Comprehensive Insights into Mitral Valve Prolapse: From biology to future perspectives of treatment, passing through diagnostic tools, surgical techniques and transcatheter options

Comprehensive Insights into Mitral Valve Prolapse: From biology to future perspectives of treatment, passing through diagnostic tools, surgical techniques and transcatheter options PDF Author: Christophe Tribouilloy
Publisher: Frontiers Media SA
ISBN: 2832531644
Category : Medical
Languages : en
Pages : 153

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Book Description
Mitral valve prolapse (MVP), consisting of an abnormal protrusion of mitral leaflets into the left atrium, is the main cause of severe mitral regurgitation and it often requires surgical or interventional correction. It mainly represents a typical adult disease with an average prevalence in industrialized countries ranging from 2 to 8%, but even the pediatric population may be affected showing specific features concerning both anatomy and treatment. Although its existence and clinical characteristics are known for several decades, every aspect of this pathological condition is in continuous evolution, being the subject of biologists’, cardiologists’ and surgeons’ active research. The aim of the present Research Topic is to address the MVP entity in its completeness, trying to describe all actual knowledge concerning molecular mechanisms, different clinical presentations (fibroelastic degeneration in elderly people or Barlow disease in young patients), diagnostic findings and tools (mainly represented by echocardiography and Nuclear Magnetic Resonance), their specific application to newly developed transcatheter and minimally invasive treatments, indications, surgical management and interventional strategies. For all these big chapters, special attention will be addressed to show temporal knowledge evolution and new elements acquisition, since the central message is that MVP is in flux and far from full comprehension.

Comprehensive Insights into Mitral Valve Prolapse: From biology to future perspectives of treatment, passing through diagnostic tools, surgical techniques and transcatheter options

Comprehensive Insights into Mitral Valve Prolapse: From biology to future perspectives of treatment, passing through diagnostic tools, surgical techniques and transcatheter options PDF Author: Christophe Tribouilloy
Publisher: Frontiers Media SA
ISBN: 2832531644
Category : Medical
Languages : en
Pages : 153

Get Book

Book Description
Mitral valve prolapse (MVP), consisting of an abnormal protrusion of mitral leaflets into the left atrium, is the main cause of severe mitral regurgitation and it often requires surgical or interventional correction. It mainly represents a typical adult disease with an average prevalence in industrialized countries ranging from 2 to 8%, but even the pediatric population may be affected showing specific features concerning both anatomy and treatment. Although its existence and clinical characteristics are known for several decades, every aspect of this pathological condition is in continuous evolution, being the subject of biologists’, cardiologists’ and surgeons’ active research. The aim of the present Research Topic is to address the MVP entity in its completeness, trying to describe all actual knowledge concerning molecular mechanisms, different clinical presentations (fibroelastic degeneration in elderly people or Barlow disease in young patients), diagnostic findings and tools (mainly represented by echocardiography and Nuclear Magnetic Resonance), their specific application to newly developed transcatheter and minimally invasive treatments, indications, surgical management and interventional strategies. For all these big chapters, special attention will be addressed to show temporal knowledge evolution and new elements acquisition, since the central message is that MVP is in flux and far from full comprehension.

Mitral Valve Disease

Mitral Valve Disease PDF Author: Richard R. Heuser
Publisher: Nova Biomedical Books
ISBN: 9781619423091
Category : Mitral valve insufficiency
Languages : en
Pages : 0

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Book Description
This book discusses the different aspects of mitral regurgitation as well as diagnostic and imaging studies to evaluate the patients at risk. Treatment options for patients with mitral regurgitation are discussed including some of the new non-surgical treatments. Various medical devices and technologies have evolved recently making the traditional surgery not the only option in these patients. This book will be helpful to surgeons, cardiologists, as well as other clinicians and students interested in the diagnosis and treatment of mitral regurgitation.

Cardiology Research and Clinical Developments

Cardiology Research and Clinical Developments PDF Author: Richard R. Heuser
Publisher: Nova Science Publishers
ISBN: 9781619423145
Category : Mitral valve insufficiency
Languages : en
Pages : 178

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Book Description
This book discusses the different aspects of mitral regurgitation as well as diagnostic and imaging studies to evaluate the patients at risk. Treatment options for patients with mitral regurgitation are discussed including some of the new non-surgical treatments. Various medical devices and technologies have evolved recently making the traditional surgery not the only option in these patients. This book will be helpful to surgeons, cardiologists, as well as other clinicians and students interested in the diagnosis and treatment of mitral regurgitation.

Organ Tissue Engineering

Organ Tissue Engineering PDF Author: Daniel Eberli
Publisher: Springer
ISBN: 9783030442101
Category : Technology & Engineering
Languages : en
Pages : 0

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Book Description
The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.

The ESC Textbook of Cardiovascular Medicine

The ESC Textbook of Cardiovascular Medicine PDF Author: A. John Camm
Publisher:
ISBN: 9780198824879
Category : Cardiology
Languages : en
Pages : 3198

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Book Description


Aortic Dissection and Related Syndromes

Aortic Dissection and Related Syndromes PDF Author: Ragavendra Baliga
Publisher: Springer Science & Business Media
ISBN: 0387360018
Category : Medical
Languages : en
Pages : 363

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Book Description
This state-of the-art publication is a result of the combined efforts of participants from the International Registry of Aortic Dissection (IRAD). It is the most comprehensive reference on aortic dissection The book has been divided into sections. Each chapter provides a succinct overview of the current clinical literature and incorporates illustrations for further explanation.

Aortopathy

Aortopathy PDF Author: Koichiro Niwa
Publisher: Springer
ISBN: 4431560718
Category : Medical
Languages : en
Pages : 333

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Book Description
This is the first textbook to focus on Aortopathy, a new clinical concept for a form of vasculopathy. The first section of the book starts from discussing general concept and history of Aortopathy, and then deals with its pathophysiology, manifestation, intrinsic factor, clinical implication, management and prevention. The second part closely looks at various disorders of the Aortopathy such as bicuspid aortic valve and coarctation of aorta. The book editors have published a lot of works on the topic and have been collecting relating data in the field of congenital heart disease for the past 20 years, thus present the book with confidence. The topic - an association of aortic pathophysiological abnormality, aortic dilation and aorto-left ventricular interaction - is getting more and more attention among cardiovascular physicians. This is the first book to refer for cardiologists, pediatric cardiologists, surgeons, ACHD specialists, etc. to acquire thorough knowledge on Aortopathy.

Transcatheter Mitral Valve Therapies

Transcatheter Mitral Valve Therapies PDF Author: Ron Waksman
Publisher: John Wiley & Sons
ISBN: 1119490685
Category : Medical
Languages : en
Pages : 402

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Book Description
TRANSCATHETER MITRAL VALVE THERAPIES An essential survey of the advancing field of transcatheter mitral valve repair and replacement Minimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat’s most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapy—though they are getting closer and closer to this goal. Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement’s widespread adoption, the book’s international group of contributors discuss the improvements to be made in repair and replacement procedures, as well as the adjunctive use of imaging and pharmacologic therapies. This ground-breaking text: Provides detailed explanations of transcatheter repair, transcatheter replacement, and adjunctive procedures Features chapters on the use of imaging to aid in patient selection, procedure planning, and intra-operative guidance Discusses the importance of minimally invasive approaches for mitral valve repair Examines anticoagulation following transcatheter mitral valve interventions Outlines the possible future of transcatheter mitral valve therapy Transcatheter Mitral Valve Therapies is an important, up-to-date resource for interventional cardiologists, as well as all clinical researchers and practitioners seeking information on this vital and developing treatment.

Transcatheter Paravalvular Leak Closure

Transcatheter Paravalvular Leak Closure PDF Author: Grzegorz Smolka
Publisher: Springer
ISBN: 9811054002
Category : Medical
Languages : en
Pages : 182

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Book Description
Representing the first book to offer complete coverage of all related topics, this title provides up-to-date guidance on exactly why, when, and how to perform transcatheter paravalvular leak closure. An international panel of leading experts in the field address the entire spectrum of associated problems, from relevant anatomy, to imaging methods, to implantation techniques, to a comprehensive presentation of clinical data. Specific topics covered in this book include the mechanisms of artificial valve dehiscence, with a focus on local anatomical conditions; data on conservative and surgical treatment; qualification for paravalvular leak closure; multimodality imaging techniques; a step-by-step description of access, device selection and implantation; practical tips and tricks for troubleshooting; and the latest clinical data on transcatheter paravalvular leak closure. The book facilitates the application of contemporary knowledge in clinical cardiology, cardiac surgery, imaging and interventional cardiology in the management of patients with this challenging clinical problem.

Infective Endocarditis

Infective Endocarditis PDF Author: Gilbert Habib
Publisher: Springer
ISBN: 3319324322
Category : Medical
Languages : en
Pages : 330

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Book Description
This reference resource represents the consensus opinion a team of international specialists on the diagnosis and treatment of infective endocarditis (IE), many of whom have been co-authors of American or European guidelines on the topic. It is therefore a useful tool for many practitioners: cardiologists and cardiac imagers, cardiac surgeons, echocardiographers, specialists of internal medicine, neurologists, and infectiologists. ​​​Infective endocarditis (IE) is defined as an infection of the endocardial surface of the heart, which may include one or more heart valves, the mural endocardium, or a septal defect. Its intracardiac effects include severe valvular insufficiency, which may lead to intractable congestive heart failure and myocardial abscesses. If left untreated, IE is generally fatal. IE is a changing disease with new diagnostic techniques, new therapeutic strategies, more frequent elderly people and patients with prosthetic valves of intravenous drug users.