Community Series in Resident Memory T Cells: Guardians of the Balance of Local Immunity and Pathology, Volume II PDF Download
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Author: Nick P. Goplen
Publisher: Frontiers Media SA
ISBN: 2832550525
Category : Medical
Languages : en
Pages : 136
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Book Description
As we learn more about the intricacies of immune interactions, the goalposts of ideal vaccination strategies change. It has become apparent that for many pathogens, immunizations should seek to optimize lymphocyte-mediated protection at their portals of entry, which is not likely to be accomplished with current intramuscular jabs. However, there are increased reports suggesting resident memory CD4 and CD8 T cells may, or indeed do, cause pathologies in the lung, gut, skin, pancreas, CNS, and adipose tissue. This is following chronic infection, immunization, or sensitization and it is becoming clearer that protective immunity ought to be finely balanced with the pathogenic capacity of the resident cells providing the immunity. Alternatively, in instances like asthma or inflammatory bowel disease (IBD) where the bulk of resident CD4 or CD8T cells’ pathogenic capacity is not restrained, understanding the mechanisms of escape from immune regulation may be key. Thus we are interested in soliciting works that seek to provide a deeper mechanistic understanding of the balance of immunity and pathology that local resident memory T cells must successfully display in order to build upon the existing dogma regarding ideal vaccination strategies.
Author: Nick P. Goplen
Publisher: Frontiers Media SA
ISBN: 2832550525
Category : Medical
Languages : en
Pages : 136
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Book Description
As we learn more about the intricacies of immune interactions, the goalposts of ideal vaccination strategies change. It has become apparent that for many pathogens, immunizations should seek to optimize lymphocyte-mediated protection at their portals of entry, which is not likely to be accomplished with current intramuscular jabs. However, there are increased reports suggesting resident memory CD4 and CD8 T cells may, or indeed do, cause pathologies in the lung, gut, skin, pancreas, CNS, and adipose tissue. This is following chronic infection, immunization, or sensitization and it is becoming clearer that protective immunity ought to be finely balanced with the pathogenic capacity of the resident cells providing the immunity. Alternatively, in instances like asthma or inflammatory bowel disease (IBD) where the bulk of resident CD4 or CD8T cells’ pathogenic capacity is not restrained, understanding the mechanisms of escape from immune regulation may be key. Thus we are interested in soliciting works that seek to provide a deeper mechanistic understanding of the balance of immunity and pathology that local resident memory T cells must successfully display in order to build upon the existing dogma regarding ideal vaccination strategies.
Author: Nick P. Goplen
Publisher: Frontiers Media SA
ISBN: 2889715485
Category : Medical
Languages : en
Pages : 124
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Book Description
Author: King K. Holmes
Publisher: World Bank Publications
ISBN: 1464805253
Category : Medical
Languages : en
Pages : 1027
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Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Author: Alasdair D. T. Govan
Publisher:
ISBN: 9780443056352
Category : Pathology
Languages : en
Pages : 843
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Book Description
Pathology Illustrated presents both general and systematic pathology in a highly visual style. This format makes the essential information more accessible and memorable.
Author: David Salisbury
Publisher: The Stationery Office
ISBN: 9780113225286
Category : Medical
Languages : en
Pages : 486
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Book Description
This is the third edition of this publication which contains the latest information on vaccines and vaccination procedures for all the vaccine preventable infectious diseases that may occur in the UK or in travellers going outside of the UK, particularly those immunisations that comprise the routine immunisation programme for all children from birth to adolescence. It is divided into two sections: the first section covers principles, practices and procedures, including issues of consent, contraindications, storage, distribution and disposal of vaccines, surveillance and monitoring, and the Vaccine Damage Payment Scheme; the second section covers the range of different diseases and vaccines.
Author: Christos Giannou
Publisher:
ISBN:
Category : Amputees
Languages : en
Pages : 364
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Book Description
Accompanying CD-ROM contains graphic footage of various war wound surgeries.
Author: Andrew P. Zbar
Publisher: Springer Science & Business Media
ISBN: 9781852334826
Category : Medical
Languages : en
Pages : 486
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Book Description
An understanding of the complex workings of the immune system is essential for all surgeons. Immune responses play a crucial part in the way human body reacts to infection and trauma. Immunology for Surgeons contains a high-level discussion of this difficult clinical area. The text looks at tumor immunobiology and immunotherapy as well as the worldwide results of various clinical trials. The topics discussed focus on relevant immunological and molecular biological trends for future treatment of complex surgical disease. The main objective of the text is to render a difficult area accessible for the postgraduate surgical trainee and established surgeon who is interested in immunology.
Author:
Publisher:
ISBN:
Category : Health promotion
Languages : en
Pages : 338
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Book Description
Author: Oleg Eremin
Publisher: Oxford University Press, USA
ISBN: 019958687X
Category : Medical
Languages : en
Pages : 547
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Book Description
Providing the necessary foundation for a critical understanding of this rapidly expanding area of biological science that underpins and explains the modern concepts of a wide range of diseases and conditions, this book gives a concise, readable, and up-to-date account of immunology in general and its translation into key areas of clinical practice.
Author: Joel J. Alpert
Publisher:
ISBN:
Category : Family medicine
Languages : en
Pages : 76
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Book Description
