Community Genetics in the Arabian Gulf Region

Community Genetics in the Arabian Gulf Region PDF Author: Lihadh Gazali
Publisher: S. Karger AG (Switzerland)
ISBN: 9783805578554
Category : DNA
Languages : en
Pages : 0

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Book Description
Developed from the International Genetics Congress in Dubai in December 2003, this publication discusses genetic-related topics with the aim of improving the standards in education, service and research. Special focus is given to various aspects of genetic disorders from a global perspective, and on the link between basic scientific research and clinical genetics as a bridge to community health. The contributions discuss common genetic problems in Arab countries and the Middle East, and the development of preventive strategies in this region. Consanguineous marriage is common in the Arab world. This has significant implications for increased rates of recessive disorders, lethal malformations and other disease conditions. A better understanding of the influence of endogamy and consanguinity on population structure and transmission of diseases as well as the attitudes and perception of families, societies and cultural groups towards genetic disorders and genetic counselling is thus crucial in planning educational programs, genetic counselling and screening programs. This publication is of value for all those interested in clinical genetics. Readers are updated on recent developments and global challenges in their specialist field.

Community Genetics in the Arabian Gulf Region

Community Genetics in the Arabian Gulf Region PDF Author: Lihadh Gazali
Publisher: S. Karger AG (Switzerland)
ISBN: 9783805578554
Category : DNA
Languages : en
Pages : 0

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Book Description
Developed from the International Genetics Congress in Dubai in December 2003, this publication discusses genetic-related topics with the aim of improving the standards in education, service and research. Special focus is given to various aspects of genetic disorders from a global perspective, and on the link between basic scientific research and clinical genetics as a bridge to community health. The contributions discuss common genetic problems in Arab countries and the Middle East, and the development of preventive strategies in this region. Consanguineous marriage is common in the Arab world. This has significant implications for increased rates of recessive disorders, lethal malformations and other disease conditions. A better understanding of the influence of endogamy and consanguinity on population structure and transmission of diseases as well as the attitudes and perception of families, societies and cultural groups towards genetic disorders and genetic counselling is thus crucial in planning educational programs, genetic counselling and screening programs. This publication is of value for all those interested in clinical genetics. Readers are updated on recent developments and global challenges in their specialist field.

Genetic Disorders Among Arab Populations

Genetic Disorders Among Arab Populations PDF Author: Ahmad S. Teebi
Publisher: Oxford University Press, USA
ISBN: 9780195093056
Category : Medical
Languages : en
Pages : 538

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Book Description
Few regions of the world have a more varied physiography or a richer ethnic, religious, social, and cultural mix than the Arab world. As a consequence, Arabs are genetically diverse despite their linguistic and religious cohesion. High but variable rates of inbreeding prevail in all Arab countries with numerous examples of isolates among them. These include some Bedouin groups, Nubians, Druze, Jews, and others. Arab populations have high frequencies of autosomal recessive disorders, homozygosity of autosomal dominant and X-linked traits, and a wealth of new syndromes and variants, the majority of which are autosomal recessive. Genetic disorders that cause major health problems include hemoglobinopathies, neurogenetic disorders, inherited metabolic diseases, and inborn error of morphogenesis. Because of their characteristically high prevalence, some of these disorders are considered markers for Arab populations. This book presents the unique profile of genetic disorders and variants in Arabs. In addition, it describes their unusual demographic pattern including fertility rates and other population dimensions, family structure, magnitude and effects of consanguineous marriages and indicators of health and disease. Genetic counseling and the distinctive cultural and religious attitudes towards various genetic issues are also presented. Disorders that have increased tribal occurrences or are limited to large kindreds, as well as small geographic or religious isolates, are highlighted to facilitate their recognition, study, and management.

Contemporary Bioethics

Contemporary Bioethics PDF Author: Mohammed Ali Al-Bar
Publisher: Springer
ISBN: 3319184288
Category : Medical
Languages : en
Pages : 273

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Book Description
This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-‘aql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God’s special gifts to human beings, God’s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice – the maqa' sid – which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved.

Healthcare in the Arabian Gulf and Greater Middle East: A Guide for Healthcare Professionals - E-Book

Healthcare in the Arabian Gulf and Greater Middle East: A Guide for Healthcare Professionals - E-Book PDF Author: May McCreaddie
Publisher: Elsevier Health Sciences
ISBN: 0323833578
Category : Medical
Languages : en
Pages : 214

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Book Description
Healthcare in the Arabian Gulf and Greater Middle East is the first evidence-based, English-language textbook to provide a comprehensive overview of healthcare in this region, where health systems are rapidly evolving and feature large numbers of expatriate health professionals serving a population with diverse ethnic, social, cultural and environmental needs. This unique book covers relevant research, conditions and appropriate interventions and treatment. Readers will gain an insight into the key health challenges of the region and how to approach them, as well as local healthcare structures and cultural considerations such as Islam and healthcare, culturally competent communication and the role of the family. Written by experienced international and local academics and professionals, this book will be invaluable for students, healthcare professionals and anyone interested in working in this fascinating region. Based on the latest evidence – provides a comprehensive overview of key healthcare challenges in region Features numerous Arabic contributors as well as non-Arabic contributors with experience and expertise in the region Key strategic, local and individual healthcare approaches – including a generic adaptable toolkit Short case studies and thinking grids for appropriate care Discussion of social, cultural and environmental perspectives specific to the region Easy to read and follow Highly practical – covers key topics including: Islam and healthcare pain management palliative and end of life care culturally competent communication consumer-driven healthcare the family in healthcare in the Arabian gulf communicable and non-communicable diseases

From Trucial States to United Arab Emirates

From Trucial States to United Arab Emirates PDF Author: Frauke Heard-Bey
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Genomics and Health in the Developing World

Genomics and Health in the Developing World PDF Author: Dhavendra Kumar
Publisher: Oxford University Press
ISBN: 019970547X
Category : Medical
Languages : en
Pages : 1569

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Book Description
Genomics and Health in the Developing World provides detailed and comprehensive coverage of population structures, human genomics, and genome variation--with particular emphasis on medical and health issues--in the emerging economies and countries of the developing world. With sections dedicated to fundamtals of genetics and genomics, epidemiology of human disease, biomarkers, comparative genomics, developments in translational genomic medicine, current and future health strategies related to genetic disease, and pertinent legislative and social factors, this volume highlights the importance of utilizing genetics/genomics knowledge to promote and achieve optimal health in the developing world. Grouped by geographic region, the chapters in this volume address: - Inherited disorders in the developing world, including a thorough look at genetic disorders in minority groups of every continent - The progress of diagnostic laboratory genetic testing, prenatal screening, and genetic counseling worldwide - Rising ethical and legal concerns of medical genetics in the developing world - Social, cultural, and religious issues related to genetic diseases across continents Both timely and vastly informative, this book is a unique and comprehensive resource for genetists, clinicians, and public health professionals interested in the social, ethical, economic, and legal matters associated with medical genetics in the developing world.

Genetic Disorders Among Arab Populations

Genetic Disorders Among Arab Populations PDF Author: Ahmad S. Teebi
Publisher: Springer Science & Business Media
ISBN: 3642050808
Category : Medical
Languages : en
Pages : 776

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Book Description
Arab populations have their “own” genetic disorders, both universal and particular. Genetic diversity within these source populations, along with the fact that the rates of inbreeding are often high and family sizes are often large, constitute conditions that facilitate the emergence and detection of phenotypes explained notably by autosomal recessive inheritance; in which case, the use of homozygosity gene mapping can facilitate the discovery of the corresponding genes. The present book includes 5 parts dealing with various aspects that relate to the genetic structure of Arabs and minorities within the Arab world as well as genetic disorders prevalent in this part of the world. It includes updated reviews of the genetic disorders in various Arab countries and geographic regions. The focus is primarily, but not exclusively, on the group of single-gene disorders with particular emphasis on autosomal recessive conditions. It further includes epidemiological and clinical data as well as inheritance patterns, mutation and polymorphism data, and available haplotype analysis data. The ethnic and genetic diversity of the Arab populations is discussed as well as aspects of genetic counseling practice in this region together with a proposal for an ethical framework for genetic research and prevention of genetic disorders. The target audience of this book includes human and medical geneticists, genetic counselors, researchers, medical specialists dealing with Arab patients or practicing in Arab countries, medical and genetic counseling students, and nurses.

Oil Pollution and its Environmental Impact in the Arabian Gulf Region

Oil Pollution and its Environmental Impact in the Arabian Gulf Region PDF Author: M. Al-Azab
Publisher: Elsevier
ISBN: 0080457800
Category : Science
Languages : en
Pages : 256

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Book Description
Situated within the richest oil area in the world, the Arabian Gulf represents a stressed ecosystem with scarce published data and environmental studies. The oil-related activities cause significant damages to different ecosystem components such as coral reefs, algal mats, mangrove and other habitats. In addition to the increasing potential of pollution and its adverse effect on the ecosystem, oil spills and relevant implications can severely affect the main source of desalinated water for the Gulf countries due to their limited water resources. Interest in pollution issues associated with Arabian Gulf has been growing in the last few years. These issues include identification and documentation of the major sources of oil pollution in the Gulf region, evaluation of the analytical methods used to identify the different types of pollutants, review of the recent advances in oil pollution impact treatment and prevention, develop stronger cooperation ties between interested members of the community, and encourage awareness of the oil pollution as a serious environmental problem in the region. This book compiles recent studies addressing the above issues grouped in four categories; monitoring and characterizing oil spills, modeling the fate of pollutants and oil slicks in marine water, environmental effects of oil pollution on the ecosystem components, and combating, prevention and treatment of oil pollution. * Studies oil pollution issues in association with the Arabian Gulf * Compiles recent case studies conducted in the Arabian Gulf * Addresses diverse topics related to pollution issues in the marine water in general and in the Arabian Gulf in particular

Research Ethics in the Arab Region

Research Ethics in the Arab Region PDF Author: Henry Silverman
Publisher: Springer
ISBN: 3319652664
Category : Philosophy
Languages : en
Pages : 390

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Book Description
This book addresses the pressing issues involved with the ethical conduct of research in one developing world region – the Arab Region. Clinical research has soared in the developing world -as pharmaceutical companies continue their search for regions with large, treatment naive populations - including the Arab region, and has profound implications for the health and the economies for the area. The ethical issues involved with the conduct of such research, however, have so far not been adequately addressed. This volume presents the issues regarding research ethics and research governance that have relevance for health authorities, regulators, industry, and academia. As a multi-authored volume it includes both international and local experts on ethical issues in research, representing all stakeholders, thus presenting a balanced view on this timely topic.

Gene Function

Gene Function PDF Author: S. Rosenthal
Publisher: Elsevier
ISBN: 1483188515
Category : Science
Languages : en
Pages : 565

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Book Description
Gene Function, contains the proceedings of the 12th Meeting of the Federation of European Biochemical Societies held in Dresden, Germany in 1978. The meeting provided a forum for discussing progress in the understanding of gene function and covered topics ranging from the functional organization of chromatin to principles of interactions and recognition models. The role of DNA sequence in the recognition of restriction endonucleases and modification enzymes is also examined, along with gene expression, RNA processing and modification, and isolation and synthesis of genes. Comprised of 49 chapters, this volume begins with an overview of what can be learned from the genetic analysis of the lac repressor, followed by a discussion on the topography of the interaction the lac repressor, RNA polymerase, and histones with DNA. The reader is then introduced to complementarity and recognition code between regulatory proteins and DNA; chromatin replication in vitro; and the cytoplasmic "petite" mutation in Saccharomyces cerevisiae. Subsequent chapters explore arc-like and helical arrangements of nucleosome cores; changes in gene expression during cellular differentiation; polyadenylation and processing of pre-messenger RNA; and the molecular biology of bacteriophages T3 and T7. This book will be of interest to geneticists, biochemists, and molecular biologists.