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Author: Peter. S. Borriello
Publisher: CRC Press
ISBN: 1351087614
Category : Science
Languages : en
Pages : 345
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Book Description
The aim of this book is to bring together the information available on established clostridial diseases of the gastrointestinal tract, including the more recent observations with respect to the mechanisms of action and to critically review the data available which implicate clostridia in the gastrointestinal diseases of unknown etiology such as infantile necrotizing enterocolitis and large bowl cancer. Information on the wide range of gut diseases in animals, both natural and laboratory induced, in which clostridia have been shown to be involved or are being implicated, has been included, as in many instances these observations sever to help delineate the etiologies of human disease.
Author: Peter. S. Borriello
Publisher: CRC Press
ISBN: 1351087614
Category : Science
Languages : en
Pages : 345
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Book Description
The aim of this book is to bring together the information available on established clostridial diseases of the gastrointestinal tract, including the more recent observations with respect to the mechanisms of action and to critically review the data available which implicate clostridia in the gastrointestinal diseases of unknown etiology such as infantile necrotizing enterocolitis and large bowl cancer. Information on the wide range of gut diseases in animals, both natural and laboratory induced, in which clostridia have been shown to be involved or are being implicated, has been included, as in many instances these observations sever to help delineate the etiologies of human disease.
Author: Francisco A. Uzal
Publisher: John Wiley & Sons
ISBN: 1118728408
Category : Medical
Languages : en
Pages : 356
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Book Description
Clostridial Diseases of Animals is the first book to focus on clostridial diseases in domestic and wild animals, offering a comprehensive reference on these common diseases. Provides a single resource for all aspects of clostridial diseases Presents current, comprehensive information with a focus on clinical relevance Covers each disease in depth, including etiology, epidemiology, clinics, gross pathology, histopathology, diagnostics, diagnostic criteria, prophylaxis, control, and treatment Written by the world-leading experts in the field of clostridial diseases in animals Offers photographs and summary tables to support the concepts discussed in the text and aid in recognition
Author: S. Peter Borriello
Publisher:
ISBN: 9781351070713
Category : Clostridium diseases
Languages : en
Pages : 246
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Book Description
"The aim of this book is to bring together the information available on established clostridial diseases of the gastrointestinal tract, including the more recent observations with respect to the mechanisms of action and to critically review the data available which implicate clostridia in the gastrointestinal diseases of unknown etiology such as infantile necrotizing enterocolitis and large bowl cancer. Information on the wide range of gut diseases in animals, both natural and laboratory induced, in which clostridia have been shown to be involved or are being implicated, has been included, as in many instances these observations sever to help delineate the etiologies of human disease."--Provided by publisher.
Author: S.P. Borriello
Publisher: Springer Science & Business Media
ISBN: 9400956649
Category : Medical
Languages : en
Pages : 198
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Book Description
Antimicrobial-associated diarrhea is often caused by Clostridium difficile; this disease can best be diagnosed by detection of fecal cytotoxin in a tissue culture assay and, when therapy is indicated, can be effectively treated with orally administered vancomycin. The cause of disease in most cases of antimicrobial-associated diarrhea that do not involve C. difficile is not known; fortunately, this form of diarrhea 1S usually mild. Antimicrobial-associated diarrhea may also rarely involve s. aureus and certain enteric pathogens. 37 QHAPTER 4 Qf. TECTlON. ISOLATION Al:iQ. . . IQENTlFICATlON OF CLOSTRIDIUM PIFFICILE S.P. BORRIELLO and PAULINE HONOUR Introduction 38 Detection of Co dlfflcile in stools 38 Direct methods 38 Indirect methods 39 Isolation of Co djfficjle 40 Identification of Co difflcile 44 38 DETECTION ISOLATION AND IDENTIFICATION OF CLOSTRIDIUM DIFFICILE S.P. Borriello and Pauline Honour Introduction In view of the mounting evidence generated world wide in the last few years that firmly implicates £. difficile as the aetiological agent in both antibiotic and non-antibiotic associated pseudomembranous colitis (Larson ~ al., 1978, Bartlett ~ al., 1978a, George ~ al., 1978a), and also recent recognition of the fact that there may be a spectrum of gastrointestinal diseases associated with £. difficile infections (Borriello and Larson, 1981, Bolton ~ al., 1980, Brettle ~ al., 1982), an increasing number of laboratories are seeking to detect, isolate and identify £. difficile from clinical samples.
Author: Rial D. Rolfe
Publisher: Elsevier
ISBN: 1483289052
Category : Medical
Languages : en
Pages : 427
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Book Description
Despite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated intestinal disease, many extremely important and fundamental questions remain to be answered. The objectives of this book are to summarize the available information regarding Clostridium difficile and its role in intestinal disease and to serve as a basis for future investigations in this challenging area.Clostridium difficile: its role in Intestinal Disease. An excellent volume that should appeal not only to the devotee of C difficile but to all gastroenterologists and microbiologists, this will not languish on my library shelves like so many other books I have reviewed. It will be regularly thumbed. --R.H. George, consultant microbiologist, Children's Hospital, BirminghamClostridium difficile: Its Role in Intestinal disease. The book is well written and informative; it has a vast amount of information packed in it...this book would be a welcome addition to the researchers and clinicians interested in C difficile-associated intestinal diseases. --Edward Balish, University of Wisconsin Medical School
Author: P. Gopalakrishnakone
Publisher: Springer
ISBN: 9789400758681
Category : Medical
Languages : en
Pages : 0
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Book Description
Biological toxins are an important part of our world, a reality with which we need to cope, so in parallel with understanding their mechanisms of action and thereby improving our fundamental knowledge, there are successful efforts to utilize them as therapeutics against some debilitating human and animal diseases. In view of the complexity of different types of biotoxins and the broad range of toxin structure, physiology, utility, and countermeasures including regulatory issues, it was thus aimed to compile a book on biotoxins and bioweapons. This reference work in the Toxinology handbook series gathers together knowledge from around the globe about naturally inspired and manufactured biological weapons. The authors describe how they work; how authorities may detect their presence, prevent their use, and diagnose their impacts; and the means by which medical and paramedical professionals may treat victims. Also described are how they have been used to further our knowledge and what insights they have given us into evolutionary and physiological processes. Finally, it is also discussed how these toxins can be used as therapeutics and what the implications of such therapeutics are to their use as biothreat agents. This volume provides a reference accessible to scientists, educators, and medical experts alike with an interest in biotoxins, focusing on the major toxins used as bioweapons. Regulatory agencies will also benefit from the information provided in this book. Some in the intended audience may need to understand how they elicit their effects and how we can defend ourselves against them. Others may be interested in the sometimes colorful histories that surround this subset of biotoxins that can be and, in some cases, have been used as weapons.
Author: Jean-Claude Rambaud
Publisher: Springer Science & Business Media
ISBN: 2817809246
Category : Medical
Languages : en
Pages : 143
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Book Description
Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified much earlier. A brief historical review of the discovery of the enteropathogenicity of C. difficile in man might thus be useful. The bacterium was described in 1935 in the stools of infants, using the name Bacillus difficilis [7]. Until 1977, the microorganism, renamed C. difficile, considered to be of endogenous origin, was isolated only in rare cases of abscess or infection, most often unrelated to the digestive tract. Its role in genito-urinary infections [6] was not confirmed. However, the frequency of infant healthy carriers was recognized from the outset [7, 13]. Pseudo-membranous colitis (PMC) was described in 1883 following a gastroenterostomy. Many cases of this condition were published subsequently before the antibiotic era, describing various risk factors [4]. However the disease began to flourish only with the increasingly wide use of antibiotics. Antibiotic associated PMC was first described as an enterocolitis, though with little pathological evidence. It was principally related to the use of chloramphenicol and tetracyclines and attributed to proliferation of Staphylococcus au reus [ 11], a concept strengthened by the spectacular therapeutic action of vancomycin.
Author: Saverio Peter Borriello
Publisher:
ISBN:
Category :
Languages : en
Pages : 299
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Book Description
Author: Julian I. Rood
Publisher: Academic Press
ISBN: 0080542395
Category : Science
Languages : en
Pages : 555
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Book Description
The clostridia are a group of bacteria of considerable medical and economic importance and include species responsible for generating the most potent toxins known to humans. The Clostridia: Molecular Biology and Pathogenesis is a unique work, comprising the most complete reference on the clostridia for over 20 years, bringing together the results from some of the most innovative and exciting research in the past decade. Using a principle-oriented rather than taxonomic approach, the results from molecular biology research are placed in the context of their clinical significance, and the disease process as a whole. This state-of-the-art work is truly comprehensive, covering and integrating the diverse topics of genetics, physiology, pathogenesis and cell biology. Written and edited by world-renowned authorities, material is presented to give the reader an up-to-date knowledge of the pathogenic species of this important genus. Background information is followed by details of the genetics, molecular biology, biochemistry and disease mechanisms. The structure, function and mode of action of toxins and other virulence determinants is clearly presented. As such, this work will prove essential for students, teachers, research microbiologists, infectious disease clinicians, toxin specialists, and all those working in medical or veterinary bacteriology, microbial genetics and the pharmaceutical industries. - Covers appropriate medical and veterinary topics - Contains authoritative contributions by international experts - Presents the current state of knowledge and areas for future research - Truly comprehensive--covers topics from molecular biology and physiology
Author: Jocelyn Mott
Publisher: John Wiley & Sons
ISBN: 1119376343
Category : Medical
Languages : en
Pages : 999
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Book Description
Blackwell's Five-Minute Veterinary Consult Clinical Companion: Small Animal Gastrointestinal Diseases offers a highly accessible resource for the most common and not-so common diseases of the gastrointestinal system, pancreas, liver, and gallbladder in small animals. Covers diseases and disorders of the oral cavity and salivary glands, esophagus, stomach, small intestine, colon, anus and perianal region, pancreas, liver, and gall bladder Provides a comprehensive yet concise reference to gastrointestinal and hepatologic diseases encountered in daily veterinary practice Presents the most important information for each disease in a highly accessible format Depicts the clinical conditions discussed with helpful color photographs
