Chemistry and Biology of Pteridines, 1986 PDF Download
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Author: Bernard A. Cooper
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 1088
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Book Description
Author: Bernard A. Cooper
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 1088
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Book Description
Author: June E. Ayling
Publisher: Springer Science & Business Media
ISBN: 1461529603
Category : Medical
Languages : en
Pages : 806
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Book Description
The pteridines in their multitude of forms fulfill many roles in nature ranging from pigments to cofactors for numerous redox and one-carbon transfer reactions. This extraordinary diversity of function is unified by the unique chemistry of the pteridine heterocycle. The International Symposium on the Chemistry and Biology of Pteridines and Folates is a forum for presenting recent and exciting advances in this expanding field. In of ideas results that has often stimulated bringing together various disciplines, a synergy fresh approaches to major problems. The Tenth International Symposium held at Orange Beach, Alabama, March 21-23, 1993, proved no exception by providing new insights into folate enzymology, tetrahydrobiopterin and molybdopterin biosynthesis and function, enzyme synthesis and regulation, along with novel synthetic strategies for producing compounds that will expedite further study. The many outstanding scientific contributions found in the following chapters, which represent the work presented at the Symposium, are a reflection of the significant advances made since the Ninth International Symposium held in Zurich in 1989. Since the 7th International Symposium in St. Andrews, Scotland, a tradition has evolved of honoring scientists who have made outstanding contributions to pteridine research with a Gowland Hopkins medal and lectureship. Sir Frederick Gowland Hopkins initiated the first investigation of what later proved to be pteridines in his studies of the yellow and white colors of butterflies.
Author: B. A. Cooper
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110856263
Category : Science
Languages : en
Pages : 1080
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Book Description
No detailed description available for "Montreal, Canada, June 15-20, 1986".
Author:
Publisher: Elsevier
ISBN: 0080858511
Category : Science
Languages : en
Pages : 415
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Book Description
Biological Roles and Function of Modification
Author: Hans-Christoph Curtius
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110889005
Category : Science
Languages : en
Pages : 1380
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Book Description
No detailed description available for "Zurich, Switzerland, September 3-8, 1989".
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1024
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author:
Publisher: Academic Press
ISBN: 0080866425
Category : Science
Languages : en
Pages : 413
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Book Description
Vitamins and Hormones
Author: D.E. Wilman
Publisher: Springer Science & Business Media
ISBN: 9400903979
Category : Science
Languages : en
Pages : 455
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Book Description
Walter C. J. ROSS Emeritus Professor, University of London To paraphrase a statement made by Howard E. Skipper many years ago, 'We cancer chemotherapists have often exploited and overworked our chemist colleagues and they have been conveniently forgotten at award giving times'. This book is an attempt to rectify this and highlight the contribution of the chemist in modifying the structure of various types of agent to enhance their effectiveness as inhibitors of the growth of neoplastic tissues. Cancer chemotherapy is a relatively new discipline, coming later than the introduction of sulphonamides and antibiotics. Modern anti-cancer therapy started with the report of the use of a war gas methyl-di-(2-chloroethyl)amine (HN2) in 1946 for the treatment of Hodgkin's disease. The recognition that this compound acted as a bifunctional alkylating agent under physiological conditions led to the synthesis of a wide range of drugs with similar properties. Amongst these were chlorambucil, melphalan, busulphan, and cyclophos phamide which still find use today. Somewhat later, a range of antibiotics was found to be effective, for example aminopterin (1948) and 6-mercaptopurine (1958) to treat acute leukaemias and 5-fluorouracil and 6-azauracil (1957-8) which were used against a variety of cancers. Since these early days the net has been cast ever wider and, as well as ingenious modifications of the compounds mentioned above, anticancer drugs now include growing classes of compounds ranging from purely synthetic agents to natural products. Many of these are discussed in the present book.
Author: Edgar Pick
Publisher: Academic Press
ISBN: 1483268187
Category : Medical
Languages : en
Pages : 488
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Book Description
Lymphokines: A Forum for Immunoregulatory Cell Products, Volume 14, reviews the state of knowledge on lymphokines. The book opens with an integrative view of the role of lymphokines in the generation of fever. It stresses that pirogenicity is the attribute of more than one lymphokine: interleukin 1 (IL-1), interferon a, and tumor necrosis factor (TNF) all possess this quality. This is followed by separate chapters on the chemistry of IL-1 molecules and cloning of the gene for human monocyte IL-1; the production of lymphokine by cells of the central nervous system; the acute phase plasma protein response studied at the level of gene structure and expression; and the involvement of calcium and calcium-linked enzymes in T cell proliferation. Subsequent chapters deal with the involvement of pteridines in T cell activation; the discovery of cachectin and the establishment of its identity with TNF; the effect of IFN-? and several cytotoxic cytokines on the proliferation, differentiation, and function of normal and leukemic myeloid cells; and the cytotoxic lymphokines produced by effector T cells. The final chapter discusses the ways in which chemically defined changes in cell membranes affect cell division.
Author: Wolfgang Pfleiderer
Publisher: Wiley-Blackwell
ISBN:
Category : Science
Languages : en
Pages : 928
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Book Description
These papers are the proceedings of the International Symposium on the Chemistry and Biology of Pteridines and Folates. The book brings together contributions from some 250 scientists from chemistry, biochemistry, biology, pharmacology, and medicine to present and discuss recent advances in this expanding field.
