Chemical Mutagenesis in Laboratory Mammals

Chemical Mutagenesis in Laboratory Mammals PDF Author: Environmental Mutagen Information Center (U.S.)
Publisher:
ISBN:
Category : Chemical mutagenesis
Languages : en
Pages :

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Chemical Mutagenesis in Laboratory Mammals

Chemical Mutagenesis in Laboratory Mammals PDF Author: Environmental Mutagen Information Center (U.S.)
Publisher:
ISBN:
Category : Chemical mutagenesis
Languages : en
Pages :

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Book Description


Chemical Mutagenesis in Laboratory Mammals

Chemical Mutagenesis in Laboratory Mammals PDF Author:
Publisher:
ISBN:
Category : Chemical mutagenesis
Languages : en
Pages : 164

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Book Description
Over 350 references to books and journal articles published during 1928-1973. Also covers foreign-language literature. Arranged under citation index, Agent index, Chemical abstracts registry number index, Organism index, KWIC index, Author index, First author index, and Addendum. Entries in Citation index and First author index provide essential bibliographical information.

Chemical Mutagenesis in Laboratory Mammals

Chemical Mutagenesis in Laboratory Mammals PDF Author: Environmental Mutagen Information Center (U.S.)
Publisher:
ISBN:
Category : Chemical mutagenesis
Languages : en
Pages : 105

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Book Description
Over 650 references; mostly journal articles dating from the 1960's to 1975. Also includes foreign-language literature. Arranged under Citation index, Agent index, Chemical abstracts service registry number index, Taxonomic index, Test object index, Mammalian germ cell assay systems index, Author index, and KWIC index. Entry in Citation index gives bibliographical information.

Chemical Mutagenesis in Mammals and Man

Chemical Mutagenesis in Mammals and Man PDF Author: F Vogel (Ed)
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 556

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The Role of Mammals in the Future of Chemical Mutagenesis Research

The Role of Mammals in the Future of Chemical Mutagenesis Research PDF Author: W. L. Russell
Publisher:
ISBN:
Category : Mutagenesis
Languages : en
Pages : 13

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Mutagenesis in Sub-Mammalian Systems

Mutagenesis in Sub-Mammalian Systems PDF Author: G.E. Paget
Publisher: Springer Science & Business Media
ISBN: 9401166390
Category : Medical
Languages : en
Pages : 234

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Book Description
Topics in Toxicology Toxicology is a science that stands at the intersection of several interests and disciplines. These intersecting forces are by no means all scientific since some are legal and some are commercial. All have valid things to say about the conduct and interpretation of toxicity experiments. The practising toxicologist must bear all these sometimes conflicting forces in mind as he carries out his duties. This is especially true, of course, of the toxicologist in industry. Toxicology is also a field in which contract research particularly flourishes and a number of major contract research companies have established over the years a reputation for contributing usefully to the practice of this skill. These contract research organisations are particu larly favoured to develop an appreciation of the problems of the industrial toxicologist, since it is very common for such a company to service the toxicological needs of companies in several sectors of industry producing new chemical compounds, and the contract research company, therefore, is aware of a wider diversity of problems than probably affects a single toxicologist in one industry.

Comparative Chemical Mutagenesis

Comparative Chemical Mutagenesis PDF Author: Frederick De Serres
Publisher: Springer Science & Business Media
ISBN: 1461334098
Category : Science
Languages : en
Pages : 1113

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Book Description
Frederick J. de Serres, Ph. D. Office of the Associate Director for Genetics National Institute of Environmental Health Sciences Research Triangle Park, North Carolina (U. S. A. ) 27709 The Workshop on Comparative Chemical Mutagenesis was orga nized to begin the process of problem identification and resolution concerning our needs to evaluate the data on test chemicals arising from assays for mutagenic activity on laboratory organisms. In the past, data on chemical mutagens has been generated and published in the scientific literature on a more or less random basis. Individual chemicals enjoy a brief period of "popularity" that leads to a burst of publications in the same or sometimes related assay systems. The incompleteness of the data base, in many of these cases, makes comparative mutagenesis difficult or impossible. In our attempts to compare the genetic effects of a given chemical over a wide range of assay systems, we are often interested in making quantitative as well as qualitative compari sons. To restate the first comparison: is the chemical under ques tion a weak, moderate or potent mutagen over a wide range of assay systems--or alternatively, does the level of response vary markedly? To make the second comparison, what is needed is information on the spectrum of genetic alterations produced as well as whether this spectrum is consistent over a wide range of organisms.

Mutagenesis of the Mouse Genome

Mutagenesis of the Mouse Genome PDF Author: Monica Justice
Publisher: Springer Science & Business Media
ISBN: 1402050577
Category : Science
Languages : en
Pages : 98

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Book Description
The Second Georgia Genetics Symposium was held color. Soon after, he joined the sta? of The Jackson in September 2000, and the development of this Laboratory in Bar Harbor, Maine. book took place over the nearly 4 years that ensued. Much of Bill’s research at the lab was centered During this time, many advances in the Genome around investigating phenotypic variability within Project and mouse mutagenesis were made. In the highly inbred strains, and in that connection he book overview, we discuss the development of the developed the technique of ovarian transplanta- Genome Project (which is the context for the sym- tion (even using embryonic donors) and a genetic posium), the role the mouse was playing at that scheme whereby graft compatibility could be time, how that role has evolved, and how the combined with the ability to distinguish o?spring chapters of the book address issues in mouse func- from donor and regenerated host ovaries. His tional genetics. Many of the chapters in this book work was in?uenced by the second World War, will provide useful resources for years to come. ?rst because The Jackson Laboratory turned into Of greater impact, our keynote speaker, the a production colony for the military, primarily to mutagenesis pioneer William L. (Bill) Russell, produce mice for typhoid testing, and secondly, passed away on July 23, 2003.

Mutagenicity: Assays and Applications

Mutagenicity: Assays and Applications PDF Author: Ashutosh Kumar
Publisher: Academic Press
ISBN: 0128092602
Category : Science
Languages : en
Pages : 352

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Book Description
Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment. Chapters focused on specific types of mutagens or testing methods for their detection collectively explore the current state of human and environmental mutagenesis, future perspectives and regulatory needs. The test procedures for measuring mutagenicity, their advantages and limitations are described with practical and procedural detail, along with their presentation and data processing aspects. It is an essential reference covering the breadth and depth of the field of mutagenicity studies and regulation. By providing both important introductory material and practical assays and applications, this book is useful to graduate students, academic and industry researchers and regulators at various stages of their careers, leading to improved risk assessment and regulation. Presents an up-to-date and in-depth review of the current state of mutagenesis research Draws upon the combined experience and expertise of an international group of highly respected editors and chapter authors Provides an introduction to the concept of mutagenesis with particular consideration given to novel chemicals and materials

Biologic Markers in Reproductive Toxicology

Biologic Markers in Reproductive Toxicology PDF Author: National Research Council (U.S.). Subcommittee on Reproductive and Neurodevelopmental Toxicology
Publisher: Routledge
ISBN:
Category : Medical
Languages : en
Pages : 424

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Book Description