Cellular Lipid Metabolism

Cellular Lipid Metabolism PDF Author: Christian Ehnholm
Publisher: Springer Science & Business Media
ISBN: 3642003001
Category : Medical
Languages : en
Pages : 385

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Book Description
For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.

Cellular Lipid Metabolism

Cellular Lipid Metabolism PDF Author: Christian Ehnholm
Publisher: Springer Science & Business Media
ISBN: 3642003001
Category : Medical
Languages : en
Pages : 385

Get Book

Book Description
For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.

Lipid Signaling and Metabolism

Lipid Signaling and Metabolism PDF Author: James M. Ntambi
Publisher: Academic Press
ISBN: 0128194057
Category : Science
Languages : en
Pages : 566

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Book Description
Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad spectrum of biological processes and disease states. Here, world-renowned investigators offer a basic examination of general lipid, metabolism, intracellular lipid storage and utilization that is followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics. Emphasis is placed on bioactive lipid metabolism and research that has been impacted by new technologies and their new potential to transform precision medicine. Provides a clear, up-to-date understanding of lipid signaling and metabolism and the impact of recent technologies critical to advancing new studies Empowers researchers to examine bioactive lipid signaling and metabolism, supporting translation to clinical care and precision medicine Discusses the role of lipid signaling and metabolism in obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders, among others

Anatomy and Physiology

Anatomy and Physiology PDF Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0

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Book Description


Cellular Lipid Metabolism

Cellular Lipid Metabolism PDF Author: Christian Ehnholm
Publisher: Springer
ISBN: 9783642002991
Category : Medical
Languages : en
Pages : 376

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Book Description
For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.

Fat Absorption

Fat Absorption PDF Author: Arnis Kuksis
Publisher: CRC Press
ISBN: 1351088890
Category : Medical
Languages : en
Pages : 582

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Book Description
This book provides an authoritative and comprehensive source of information on the biochemical an metabolic aspects of digestion and absorption of different dietary fats and other lipids, with minimal discussion of the physical chemistry of the process, which has been covered in great detail in previous reviews. It is intended for both researchers and practitioners in the biomedical field who require detailed knowledge of the biomedical and metabolic transformations involed in the intestinal digestion and resynthesis of dietary fats and other lipids.

The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism PDF Author: Anne Le
Publisher: Springer
ISBN: 331977736X
Category : Medical
Languages : en
Pages : 186

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Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Cellular Lipid in Health and Disease

Cellular Lipid in Health and Disease PDF Author: James Mukasa Ntambi
Publisher: Elsevier
ISBN: 0323955835
Category : Science
Languages : en
Pages : 558

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Book Description
Cellular Lipid in Health and Disease presents a comprehensive and systematic coverage of the various roles lipids play in human biology. This book is organized in four parts covering the foundational concepts of lipid biology all the way to the therapeutic opportunities they present. The first part is dedicated to the basic concepts of cellular lipid, the roles it plays in the cell, structure and physiology, regulation mechanisms, storage, and utilization. The second part is focused on lipid metabolism, covering the organelles involved in lipid trafficking, metabolism in aging, cholesterol homeostasis, lipid droplets (LDs), and lipid oxidation. Part three is dedicated to the roles lipids play in specific disease states including renal, metabolic, cardiovascular, and fatty liver diseases. Other conditions include cancer, neurodegenerative diseases, and the intricate relationship between cellular lipids and autophagy. The final part covers therapeutic opportunities, including drug carrier systems, modeling lipid metabolism, and prevention therapeutics. Cellular Lipid in Health and Disease is a complete reference targeted at graduate students and early career researchers in cell biology, biochemistry, and pharmacology. Research physicians can also benefit from the foundational content and links to pathologies and therapeutic opportunities. Offers a complete and systematic coverage of lipid biology Provides foundational content and establishes the needed connections to translational aspects of the research in this area Includes chapters on the therapeutic opportunities presented by lipids

Fat Detection

Fat Detection PDF Author: Jean-Pierre Montmayeur
Publisher: CRC Press
ISBN: 1420067761
Category : Medical
Languages : en
Pages : 646

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Book Description
Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se

Emerging Role of Lipids in Metabolism and Disease

Emerging Role of Lipids in Metabolism and Disease PDF Author: Marco Segatto
Publisher: MDPI
ISBN: 3039437011
Category : Medical
Languages : en
Pages : 308

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Book Description
Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies.

Phospholipid Metabolism in Cellular Signaling

Phospholipid Metabolism in Cellular Signaling PDF Author: Jose M. Mato
Publisher: CRC Press
ISBN: 9780849359781
Category : Medical
Languages : en
Pages : 172

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Book Description
Phospholipids are no longer considered exclusively as the building blocks of biomembranes, but are now regarded to be exceptionally important to cellular signalling. Another conclusion resulting from studies over the past several years is that no single general scheme for the role of phospholipids during cell activation can be drawn as representative of all cells. Phospholipid Metabolism in Cellular Signaling presents a comprehensive view of the recent advances made in certain major research areas within the field of phospholipid metabolism in cellular signalling. Topics discussed within this volume include lipid composition of cellular membranes and their organization in biological systems, the dynamic aspects of phospholipid metabolism and its regulation by extracellular stimuli, and the role of newly discovered glycosyl-phosphatidylinositols in insulin action . The book also discusses two biologically active phospholipids: the sphingolipids, and ether-linked glycerophospholipids (the platelet activating factor). Phospholipid Metabolism in Cellular Signaling is an important research reference that should be considered required reading by all scientists and graduate students working on cell activation (e.g., growth factors, hormones, and oncogenes).