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Author: Jorg Dietrich
Publisher: Frontiers Media SA
ISBN: 2832524044
Category : Science
Languages : en
Pages : 315
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Book Description
Author: Jorg Dietrich
Publisher: Frontiers Media SA
ISBN: 2832524044
Category : Science
Languages : en
Pages : 315
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Book Description
Author: António Salgado
Publisher: Elsevier
ISBN: 0128180854
Category : Medical
Languages : en
Pages : 712
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Book Description
Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
Author: Nicholas M Boulis
Publisher: Academic Press
ISBN: 0128025247
Category : Psychology
Languages : en
Pages : 337
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Book Description
Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig's Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. - Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases - Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance - Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy
Author: William M. Reichert
Publisher: CRC Press
ISBN: 1420009303
Category : Medical
Languages : en
Pages : 300
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Book Description
Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwel
Author: Mark H. Tuszynski
Publisher: Elsevier
ISBN: 0080529216
Category : Science
Languages : en
Pages : 713
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Book Description
CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. - The first comprehensive, authoritative volume on the topic of CNS regeneration - Reviews current therapeutic approaches - Editors and authors are experts in the field - Appeals to those interested in basic science as well as those concerned with its medical application
Author: Lijie Grace Zhang
Publisher: Springer
ISBN: 3319314335
Category : Technology & Engineering
Languages : en
Pages : 311
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Book Description
This book covers the principles of advanced 3D fabrication techniques, stem cells and biomaterials for neural engineering. Renowned contributors cover topics such as neural tissue regeneration, peripheral and central nervous system repair, brain-machine interfaces and in vitro nervous system modeling. Within these areas, focus remains on exciting and emerging technologies such as highly developed neuroprostheses and the communication channels between the brain and prostheses, enabling technologies that are beneficial for development of therapeutic interventions, advanced fabrication techniques such as 3D bioprinting, photolithography, microfluidics, and subtractive fabrication, and the engineering of implantable neural grafts.There is a strong focus on stem cells and 3D bioprinting technologies throughout the book, including working with embryonic, fetal, neonatal, and adult stem cells and a variety of sophisticated 3D bioprinting methods for neural engineering applications. There is also a strong focus on biomaterials, including various conductive biomaterials and biomimetic nanomaterials such as carbon-based nanomaterials and engineered 3D nanofibrous scaffolds for neural tissue regeneration. Finally, two chapters on in vitro nervous system models are also included, which cover this topic in the context of studying physiology and pathology of the human nervous system, and for use in drug discovery research. This is an essential book for biomedical engineers, neuroscientists, neurophysiologists, and industry professionals.
Author: Shuxin Li
Publisher: Frontiers Media SA
ISBN: 288974633X
Category : Science
Languages : en
Pages : 399
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Book Description
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030917130X
Category : Medical
Languages : en
Pages : 456
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Book Description
Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.
Author: R. Horowski
Publisher: Springer Science & Business Media
ISBN: 3709106435
Category : Medical
Languages : en
Pages : 230
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Book Description
The 10th International Winter Conference on Neurodegeneration (lWCN) has taken place from February 14-16,2002, at the lovely "SchloB Ziethen", an old prussian manor (in Prussia, 'faute de mieux', called 'SchloB', i. e. cas tle or residence). This place is 20 km off Tegel Airport, Berlin's main airport, and has been beautifully restored by baroness Edith von Thiingen (nee von BUlow, i. e. of historical Prussian aristocracy); it lends itself rather perfectly for the IWCN type of small interdisciplinary workshops on neurodegenera tion which combine short lectures with plenty of discussion. In this context, we could quote Alexander von Humboldt's famous opening words for one of the first international scientific meetings held at Berlin, on September 18, 1828: "The main purpose ... does not consist in a mutual reading of manuscripts all to be printed after at least one year in specialised publications, but in the personal communication amongst those who work in similar scientific fields; the oral and thus more stimulating exchange of ideas, might they represent facts, opinions or doubts; the foundation of friendly relations which convey illumination to our sciences, serene grace to our lives and tolerance and mildness to our habits ... Berlin, Sept. 18, 1828 Alexander von Humboldt To the IWCN aficionado, it may come as a little surprise that this is the pub lication of the 10th Winter Conference as this might mean that they must have missed number 9.
Author: Willem_M. Kühtreiber
Publisher: Springer Science & Business Media
ISBN: 1461215862
Category : Medical
Languages : en
Pages : 457
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Book Description
The concept of using encapsulation for the immunoprotection of transplanted cells was introduced for the first time in the 1960s. "[Microencapsulated cells] might be protected from destruction and from partici pation in immunological processes, while the enclosing membrane would be permeable to small molecules of specific cellular product which could then enter the general extracellular compartment of the recipient. For instance, encapsulated endocrine cells might survive and maintain an effective supply of hormone." (Chang, Ph. D. Thesis, McGill University, 1965; Chang et aI., Can J Physiol PharmacoI44:115-128, 1966). We asked Connaught Laboratories, Ltd., in Toronto to put this concept into practice. In 1980, Lim and Sun from Connaught Laboratories reported on the successful implantation of poly-I-Iysine-alginate encapsu lated rat islets into a foreign host. [Lim and Sun, Science 210:908-909, 1980]. Now many groups around the world are making tremendous progress in the encapsulation of a multitude of cell types. Kiihtreiber, Lanza, and Chick have invited many cell encapsulation groups from around the world to contribute to this book. The result is a very useful reference book in this rapidly growing area. With so many excellent au thors describing in detail the different areas of cell encapsulation, my role here will be to briefly discuss a few points.
