Catalytic Asymmetric Synthesis PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Catalytic Asymmetric Synthesis PDF full book. Access full book title Catalytic Asymmetric Synthesis by Takahiko Akiyama. Download full books in PDF and EPUB format.
Author: Takahiko Akiyama
Publisher: John Wiley & Sons
ISBN: 1119736390
Category : Science
Languages : en
Pages : 798
Get Book Here
Book Description
Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most important catalytic asymmetric reactions known today This book covers the preparation of enantiomerically pure or enriched chemical compounds by use of chiral catalyst molecules. While reviewing the most important catalytic methods for asymmetric organic synthesis, this book highlights the most important and recent developments in catalytic asymmetric synthesis. Edited by two well-qualified experts, sample topics covered in the work include: Metal catalysis, organocatalysis, photoredox catalysis, enzyme catalysis C–H bond functionalization reactions Carbon–carbon bond formation reactions, carbon–halogen bond formation reactions, hydrogenations, polymerizations, flow reactions Axially chiral compounds Retaining the best of its predecessors but now thoroughly up to date with the important and recent developments in catalytic asymmetric synthesis, the 4th edition of Catalytic Asymmetric Synthesis serves as an excellent desktop reference and text for researchers and students, from upper-level undergraduates all the way to experienced professionals in industry or academia.
Author: Takahiko Akiyama
Publisher: John Wiley & Sons
ISBN: 1119736390
Category : Science
Languages : en
Pages : 798
Get Book Here
Book Description
Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most important catalytic asymmetric reactions known today This book covers the preparation of enantiomerically pure or enriched chemical compounds by use of chiral catalyst molecules. While reviewing the most important catalytic methods for asymmetric organic synthesis, this book highlights the most important and recent developments in catalytic asymmetric synthesis. Edited by two well-qualified experts, sample topics covered in the work include: Metal catalysis, organocatalysis, photoredox catalysis, enzyme catalysis C–H bond functionalization reactions Carbon–carbon bond formation reactions, carbon–halogen bond formation reactions, hydrogenations, polymerizations, flow reactions Axially chiral compounds Retaining the best of its predecessors but now thoroughly up to date with the important and recent developments in catalytic asymmetric synthesis, the 4th edition of Catalytic Asymmetric Synthesis serves as an excellent desktop reference and text for researchers and students, from upper-level undergraduates all the way to experienced professionals in industry or academia.
Author: Aritra Sarkar
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 231
Get Book Here
Book Description
This thesis presents the mechanistic exploration of various catalytic asymmetric alkene halofunctionalization reactions. The mechanistic studies were focused on asymmetric halofunctionalization reactions that are catalyzed by the well-known, commercially available catalyst (DHQD)2PHAL. Chemical kinetics were a central part of this investigation as the study entailed exploration of various kinetic properties, such as rate law equations, effects of isotopic substitution, and competition studies, to obtain key mechanistic insights into these reactions. The kinetic studies were complemented with computational modeling that led to the proposal of detailed catalytic models. Chapter 1 introduces the inherent mechanistic challenges in a successful catalytic asymmetric alkene halofunctionalization reaction and also serves as an introduction to the kinetic tools that will be utilized in the following chapters to investigate the mechanism of the reactions. Chapter 2 presents the mechanistic investigation of (DHQD)2PHAL catalyzed asymmetric chlorolactonization of alkene carboxylic acids and illustrates the mechanistic model of catalysis for this reaction. Chapter 3 presents the mechanistic investigation of DHQD)2PHAL catalyzed asymmetric chloroetherification of alkene amides reaction. Interestingly, despite being driven by the same catalyst and chlorine source, evidences pointed to the two reactions having dramatically divergent mechanistic pictures.
Author: Koichi Mikami
Publisher: John Wiley & Sons
ISBN: 047009799X
Category : Science
Languages : en
Pages : 436
Get Book Here
Book Description
A compilation of recent advances and applications in asymmetric catalysis The field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers: * "Rational" ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond formation) * Recent findings on activation of C-H bonds, C-C bonds, and small molecules (C=O, HCN, RN=C, and CO2) and the latest developments on C-C bond reorganization, such as metathesis * Advances in "chirally economical" non-linear phenomena, racemic catalysis, and autocatalysis * Some of the recent discoveries that have led to a renaissance in the field of organocatalysis, including the development of chiral Brönstead acids and Lewis acidic metals bearing the conjugate base of the Brönstead acids as the ligands and the chiral bi-functional acid/base catalysts The book ends with a thought-provoking perspective on the future of asymmetric catalysis that addresses both the challenges and the unlimited potential in this burgeoning field. This is an authoritative, up-to-date reference for organic chemists in academia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also an excellent textbook for graduate students studying advanced organic chemistry or chemical synthesis.
Author: Giorgio Della Sala
Publisher: MDPI
ISBN: 3036509720
Category : Science
Languages : en
Pages : 172
Get Book Here
Book Description
The synthesis of enantiopure organic compounds is a key issue for several applications in pharmacology, food chemistry, agricultural chemistry, perfumery, materials science and other industrial sectors. Nowadays, asymmetric catalysis is undoubtedly the most important tool to achieve this goal. This technology, in fact, enables the production of large amounts of enantiomerically enriched compounds, employing relatively small quantities of chiral enantiopure catalysts, which is exactly what is accomplished by enzymes in nature. Since the pioneering works of Noyori, Knowles and Sharpless, which later earned them the Nobel Prize in Chemistry, asymmetric catalysis has experienced a rapid and relentless development in the last fifty years. The tremendous expansion of enantioselective transformations, the design of novel and more efficient organometallic and organic catalysts, the development of sophisticated bioreactors and cell factories, are just some of the elements responsible for such growth. However, new challenges of asymmetric catalysis are devoted to enhancing the process’s sustainability, by the introduction of recyclable and low-cost catalysts, and the use of renewable starting materials and energy source. This book provides an overview of some of these development directions and comprises a collection of review papers and a research article authored by renowned researchers actively involved in this field. The topics covered by the review papers are photoredox-catalyzed reactions of imines, asymmetric catalytic electrosynthesis, cooperative catalysis of chiral N-heterocyclic carbenes and Lewis acid, and asymmetric ring-opening reactions of epoxides catalyzed by metal–salen complexes. The research article presents a proline-catalyzed aldol reaction in water–methanol solvent mixture.
Author: Michelangelo Gruttadauria
Publisher: John Wiley & Sons
ISBN: 0470641363
Category : Science
Languages : en
Pages : 720
Get Book Here
Book Description
This book covers advances in the methods of catalytic asymmetric synthesis and their applications. Coverage moves from new materials and technologies to homogeneous metal-free catalysts and homogeneous metal catalysts. The applications of several methodologies for the synthesis of biologically active molecules are discussed. Part I addresses recent advances in new materials and technologies such as supported catalysts, supports, self-supported catalysts, chiral ionic liquids, supercritical fluids, flow reactors and microwaves related to asymmetric catalysis. Part II covers advances and milestones in organocatalytic, enzymatic and metal-based mediated asymmetric synthesis, including applications for the synthesis of biologically active molecules. Written by leading international experts, this book consists of 16 chapters with 2000 References and illustrations of 560 schemes and figures.
Author: Yi Yi
Publisher:
ISBN: 9780355890662
Category : Electronic dissertations
Languages : en
Pages : 318
Get Book Here
Book Description
Author: Armando Cordova
Publisher: John Wiley & Sons
ISBN: 3527632093
Category : Science
Languages : en
Pages : 489
Get Book Here
Book Description
This unique and long-awaited handbook on this important topic in the hot field of stereoselective organic synthesis covers several types of nucleophiles. Top international authors deal with modern forms of achieving stereoselective conjugate additions based on the use of chiral auxiliaries or asymmetric catalysis, such as P-N ligands, organocatalysis, domino reactions, Lewis acid and base catalysis. There is also a discussion of the employment of enantioselective conjugate addition transformations in total synthesis of important molecules. With its reliable and previously unpublished experimental procedures, this is a true source of high quality information.
Author: Marco Bandini
Publisher: Springer
ISBN: 3319351443
Category : Science
Languages : en
Pages : 294
Get Book Here
Book Description
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal
Author: Takahiko Akiyama
Publisher: John Wiley & Sons
ISBN: 1119736412
Category : Science
Languages : en
Pages : 798
Get Book Here
Book Description
Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most important catalytic asymmetric reactions known today This book covers the preparation of enantiomerically pure or enriched chemical compounds by use of chiral catalyst molecules. While reviewing the most important catalytic methods for asymmetric organic synthesis, this book highlights the most important and recent developments in catalytic asymmetric synthesis. Edited by two well-qualified experts, sample topics covered in the work include: Metal catalysis, organocatalysis, photoredox catalysis, enzyme catalysis C–H bond functionalization reactions Carbon–carbon bond formation reactions, carbon–halogen bond formation reactions, hydrogenations, polymerizations, flow reactions Axially chiral compounds Retaining the best of its predecessors but now thoroughly up to date with the important and recent developments in catalytic asymmetric synthesis, the 4th edition of Catalytic Asymmetric Synthesis serves as an excellent desktop reference and text for researchers and students, from upper-level undergraduates all the way to experienced professionals in industry or academia.
Author: Irishi Namboothiri
Publisher: CRC Press
ISBN: 9781003003045
Category : Science
Languages : en
Pages : 302
Get Book Here
Book Description
"Nitroalkenes have often been referred to as "synthetic chameleons" owing to their reactivity, synthetic utility and biological significance. In the last two decades, the reactivity of nitroalkenes as substrates in diverse catalytic asymmetric transformations has been of tremendous interest. This is due to the powerful electron withdrawing and co-ordinating ability of the nitro group and the amenability of the nitro group to undergo a wide variety of synthetic transformations. Although numerous original articles and reviews have appeared in the literature, a monograph providing comprehensive coverage of this topic was conspicuous by its absence. In the light of the above, this book features: A systematic, up-to-date, in-depth and well organized compilation, spread over twelve chapters, of various catalytic asymmetric reactions of nitroalkenes with diverse substrates reported till date Wide coverage of reactions such as Michael additions, Friedel-Crafts reactions, cycloadditions, asymmetric reductions, multi-component and cascade reactions as well as other miscellaneous reactions Various chiral organo-, metal- and even bio-catalysts involved in the stereoselective synthesis of multi-functional adducts via catalytic asymmetric reactions of nitroalkenes Schemes and figures detailing all the reagents, reaction conditions and product profile Mechanistic details, including transition state models, which will be useful for effective catalytic design This book will be an invaluable resource for those who are working in the area of asymmetric catalysis and synthetic methodologies"--
