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Author: Massimo Sabatini
Publisher: Springer Science & Business Media
ISBN: 1592598102
Category : Medical
Languages : en
Pages : 362
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Book Description
Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover.
Author: Massimo Sabatini
Publisher: Springer Science & Business Media
ISBN: 1592598102
Category : Medical
Languages : en
Pages : 362
Get Book Here
Book Description
Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover.
Author: Gene G Hunder
Publisher: Orient Paperbacks
ISBN: 9788122202830
Category : Family & Relationships
Languages : en
Pages : 204
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Book Description
Arthritis pain can be frustrating. And so can sorting through the various available pain relief alternatives. Mayo Clinic is dedicated to helping you live more productively and comfortably with arthritis. The book focuses on osteoarthritis and rheumatoid arthritis, but is equally valuable to people with other forms of arthritis as well. The book relies on the experience of Mayo Clinic physicians, nurses, research scientists, therapists, and other health care professionals, the ultimate aim of which is to promote self-help. This easy to read and understand book offers advice on understanding arthritis, protecting joints, exercising properly, controlling pain, healthful diet and nutrition, traveling with arthritis, and working with arthritis. The nexus between the mind and the body and the impact of emotions, stress, and relaxation is also explored in Mayo Clinic On Arthritis. The gamut of treatments existing for arthritis including medications, surgery, and alternative approaches is listed together with information on the newest treatments trends.
Author: Roland W. Moskowitz
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781767071
Category : Medical
Languages : en
Pages : 492
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Book Description
Written by the foremost experts, this text is a comprehensive clinical reference on osteoarthritis. Chapters review current information on the epidemiology, etiopathogenesis, and pathology of osteoarthritis, the biochemistry and molecular and cell biology of articular cartilage, and experimental models of osteoarthritis. Major sections focus on clinical presentations, roentgenologic and laboratory diagnosis, and treatment, including pharmacologic treatment, intra-articular therapy, surgery, arthroscopy, and complementary and alternative medicine. The authors discuss the indications, outcomes, and complications of various orthopaedic procedures. Chapters present orthopaedic approaches to osteoarthritis of various joints—the shoulder, hand, wrist, elbow, hip, knee, foot, ankle, and cervical, thoracic, and lumbar spine.
Author: J.-Y. Reginster
Publisher: Springer Science & Business Media
ISBN: 3642600263
Category : Medical
Languages : en
Pages : 790
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Book Description
Musculoskeletal diseases are rapidly becoming a major health concern. The incidence of osteoarthritis, the most common arthritic disorder, is increasing steadily due to the graying of the world population. This disease is responsible of human life, a time in for significant morbidity, particularly in the second half which the quality of life is of primary importance. The aim of this publication is to bring to physicians and scientists a comprehensive overview of the field, from molecules to men. The direct costs related to osteoarthritis have been increasing steadily over the years and will soon be comparable to those of other major illnesses, such as cardiovascular diseases. This, of course, does not take into account all of the other costs related to the disease which often cannot be simply calculated in dollars and cents. There has been a great deal of renewed interest in osteoarthritis in the last few decades. This has been brought on by the need to improve our knowledge of all aspects of the disease, especially with regard to its etiopathogenesis and treatment. The most recent findings and developments on the structural, bio chemical, biomechanical and molecular changes observed in clinical and ex perimental osteoarthritis are presented in this book.
Author: Ali Guermazi
Publisher: Clinics: Internal Medicine
ISBN: 9781437717501
Category : Medical
Languages : en
Pages : 0
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Book Description
This issue takes a multimodality approach to imaging of osteoarthritis. Clinical issues including an overview of the disease and imaging as an aid to evaluate patient functionality are also reviewed. Not only are current standards for imaging covered, but also newer techniques under development.
Author: Nigel Arden
Publisher: Springer
ISBN: 1910315168
Category : Medical
Languages : en
Pages : 99
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Book Description
This Atlas provides an up-to-date and comprehensive overview of the historical and current perspectives on osteoarthritis, including the pathophysiology and epidemiology of the disease. Written by leading authors in the field of osteoarthritis, the book discusses classification, etiology and risk factors for osteoarthritis, the disease course and determinants of osteoarthritis progression, clinical features and diagnosis as well as imaging methods to assess joint damage. The Atlas of Osteoarthritis concludes with the latest treatment updates including both nonpharmacological and pharmacological treatments, as well as surgical recommendations for patients with the disease. Osteoarthritis is the most common form of joint disease causing joint pain, stiffness, and physical disability among adults. It is an important issue for both the individual and society with its impact on public health continuing to grow as a result of the aging population, the rising prevalence of obesity, and the lack of definitive treatments to prevent or halt the progress of the disease.
Author: Sharmila Majumdar
Publisher: World Scientific
ISBN: 9814271705
Category : Medical
Languages : en
Pages : 283
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Book Description
Osteoarthritis is a condition in which low-grade inflammation results in joint pain, and it is the most common joint disease. Interactions between all of the major joint tissues, including the articular cartilage, synovium, bone marrow, subchondral bone, trabecular bone, and muscle, have been implicated in osteoarthritis. Magnetic resonance images have been used to quantify the cartilage morphology, volume and thickness, and focal defects, and may reflect changes in the biochemical composition of articular cartilage. This book brings together contributions from key investigators in the area of magnetic resonance imaging (MRI) for osteoarthritis of the knee. Written by a multidisciplinary group of scientists, engineers, and clinicians, this book is the first to cover MRI as a new emerging modality for the diagnosis of osteoarthritis, and presents new findings in both basic and clinical science research.
Author: Klaus E. Kuettner
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Health & Fitness
Languages : en
Pages : 808
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Book Description
Author: Christian Lattermann
Publisher: Springer Nature
ISBN: 3030794857
Category : Medical
Languages : en
Pages : 335
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Book Description
Early osteoarthritis is novel topic for orthopedic surgeons and its process begins immediately after joint injury. The mechanical restoration of the joint surface or ligamentous stability is not sufficient to restore the homeostatic environment in the joint, and this leads to osteoarthritis, despite mechanical stability and alignment. This book sheds light on the various mechanisms and systems involved in the gradual decline of the injured joint toward manifest osteoarthritis. Published in collaboration with ISAKOS, this volume appeals to all stakeholders in surgical orthopaedics and sports medicine.
Author: Felix Bronner
Publisher: Springer Science & Business Media
ISBN: 1846287014
Category : Medical
Languages : en
Pages : 220
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Book Description
The molecular and cellular approaches to the relationship of joint and bone problems distinguish this from other books on the topic. Advances in bone and joint biology enable practitioners to approach clinical problems more comprehensively. Emphasis on genetics and on newer viewpoints and approaches, exemplified by the possible effect of subchondral bone on osteoarthritis, gives a wider viewpoint to the reader and may enable novel approaches to solving a clinical problem.
