Cardiac Fibrosis, from Lineage Tracing to Therapeutic Application

Cardiac Fibrosis, from Lineage Tracing to Therapeutic Application PDF Author: Gianluigi Pironti
Publisher: Frontiers Media SA
ISBN: 2889665267
Category : Science
Languages : en
Pages : 164

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Book Description

Cardiac Fibrosis, from Lineage Tracing to Therapeutic Application

Cardiac Fibrosis, from Lineage Tracing to Therapeutic Application PDF Author: Gianluigi Pironti
Publisher: Frontiers Media SA
ISBN: 2889665267
Category : Science
Languages : en
Pages : 164

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Book Description


Cardiac Regeneration

Cardiac Regeneration PDF Author: Masaki Ieda
Publisher: Springer
ISBN: 3319561065
Category : Medical
Languages : en
Pages : 274

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Book Description
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Medical Applications of iPS Cells

Medical Applications of iPS Cells PDF Author: Haruhisa Inoue
Publisher: Springer
ISBN: 9811336725
Category : Medical
Languages : en
Pages : 190

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Book Description
This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells.

Cardiac Tissue Engineering

Cardiac Tissue Engineering PDF Author: Milica Radisic
Publisher: Humana Press
ISBN: 9781493910465
Category : Science
Languages : en
Pages : 0

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Book Description
Cardiac Tissue Engineering: Methods and Protocols presents a collection of protocols on cardiac tissue engineering from pioneering and leading researchers around the globe. These include methods and protocols for cell preparation, biomaterial preparation, cell seeding, and cultivation in various systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cardiac Tissue Engineering: Methods and Protocols highlights the major techniques, both experimental and computational, for the study of cardiovascular tissue engineering.

Tissue Repair and Fibrosis

Tissue Repair and Fibrosis PDF Author: Alexis Desmouliere
Publisher: Springer Science & Business Media
ISBN: 364258456X
Category : Medical
Languages : en
Pages : 358

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Book Description
With contributions by numerous experts

Heart Failure in the Child and Young Adult

Heart Failure in the Child and Young Adult PDF Author: Joseph Rossano
Publisher: Academic Press
ISBN: 0128026138
Category : Medical
Languages : en
Pages : 826

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Book Description
Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. - Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation - Combines cutting-edge research with current guidelines from the field

New Trends in Vascular Inflammation Research: From Biology to Therapy

New Trends in Vascular Inflammation Research: From Biology to Therapy PDF Author: Masanori Aikawa
Publisher: Frontiers Media SA
ISBN: 2889456374
Category :
Languages : en
Pages : 193

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Book Description


Essential Echocardiography: A Companion to Braunwald’s Heart Disease E-Book

Essential Echocardiography: A Companion to Braunwald’s Heart Disease E-Book PDF Author: Scott D. Solomon
Publisher: Elsevier Health Sciences
ISBN: 0323508723
Category : Medical
Languages : en
Pages : 594

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Book Description
Echocardiography remains the most commonly used imaging technique to visualize the heart and great vessels, and this clinically oriented text by Drs. Scott D. Solomon, Justina C. Wu, and Linda D. Gillam helps you make the most of its diagnostic and prognostic potential for your patients. Part of the highly regarded Braunwald’s family of cardiology references, Essential Echocardiography expertly covers basic principles of anatomy and physiology, the appearance of normal variants across a wide range of cardiovascular diseases, and the hands-on approaches necessary to acquire and interpret optimal echocardiographic images in the clinical setting. Abundant illustrations provide a superb visual learning experience both in print and online. Images convey clear, classic examples that represent decades of experience over multiple institutions, as well as recent advances in the field. More than 485 accompanying video clips mirror the images in the text, with easy-to-follow links from the figure citation to the video online. Each section includes one or two clinical cases that illustrate key concepts. Written by expert echocardiographers and sonographers who emphasize practical applications throughout the text, and superbly illustrated by physician-artist Dr. Bernard Bulwer. Ideal for anyone currently using or learning to use echocardiography, including cardiologists, cardiology fellows, sonographers, anesthesiologists, critical care physicians, emergency physicians, radiologists, residents, and medical students. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Heart Failure: A Companion to Braunwald's Heart Disease E-Book

Heart Failure: A Companion to Braunwald's Heart Disease E-Book PDF Author: G. Michael Felker
Publisher: Elsevier Health Sciences
ISBN: 0323609880
Category : Medical
Languages : en
Pages : 937

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Book Description
Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald's Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. - Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. - Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. - Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). - Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. - Covers the pathophysiological basis for the development and progression of heart failure. - Serves as a definitive resource to prepare for the ABIM's Heart Failure board exam. - 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition).

Cardiac Fibrosis and Heart Failure: Cause or Effect?

Cardiac Fibrosis and Heart Failure: Cause or Effect? PDF Author: Ian M.C. Dixon
Publisher: Springer
ISBN: 3319174371
Category : Science
Languages : en
Pages : 437

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Book Description
The unique biology of cardiac fibroblasts and related cells, such as cardiac myofibroblasts and valvular interstitial cells, distinguish them from other fibroblastic cells, a concept that is only beginning to be widely appreciated. Further, the natural signals that stimulate and inhibit cardiac fibrosis within these cells are not well understood. This volume compiles articles that address the molecular mechanisms that control the synthesis and secretion of the cardiac ECM. The book showcases chapters that highlight discussion of role of Transforming Growth Factor β (TGFβ), an important fibrogenic cytokine and its downstream effectors SMAD in many cardiac diseases. Further, the contributions highlight information to discuss endogenous inhibitors of cardiac fibrosis, as well as advances in tissue engineering specific to matrix in the heart. Finally, discussions of unifying mechanisms of matrix remodeling in valves and myocardium are presented. The mechanisms involved in the stimulation of cardiac fibrosis are not fully understood. In most cases the marginal attenuation of cardiac fibrosis as a result of a given therapy is a beneficial side-effect linked to other primary effects on other cells, especially cardiomyocytes. Very few drugs or agents are known to affect the function and dysfunction of cardiac fibroblasts and myofibroblasts alone. The book helps to translate the information gathered within to allow us to alter the course of fibrogenic events that are typical of cardiac fibrosis, and thereby reduce their burden on the patient and on society itself.