Cancer in Organ Transplant Recipients PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Cancer in Organ Transplant Recipients PDF full book. Access full book title Cancer in Organ Transplant Recipients by Dietrich Schmähl. Download full books in PDF and EPUB format.
Author: Dietrich Schmähl
Publisher: Springer Science & Business Media
ISBN: 3642759912
Category : Medical
Languages : en
Pages : 174
Get Book Here
Book Description
In about 5% of all organ (kidney, liver) transplant recipients, malignancies occur as a late complication of the massive immunosuppression. The malignancies are mainly skin cancers, lymphomas and renal carcinomas. The present book discusses the possible mechanisms of this type of tumorigenesis and inquires into possibilities of prevention. In particular, the described malignancies might be of viral origin. The book informs about a completely new type of carcinogenesis. Apart from the scientific aspects, it is of great practical value.
Author: A.W. Thomson
Publisher: Springer Science & Business Media
ISBN: 9401007659
Category : Medical
Languages : en
Pages : 516
Get Book Here
Book Description
Therapeutic immunosuppression has very broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (e.g., rheumatoid arthritis), skin disease, and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. In addition, products of the biotechnology industry - monoclonal antibodies, cytokines, cytokine antagonists, and other products of genetic engineering that target key molecular pathways in disease pathogenesis - have either already made, or are on the verge of making an important impact on treatment. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. Gene therapy offers considerable promise for suppressing pathogenic processes in either transplantation or autoimmune disorders. The possibility of combining these important new advances to maximize benefit to the patient, and to minimize possible untoward effects (which are also given extensive coverage in this book), is one of the most exciting challenges of contemporary medicine. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area. Each chapter is contributed by one or more experts in the field. There was a need to bring this information together in a single volume, as much of the key recent developments have been dispersed throughout the biomedical literature, largely in specialized journals. Since, as in the past, important developments in immunosuppressive therapy in one branch of medicine (i.e. transplantation) are likely to benefit another (e.g., dermatology, rheumatology, gastroenterology), cross-disciplinary coverage of the mechanistic basis of the various therapeutic strategies in a single volume is likely to convey the potential of advances in therapy in the most coherent manner possible.
Author: Somnath Mookherjee
Publisher: Springer Nature
ISBN: 3030348148
Category : Education
Languages : en
Pages : 347
Get Book Here
Book Description
This book provides teaching scripts for medical educators in internal medicine and coaches them in creating their own teaching scripts. Every year, thousands of attending internists are asked to train the next generation of physicians to master a growing body of knowledge. Formal teaching time has become increasingly limited due to rising clinical workload, medical documentation requirements, duty hour restrictions, and other time pressures. In addition, today’s physicians-in-training expect teaching sessions that deliver focused, evidence-based content that is integrated into clinical workflow. In keeping with both time pressures and trainee expectations, academic internists must be prepared to effectively and efficiently teach important diagnostic and management concepts. A teaching script is a methodical and structured plan that aids in effective teaching. The teaching scripts in this book anticipate learners’ misconceptions, highlight a limited number of teaching points, provide evidence to support the teaching points, use strategies to engage the learners, and provide a cognitive scaffold for teaching the topic that the teacher can refine over time. All divisions of internal medicine (e.g. cardiology, rheumatology, and gastroenterology) are covered and a section on undifferentiated symptom-based presentations (e.g. fatigue, fever, and unintentional weight loss) is included. This book provides well-constructed teaching scripts for commonly encountered clinical scenarios, is authored by experienced academic internists and allows the reader to either implement them directly or modify them for their own use. Each teaching script is designed to be taught in 10-15 minutes, but can be easily adjusted by the reader for longer or shorter talks. Teaching Scripts in Internal Medicine is an ideal tool for internal medicine attending physicians and trainees, as well as physician’s assistants, nurse practitioners, and all others who teach and learn internal medicine.
Author: James Neuberger
Publisher: John Wiley & Sons
ISBN: 1119633990
Category : Medical
Languages : en
Pages : 76
Get Book Here
Book Description
Explore this practical and step-by-step guide to managing liver transplant patients from leading international clinicians in Hepatology The newly revised Second Edition of Liver Transplantation: Clinical Assessment and Management delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Authors are all experts in their field and cover a world-wide perspective. Organized in an accessible, stepwise fashion and packed with text features such as key points, the book covers all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long term care. Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, learn the principles of the procedure and the long term management of the transplant recipient. Liver Transplantation provides the entire hepatology and surgical team the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks. Readers will also enjoy: A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and abuse of prognostic models An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage a patient with chronic liver disease while on the waiting list A treatment of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list A discussion of care of the liver transplant recipient after the procedure in the short and long term Perfect for gastroenterologists, hepatologists, and surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing and following liver transplantation, Liver Transplantation: Clinical Assessment and Management will also earn a place in the libraries of medical students, residents, internal medicine physicians, and GI/Hepatology trainees and all health care professionals providing clinical care to people with liver disease, before, during and after transplantation.
Author: Deborah MacFarlane
Publisher: Springer Science & Business Media
ISBN: 0387884955
Category : Medical
Languages : en
Pages : 309
Get Book Here
Book Description
The editor of Skin Cancer Management: A Practical Approach, Dr. Deborah MacFarlane, gathers experts in selected techniques related to the assessment and management of skin cancer and has them critically review the existing literature in light of their considerable experience delivering care. The authors make recommendations for the best way to perform procedures. The tables provided in each chapter then become a manual of how to perform these procedures, and may in time be adopted by the wider universe of dermatologists as the standard of performance. The detailed descriptions of technique and treatment pearls lead the novice through the sequence of events in a way that instills confidence in their ability to safely perform the procedure. An example of the painstaking expla- tions is found in Chapter 5, Intralesional and Perilesional Treatment of Skin Cancers. The reader is advised to place eye protection on the patient and those performing the injection of methotrexate into a keratoacanthoma with a central crust. Rest assured that there will be a spray or stream of methotrexate emitted from the crusted area. Having eye protection will prevent methotrexate from accidentally getting into someone’s eye. Since we all learn to assimilate new information by taking action on the recommendations that we read, it would be a good idea for the physician to create, where relevant, a checklist for each procedure in the text. The checklist can be given to the office staff to set up the equipment for the procedure.
Author: Claus Garbe
Publisher: Springer
ISBN: 9783642787737
Category : Medical
Languages : en
Pages : 440
Get Book Here
Book Description
In the past two decades, considerable interest in skin cancer has developed in the public and scientific communities. There may have been several reasons for this: - The rise in the global incidence of cutaneous cancers - New molecular biology techniques resulting in a better understanding of pathogenesis and improved diagnostic procedures - The advent of new pathological entities, e. g. , the endemic form of Kaposi's sarcoma - A constantly increasing range of therapeutic modalities, providing even more efficacious treatment and manage ment of skin cancers As N. E. Fusenig describes in the first chapter of this volume, basic research is only beginning to unravel the complex mechanism involved in cellular dedifferentiation and tumor progression. Progress is dearly needed, especially in dermato oncology, where the rise in the incidence of epithelial tumors has inflated the overall skin cancer incidence. The incidence of tumors of the skin exceeds that of all other neoplasias in humans, with recreational sun exposure being a suspected primary cause. Several studies on the effects of UV radiation have been included at the beginning of this volume. Even the role of long wavelength UV (UVA) has become a focus of research activities. The main concern is that the low carcinogenicity of UVA, in comparison to UVB, may be outweighed and exceeded in its effects by increased UV A exposure, e. g.
Author: Peter J. Morris
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 440
Get Book Here
Book Description
Author: Jörg Reichrath
Publisher: Springer Nature
ISBN: 3030462277
Category : Medical
Languages : en
Pages : 422
Get Book Here
Book Description
The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
Author: Chrysalyne D. Schmults
Publisher: Springer
ISBN: 3662470810
Category : Medical
Languages : en
Pages : 261
Get Book Here
Book Description
This book is a cutting-edge resource that provides clinicians with the up-to-date practical knowledge required in order to manage SCC patients optimally. It summarizes newly available information relating to the definition of high-risk SCC, its pathophysiologic underpinnings, and its management. New prognostic information and staging systems are summarized that enable high-risk tumors to be defined more precisely than ever before. Many helpful tips are provided on the practical management of challenging cases, including multiple tumors/field cancerization, high-risk tumors, nodal metastases, and unresectable disease. The authors are all acknowledged experts in the emerging field of high-risk and advanced SCC.
Author: Phillip Ruiz
Publisher:
ISBN: 9781107619685
Category : Transplantation immunology
Languages : en
Pages :
Get Book Here
Book Description
Modernize your approach to graft biopsies, diagnosis and pathogenesis in transplantation pathology, with the second edition of this specialized textbook. Reach the latest classification schemes, combining both anatomic and clinical pathology, and gain a comprehensive understanding of detailed pathological processes, affecting both host and graft. Following publication of the first edition in 2009, technological advances in understanding of transplant immunology and physiology have enhanced many aspects of pathological diagnoses. This edition bridges key knowledge gaps in pathophysiologic mechanisms and constantly evolving clinical protocols, facilitating strong support for the pathologist, clinician, and student. Authored by leading experts in transplantation medicine, this multimedia guide boasts richly illustrated images, underscoring vital diagnostic features for busy readers. Addressing topics such as the immunopathology of graft rejection, laboratory medicine and dermatological complications in transplantation, this textbook engages with a variety of underlying pathogeneses, taking into account current laboratory and clinical findings, worldwide.
Author: Lindsay Biga
Publisher:
ISBN: 9781955101158
Category :
Languages : en
Pages :
Get Book Here
Book Description
A version of the OpenStax text
