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Author: Nikki P. Lee
Publisher: MDPI
ISBN: 3039214632
Category : Medical
Languages : en
Pages : 146
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Book Description
Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led to discovery of molecules that have been developed into cancer biomarkers and targets. Multi-platforms for molecular characterization of tumors using next-generation genomic sequencing, immunohistochemistry, in situ hybridization, and blood-based biopsies have greatly expanded the portfolio of potential biomarkers and targets. These cancer biomarkers have been developed for diagnosis, early detection, prognosis, and prediction of treatment response. The molecular targets have been exploited for anti-cancer therapy and delivery of therapeutic agents. This Special Issue of Biomedicines focuses on recent advances in the discovery, characterization, translation, and clinical application of cancer biomarkers and targets in malignant diseases of the digestive system. The goal is to stimulate basic and translational research and clinical collaboration in this exciting field with the hope of developing strategies for prevention and early detection/diagnosis of cancer in digestive organs, and improving therapeutic and psychosocial outcomes in patients with these malignant diseases.
Author: Nikki P. Lee
Publisher: MDPI
ISBN: 3039214632
Category : Medical
Languages : en
Pages : 146
Get Book Here
Book Description
Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led to discovery of molecules that have been developed into cancer biomarkers and targets. Multi-platforms for molecular characterization of tumors using next-generation genomic sequencing, immunohistochemistry, in situ hybridization, and blood-based biopsies have greatly expanded the portfolio of potential biomarkers and targets. These cancer biomarkers have been developed for diagnosis, early detection, prognosis, and prediction of treatment response. The molecular targets have been exploited for anti-cancer therapy and delivery of therapeutic agents. This Special Issue of Biomedicines focuses on recent advances in the discovery, characterization, translation, and clinical application of cancer biomarkers and targets in malignant diseases of the digestive system. The goal is to stimulate basic and translational research and clinical collaboration in this exciting field with the hope of developing strategies for prevention and early detection/diagnosis of cancer in digestive organs, and improving therapeutic and psychosocial outcomes in patients with these malignant diseases.
Author: Nelson Yee
Publisher:
ISBN: 9783039214648
Category : Electronic books
Languages : en
Pages : 1
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Book Description
Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led to discovery of molecules that have been developed into cancer biomarkers and targets. Multi-platforms for molecular characterization of tumors using next-generation genomic sequencing, immunohistochemistry, in situ hybridization, and blood-based biopsies have greatly expanded the portfolio of potential biomarkers and targets. These cancer biomarkers have been developed for diagnosis, early detection, prognosis, and prediction of treatment response. The molecular targets have been exploited for anti-cancer therapy and delivery of therapeutic agents. This Special Issue of Biomedicines focuses on recent advances in the discovery, characterization, translation, and clinical application of cancer biomarkers and targets in malignant diseases of the digestive system. The goal is to stimulate basic and translational research and clinical collaboration in this exciting field with the hope of developing strategies for prevention and early detection/diagnosis of cancer in digestive organs, and improving therapeutic and psychosocial outcomes in patients with these malignant diseases.
Author: William B. Coleman
Publisher: Academic Press
ISBN: 0128132582
Category : Medical
Languages : en
Pages : 636
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Book Description
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: Neal C. Dalrymple, MD
Publisher: Elsevier Health Sciences
ISBN: 0323043534
Category : Medical
Languages : en
Pages : 740
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Book Description
Elsevier's new Problem Solving in Abdominal Imaging offers you a concise, practical, and instructional approach to your most common imaging questions. It presents basic principles of problem solving to apply to imaging the abdominal and pelvic organs, gastrointestinal tract, and genitourinary tract. Inside, you'll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy and percutaneous drainage. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today's best practices at your fingertips. A full-color design, including more than 700 high-quality images, highlights critical elements and compliments the text, to enhance your understanding. Best of all, a bonus CD provides you with an atlas of basic surgical procedures and survival guides for managing musculoskeletal and chest findings encountered on abdominal imaging examinations. Provides problem-solving advice to help you find abnormalities and accurately identify what you see. Presents a section devoted to clinical scenarios-organized by presenting signs or disease processes-covering those you're most likely to encounter in daily practice. Includes tips for optimization of the most common advanced imaging techniques used for the abdominal and pelvic regions-with general indications for use and special situations-to help you make the most of each modality. Offers step-by-step guidance that will help you safely approach challenging abdominal interventions, reduce complications, and improve outcomes. Features tables and boxes, tips, pitfalls, and other teaching points for easy reference. Incorporates high-quality images and a full-color design that illuminate important elements. Includes a CD containing an atlas of basic surgical procedures and survival guides for managing incidental musculoskeletal and chest findings encountered on abdominal imaging examinations.
Author: Takahiro Ochiya
Publisher: MDPI
ISBN: 3038972525
Category : Medical
Languages : en
Pages : 273
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Book Description
This book is a printed edition of the Special Issue "MicroRNAs: Novel Biomarkers and Therapeutic Targets for Human Cancers" that was published in JCM
Author: Kenneth K. W. To
Publisher: Frontiers Media SA
ISBN: 2889748596
Category : Medical
Languages : en
Pages : 188
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Book Description
Author: Michael J. Murphy
Publisher: Springer Science & Business Media
ISBN: 1607614332
Category : Medical
Languages : en
Pages : 328
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Book Description
This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.
Author: Daming Zuo
Publisher: Frontiers Media SA
ISBN: 2832511635
Category : Medical
Languages : en
Pages : 140
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Book Description
Author: Jitian Li
Publisher: Frontiers Media SA
ISBN: 2832525458
Category : Science
Languages : en
Pages : 862
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Book Description
