Boundaries between Promotion and Progression during Carcinogenesis PDF Download
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Author: Oscar Sudilovsky
Publisher: Springer Science & Business Media
ISBN: 1468459945
Category : Medical
Languages : en
Pages : 367
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Book Description
The pUrpOSE! of this conference was not to define the two areas that are being bound, which might be a well nigh impossible proposition. Rather, its focus was to concentrate on the mechanistic similarities between promotion and progression. Are the areas involved within the boundaries a continuum? Are these two simultaneous processes? Or are some of the affected cells in the stage of promotion when at the same time others have undergone irreversi ble changes tha. t position them in the stage of progression? Or are these two stages the same thing, but called by different names? To explore such concepts we assembled investigators with various back grounds and asked them to specifically address these and other questions about "The Boundaries", within the context of the session to which they con tributed. The conference lasted two and a half days, from Wednesday to Friday. There were at least four speakers per session with morning and after noon sessions each day, except on Friday when the meeting ended at noon. The first day, each speaker had 25 minutes to present a position, followed by five minutes of discussion. At the end of the session there were 40 or 50 minutes of exchange on all the issues examined. For the remaining days, there were 25 minutes of presentation and 15 minutes of discussion.
Author: Oscar Sudilovsky
Publisher: Springer Science & Business Media
ISBN: 1468459945
Category : Medical
Languages : en
Pages : 367
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Book Description
The pUrpOSE! of this conference was not to define the two areas that are being bound, which might be a well nigh impossible proposition. Rather, its focus was to concentrate on the mechanistic similarities between promotion and progression. Are the areas involved within the boundaries a continuum? Are these two simultaneous processes? Or are some of the affected cells in the stage of promotion when at the same time others have undergone irreversi ble changes tha. t position them in the stage of progression? Or are these two stages the same thing, but called by different names? To explore such concepts we assembled investigators with various back grounds and asked them to specifically address these and other questions about "The Boundaries", within the context of the session to which they con tributed. The conference lasted two and a half days, from Wednesday to Friday. There were at least four speakers per session with morning and after noon sessions each day, except on Friday when the meeting ended at noon. The first day, each speaker had 25 minutes to present a position, followed by five minutes of discussion. At the end of the session there were 40 or 50 minutes of exchange on all the issues examined. For the remaining days, there were 25 minutes of presentation and 15 minutes of discussion.
Author: National Cancer Institute (U.S.). Division of Cancer Etiology
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 550
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Book Description
Author: John Masters
Publisher: Springer Science & Business Media
ISBN: 0306468727
Category : Medical
Languages : en
Pages : 295
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Book Description
Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative of tumors at that site is naïve and misleading.
Author: Jose Russo
Publisher: World Scientific
ISBN: 9813271213
Category : Medical
Languages : en
Pages : 688
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Book Description
This narrative of a cancer researcher spans a period in which biomedicine research has been so revolutionary. The educational background and socioeconomic circumstances of the author make the story unique, shedding light on many important intellectual achievements. The author also provides an insightful view on how decisions at the upper echelon of scientific institutions affect cancer researchers. The vivid account of scientific discovery and intellectual evolution provides a fine example for the next generation of cancer researchers.
Author: Olav Hilmar Iversen
Publisher: CRC Press
ISBN: 9780891165798
Category : Medical
Languages : en
Pages : 364
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Book Description
Proceedings of an international conference held in Oslo, Aug. 1986. Topics include: philosophy of science; oncogenes; two-stage theory; aging; phenotypic cellular changes; and growth control, cell proliferation, hormonal carcinogenesis, clonality. Acidic paper. Annotation copyright Book News, Inc. Portland, Or.
Author: Sandra R. Wolman
Publisher: Springer Science & Business Media
ISBN: 1461239524
Category : Medical
Languages : en
Pages : 491
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Book Description
Seventeen cutting-edge chapters review both basic research and clinical applications of chromosomal markers of cancer. The new markers offer great promise, not only for their clinical utility in diagnosis, prognosis, and disease monitoring, but also for their contributions to a better understanding of the mechanisms of tumor development and progression. The chapters-all written by leading authorities-skillfully reveal fresh insights into the translational role of cytogenetics in identifying the cellular and molecular changes that occur in cancer. Coverage is devoted to many tissue systems-colon, breast, prostate, lung, skin, brain, and kidney-where the diagnostic and prognostic utility of chromosome markers is clearly demonstrated. A seminal book certain to become the front-line reference and authoritative resource needed by all scientists and clinicians engaged in cancer research, diagnosis, and management.
Author: Robert G. McKinnell
Publisher: Cambridge University Press
ISBN: 131658304X
Category : Science
Languages : en
Pages : 504
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Book Description
This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.
Author: National Institutes of Health (U.S.)
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 550
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Book Description
Each issue lists papers published during the preceding year.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1364
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Book Description
Author: Helmut J. Wieler
Publisher: Springer Science & Business Media
ISBN: 3642577032
Category : Medical
Languages : en
Pages : 460
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Book Description
A description of positron emission tomography in the diagnosis and management of malignant tumors. Experts from Germany and the United States present basics, technical details, and clinical aspects for both standard and new PET techniques, illustrating the importance of PET in comparison to other imaging techniques. Generously supplemented with charts, tables, and illustrations, each chapter provides readers with well-delineated descriptions, from the basic technical situation through the clinical use of PET.
