Author: Longhuo Wu
Publisher: Frontiers Media SA
ISBN: 2832500463
Category : Science
Languages : en
Pages : 254
Book Description
Bone and Cartilage Diseases – The Role and Potential of Natural Products
Author: Longhuo Wu
Publisher: Frontiers Media SA
ISBN: 2832500463
Category : Science
Languages : en
Pages : 254
Book Description
Publisher: Frontiers Media SA
ISBN: 2832500463
Category : Science
Languages : en
Pages : 254
Book Description
Bone Health and Osteoporosis
Author: United States Public Health Service
Publisher:
ISBN: 9781410219275
Category : Health & Fitness
Languages : en
Pages : 0
Book Description
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Publisher:
ISBN: 9781410219275
Category : Health & Fitness
Languages : en
Pages : 0
Book Description
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Facilitative Glucose Transporters in Articular Chondrocytes
Author: Ali Mobasheri
Publisher: Springer Science & Business Media
ISBN: 3540788999
Category : Medical
Languages : en
Pages : 96
Book Description
Articular cartilage is a highly specialized avascular connective tissue. This multidisciplinary article reviews the molecular and morphological aspects of GLUT expression and function in chondrocytes and their mesenchymal and embryonic stem cell precursors.
Publisher: Springer Science & Business Media
ISBN: 3540788999
Category : Medical
Languages : en
Pages : 96
Book Description
Articular cartilage is a highly specialized avascular connective tissue. This multidisciplinary article reviews the molecular and morphological aspects of GLUT expression and function in chondrocytes and their mesenchymal and embryonic stem cell precursors.
Bone Tissue Engineering
Author: Jeffrey O. Hollinger
Publisher: CRC Press
ISBN: 1135501912
Category : Medical
Languages : en
Pages : 462
Book Description
Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Publisher: CRC Press
ISBN: 1135501912
Category : Medical
Languages : en
Pages : 462
Book Description
Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
The Role of Natural Products in Chronic Inflammation
Author:
Publisher: Frontiers Media SA
ISBN: 2889762084
Category : Science
Languages : en
Pages : 323
Book Description
Publisher: Frontiers Media SA
ISBN: 2889762084
Category : Science
Languages : en
Pages : 323
Book Description
Pain in Osteoarthritis
Author: David T. Felson
Publisher: John Wiley & Sons
ISBN: 9780470930557
Category : Medical
Languages : en
Pages : 320
Book Description
An authoritative investigation of the sources andtreatment of osteoarthritic joint pain Millions of people throughout the world suffer from osteoarthritis (OA)—a medical condition causing its sufferers excruciating pain that is often disabling. This is the first book to offer clinicians an in-depth understanding of the biological sources of osteoarthritic pain and how they can be treated. Here, a team of leading international authorities has contributed state-of-the-art information on: The Neuroscience of Articular Pain—spinal and peripheral mechanisms of joint pain; experimental models for the study of osteoarthritic pain; inflammatory mediators and nociception in arthritis; phantoms in rheumatology; and more Osteoarthritis and Pain—joint mechanisms and neuromuscular aspects of OA; bone pain and pressure in OA joints; structural correlates of OA pain; and more Treatment of Osteoarthritic Pain—general approaches to treatment; treatments targeting pain receptors; treatments targeting biomechanical abnormalities; and treatments targeting inflammation Whether you're a medical professional, researcher, student, or a generalist or specialist focusing on pain or arthritis, this is your one-stop reference for understanding and treating joint pain in osteoarthritis.
Publisher: John Wiley & Sons
ISBN: 9780470930557
Category : Medical
Languages : en
Pages : 320
Book Description
An authoritative investigation of the sources andtreatment of osteoarthritic joint pain Millions of people throughout the world suffer from osteoarthritis (OA)—a medical condition causing its sufferers excruciating pain that is often disabling. This is the first book to offer clinicians an in-depth understanding of the biological sources of osteoarthritic pain and how they can be treated. Here, a team of leading international authorities has contributed state-of-the-art information on: The Neuroscience of Articular Pain—spinal and peripheral mechanisms of joint pain; experimental models for the study of osteoarthritic pain; inflammatory mediators and nociception in arthritis; phantoms in rheumatology; and more Osteoarthritis and Pain—joint mechanisms and neuromuscular aspects of OA; bone pain and pressure in OA joints; structural correlates of OA pain; and more Treatment of Osteoarthritic Pain—general approaches to treatment; treatments targeting pain receptors; treatments targeting biomechanical abnormalities; and treatments targeting inflammation Whether you're a medical professional, researcher, student, or a generalist or specialist focusing on pain or arthritis, this is your one-stop reference for understanding and treating joint pain in osteoarthritis.
Systems Biology of Free Radicals and Antioxidants
Author: Ismail Laher
Publisher: Springer
ISBN: 9783642300172
Category : Medical
Languages : en
Pages : 0
Book Description
The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.
Publisher: Springer
ISBN: 9783642300172
Category : Medical
Languages : en
Pages : 0
Book Description
The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.
Principles of Bone Biology
Author: John P. Bilezikian
Publisher: Academic Press
ISBN: 0080568750
Category : Medical
Languages : en
Pages : 2074
Book Description
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Publisher: Academic Press
ISBN: 0080568750
Category : Medical
Languages : en
Pages : 2074
Book Description
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Oxidative Metabolism in Inflammation
Author: Pedro Gonzalez-Menendez
Publisher: Frontiers Media SA
ISBN: 2832556256
Category : Medical
Languages : en
Pages : 170
Book Description
Mitochondrial activity is involved in different functions such as cell proliferation, metabolism, Adenosine triphosphate (ATP) generation, and cell death. Particularly, mitochondria play a major role in inflammatory signaling. They regulate the activation, differentiation, and survival of macrophages, while changes in oxidative metabolism alter polarization. Mitochondria are the main source of free radicals, and macrophages increase their oxidative stress levels when they are active. The enhancement of free radicals generation in the mitochondria can damage healthy cells, leading to inflammation. Thus, several diseases associated with an increase in mitochondrial oxidative stress can be associated with chronic inflammation. The intricate crosstalk of mitochondrial metabolism and the innate immune response is well-known. However, the therapeutical implication of metabolic reprogramming, modifying the metabolic niche, or targeting mitochondria in macrophages in specific inflammatory diseases is still unclear. Thus, the goal of this topic is to understand whether alterations of oxidative metabolism, the release of mitochondrial reactive oxygen species, mitochondrial membrane potential, as well as changes in mitochondrial metabolites regulate innate immunity. On one side, we aim to better understand the mitochondria-dependent regulation of the biology of macrophages. On the other hand, we focus on the study of oxidative metabolism in the inflammatory response associated with chronic diseases, but also under the presence of invading germs. The most recent advances in the topic will help to find new clinical interventions to treat acute and chronic inflammation.
Publisher: Frontiers Media SA
ISBN: 2832556256
Category : Medical
Languages : en
Pages : 170
Book Description
Mitochondrial activity is involved in different functions such as cell proliferation, metabolism, Adenosine triphosphate (ATP) generation, and cell death. Particularly, mitochondria play a major role in inflammatory signaling. They regulate the activation, differentiation, and survival of macrophages, while changes in oxidative metabolism alter polarization. Mitochondria are the main source of free radicals, and macrophages increase their oxidative stress levels when they are active. The enhancement of free radicals generation in the mitochondria can damage healthy cells, leading to inflammation. Thus, several diseases associated with an increase in mitochondrial oxidative stress can be associated with chronic inflammation. The intricate crosstalk of mitochondrial metabolism and the innate immune response is well-known. However, the therapeutical implication of metabolic reprogramming, modifying the metabolic niche, or targeting mitochondria in macrophages in specific inflammatory diseases is still unclear. Thus, the goal of this topic is to understand whether alterations of oxidative metabolism, the release of mitochondrial reactive oxygen species, mitochondrial membrane potential, as well as changes in mitochondrial metabolites regulate innate immunity. On one side, we aim to better understand the mitochondria-dependent regulation of the biology of macrophages. On the other hand, we focus on the study of oxidative metabolism in the inflammatory response associated with chronic diseases, but also under the presence of invading germs. The most recent advances in the topic will help to find new clinical interventions to treat acute and chronic inflammation.
The Growth Plate
Author: Irving M. Shapiro
Publisher: IOS Press
ISBN: 9781586032401
Category : Computers
Languages : en
Pages : 312
Book Description
Evidence generated by a number of genetic studies indicates that growth is regulated by a number of genes and that interference with their expression can have catastrophic effects on the well being of the whole organism. This work covers skeletal development and growth.
Publisher: IOS Press
ISBN: 9781586032401
Category : Computers
Languages : en
Pages : 312
Book Description
Evidence generated by a number of genetic studies indicates that growth is regulated by a number of genes and that interference with their expression can have catastrophic effects on the well being of the whole organism. This work covers skeletal development and growth.