Biosensors Based on Aptamers and Enzymes

Biosensors Based on Aptamers and Enzymes PDF Author: Man Bock Gu
Publisher: Springer
ISBN: 3642541437
Category : Technology & Engineering
Languages : en
Pages : 338

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Book Description
Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Biosensors Based on Aptamers and Enzymes

Biosensors Based on Aptamers and Enzymes PDF Author: Man Bock Gu
Publisher: Springer
ISBN: 3642541437
Category : Technology & Engineering
Languages : en
Pages : 338

Get Book Here

Book Description
Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Biosensors: Essentials

Biosensors: Essentials PDF Author: Gennady Evtugyn
Publisher: Springer Science & Business Media
ISBN: 3642402410
Category : Science
Languages : en
Pages : 274

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Book Description
Today, biosensors are broadly applied in research, clinical diagnosis and monitoring, as well as in pharmaceutical, environmental or food analysis. In this work, the author presents the essentials that advanced students and researchers need to know in order to make full use of this technology. This includes a description of biochemical recognition elements, such as enzymes, antibodies, aptamers or even whole cells. Various signal transducers such as electrochemical and optical transducers, luminescence devices and advanced techniques such as quartz crystal microbalances and MEMS systems are covered as well. Current applications are introduced through various case studies, rounded out by a forward-looking chapter on the prospects for biosensor development offered by nanotechnology, lab-on-a-chip, and biomimetic systems.

Electrochemical Biosensors

Electrochemical Biosensors PDF Author: Ali A. Ensafi
Publisher: Elsevier
ISBN: 0128164921
Category : Science
Languages : en
Pages : 390

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Book Description
Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. - Describes several electrochemical methods used as detection techniques with biosensors - Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor - Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more

The Aptamer Handbook

The Aptamer Handbook PDF Author: Sven Klussmann
Publisher: John Wiley & Sons
ISBN: 3527607919
Category : Science
Languages : en
Pages : 518

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Book Description
In The Aptamer Handbook, leading scientists from academia as well as biotech and pharma companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides with novel functions by in vitro selection. These functions comprise high affinity binding (aptamers), catalytic activity (ribozymes and deoxyribozymes) or combinations of binding and catalytic properties (aptazymes). Basic concepts and technologies describing in detail how these functional oligonucleotides can be identified are presented. Numerous examples demonstrate the versatility of in vitro selected oligonucleotides. Special emphasis has been put on a section that shows the broad applicability of aptamers, e. g. in target validation, for analytics, or as new therapeutics. This first overview in the field is of prime interest for a broad audience of scientists both in academia and in industry who wish to expand their knowledge on the potential of new oligonucleotide functions and their applications.

Biosensors Based on Sandwich Assays

Biosensors Based on Sandwich Assays PDF Author: Fan Xia
Publisher: Springer
ISBN: 9811078351
Category : Science
Languages : en
Pages : 220

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Book Description
This book shows the various sandwich assays that are constructed from recognition molecules, such as antibodies, oligonucleotide sequences and aptamers, developed as a result of nano- and biotechnology advances. It consists of ten chapters presenting interesting examples of these assays, organized according to the type of analytic methods (colorimetric, fluorescence, electrochemical, etc.) and detected objects (protein, nucleic acid, small-molecule, ion, etc.). It also includes a chapter discussing the introduction of sandwich assays as biosensors for the detection of a range of targets. It is an interesting and useful resource for a wide readership in various fields of chemical science and nanotechnology.

Enzymes As Sensors

Enzymes As Sensors PDF Author: Carol A. Fierke
Publisher: Academic Press
ISBN: 9780128054062
Category : Medical
Languages : en
Pages : 514

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Book Description
Volume 589, the latest volume in the Methods in Enzymology series, focuses on enzymes as sensors. Contain contributions from leading authorities Informs and updates on all the latest developments in the field

Trends in Biosensing Research

Trends in Biosensing Research PDF Author: Fred Lisdat
Publisher: Springer Nature
ISBN: 303156913X
Category :
Languages : en
Pages : 448

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Book Description


Development of Biosensors Based on DNA Aptamers for Direct Mycotoxins Detection

Development of Biosensors Based on DNA Aptamers for Direct Mycotoxins Detection PDF Author: Nawel Mejri
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
This aim of this work is to develop ultrasensitive electrochemical biosensors with high affinity toward ochratoxine (OTA) and aflatoxine M1 (AFM1). In order to obtain the best analytical performances, we associated nano-materials in the transducer construction: conducting polypyrrole polymer and poly(amido-amine) dendrimères. Thanks to this association, we benefited from the conducting material's electrical properties, and the large active detection surface dendrimers. For the bimolecular sensing part, we used specific DNA aptamers which allowed us to quantify mycotoxines at nM concentrations. In addition, the different aptamer based biosensors present a very large dynamic ranges. We also demonstrated through the use of different sizes of dendrimers, that the sensitivity depend not only in the affinity between bioreceptors and their target molecules, but also in the physico-chemical properties of the biosensor.

Biosensors in Precision Medicine

Biosensors in Precision Medicine PDF Author: Laís Canniatti Brazaca
Publisher: Elsevier
ISBN: 0443153817
Category : Science
Languages : en
Pages : 409

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Book Description
Biosensors in Precision Medicine: From Fundamentals to Future Trends covers important topics regarding biomarkers, including biomarker discovery, validation, application in precision medicine, the principles of biosensors, their use in precision medicine, important analytical parameters, recent advances in bioreceptors and transduction, and more. Finally, the hottest trends of biosensors in precision medicine, including lab-on-a-chip and wearable devices, advances towards telemedicine, machine learning, artificial intelligence and the commerciality of these devices are discussed. Provides a timely review of the state-of-the-art developments in biosensors and their applications in precision medicine Presents an evaluation of case studies, along with real-life examples Addresses recent trends on biosensors for precision medicine

Biosensors

Biosensors PDF Author: Pier Andrea Serra
Publisher: BoD – Books on Demand
ISBN: 9537619990
Category : Medical
Languages : en
Pages : 314

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Book Description
A biosensor is defined as a detecting device that combines a transducer with a biologically sensitive and selective component. When a specific target molecule interacts with the biological component, a signal is produced, at transducer level, proportional to the concentration of the substance. Therefore biosensors can measure compounds present in the environment, chemical processes, food and human body at low cost if compared with traditional analytical techniques. Bringing together researchers from 11 different countries, this book covers a wide range of aspects and issues related to biosensor technology, such as biosensor applications in the fields of drug discovery, diagnostics and bacteria detection, optical biosensors, biotelemetry and algorithms applied to biosensing.