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Author: Alexander Vologodskii
Publisher: Cambridge University Press
ISBN: 1107034930
Category : Science
Languages : en
Pages : 279
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Book Description
This book surveys the last sixty years of research in the rapidly advancing field of DNA biophysics, addressing key questions and facilitating further research.
Author: Alexander Vologodskii
Publisher: Cambridge University Press
ISBN: 1107034930
Category : Science
Languages : en
Pages : 279
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Book Description
This book surveys the last sixty years of research in the rapidly advancing field of DNA biophysics, addressing key questions and facilitating further research.
Author: Mark C. Williams
Publisher: Springer
ISBN: 9781461426950
Category : Science
Languages : en
Pages : 350
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Book Description
Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear. However, the promise of single molecule biophysics is to contribute to the understanding of specific fields of biology using new methods. This book would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists. The subject of the book will be the biophysics of DNA-protein interactions, and will include new methods and results that describe the physical mechanism by which proteins interact with DNA. For example, there has been much recent work on the mechanism by which proteins search for specific binding sites on DNA. A few chapters will be devoted to experiments and theory that shed light on this important problem. We will also cover proteins that alter DNA properties to facilitate interactions important for transcription or replication. Another section of the book will cover the biophysical mechanism by which motor proteins interact with DNA. Finally, we will cover larger protein-DNA complexes, such as replication forks, recombination complexes, DNA repair interactions, and their chromatin context.
Author: Stefan University Press, The
Publisher:
ISBN: 9781889545226
Category :
Languages : en
Pages :
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Book Description
Author: Mark C. Williams
Publisher: Springer Science & Business Media
ISBN: 0387928081
Category : Science
Languages : en
Pages : 354
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Book Description
Depite the rapid expansion of the field of biophysics, there are very few books that comprehensively treat specific topics in this area. Recently, the field of single molecule biophysics has developed very quickly, and a few books specifically treating single molecule methods are beginning to appear. However, the promise of single molecule biophysics is to contribute to the understanding of specific fields of biology using new methods. This book would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists. The subject of the book will be the biophysics of DNA-protein interactions, and will include new methods and results that describe the physical mechanism by which proteins interact with DNA. For example, there has been much recent work on the mechanism by which proteins search for specific binding sites on DNA. A few chapters will be devoted to experiments and theory that shed light on this important problem. We will also cover proteins that alter DNA properties to facilitate interactions important for transcription or replication. Another section of the book will cover the biophysical mechanism by which motor proteins interact with DNA. Finally, we will cover larger protein-DNA complexes, such as replication forks, recombination complexes, DNA repair interactions, and their chromatin context.
Author: Thomas Andrew Waigh
Publisher: John Wiley & Sons
ISBN: 0470513160
Category : Science
Languages : en
Pages : 436
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Book Description
This book presents the fundamentals of molecular biophysics, and highlights the connection between molecules and biological phenomena, making it an important text across a variety of science disciplines. The topics covered in the book include: Phase transitions that occur in biosystems (protein crystallisation, globule-coil transition etc) Liquid crystallinity as an example of the delicate range of partially ordered phases found with biological molecules How molecules move and propel themselves at the cellular level The general features of self-assembly with examples from proteins The phase behaviour of DNA The physical toolbox presented within this text will form a basis for students to enter into a wide range of pure and applied bioengineering fields in medical, food and pharmaceutical areas.
Author: William Bialek
Publisher: Princeton University Press
ISBN: 1400845572
Category : Science
Languages : en
Pages : 653
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Book Description
A physicist's guide to the phenomena of life Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology—from the discovery of DNA's structure to imaging of the human brain—have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles—the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes
Author: A. L. Stanford
Publisher: Academic Press
ISBN: 1483276449
Category : Science
Languages : en
Pages : 407
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Book Description
Foundations of Biophysics serves as an introductory textbook for physical science students to the principles and problems of the life sciences. The book offers to teach physical science students the basic vocabulary of the life sciences and the applications of physics and chemistry to a wide range of biological problems. Topics presented in the book include biological vocabulary and concepts; biological functions at the molecular level of each biological system; and commonly used tools of experimental biophysics. Students in the field of physics, chemistry, biology, and engineering will find the book a good learning material.
Author: Ludmila V. Yakushevich
Publisher: John Wiley & Sons
ISBN: 9780471978244
Category : Science
Languages : en
Pages : 230
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Book Description
Nichtlineare Effekte sind für das Verhalten von DNA-Molekülen von entscheidender Bedeutung und erst ihre Berücksichtigung ermöglicht eine sinnvolle Auswertung von experimentellen Daten.
Author: Jack A. Tuszynski
Publisher: CRC Press
ISBN: 0203009967
Category : Science
Languages : en
Pages : 579
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Book Description
Molecular biophysics is a rapidly growing field of research that plays an important role in elucidating the mysteries of life's molecules and their assemblies, as well as the relationship between their structure and function. Introduction to Molecular Biophysics fills an existing gap in the literature on this subject by providing the reader with th
Author: Ludmila V. Yakushevich
Publisher: Wiley-VCH
ISBN: 9783527404179
Category : Science
Languages : en
Pages : 205
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Book Description
The first edition of this book was the first on the physics of DNA to go beyond the simple (simplified) 'linear' approach, and it has since been found that the inclusion of nonlinear effects leads to a significantly improved interpretation of experimental data. This new edition naturally retains this approach, but has been completely revised, updated and expanded to cover recent developments. Beginning with introductory chapters on DNA structure and dynamics, the book also includes a comparison between linear and nonlinear approaches to the DNA molecule, a chapter devoted to the statistics of nonlinear excitations of DNA, and examples for the interpretation of experimental data on the dynamics of DNA in terms of nonlinear theory. Essential reading for researchers in biophysics and nonlinear physics, allowing biologists, chemists and physicists to continue developing new and improved techniques of investigating the DNA molecule.
