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Author: Zhaomin Yang
Publisher: Caister Academic Press Limited
ISBN: 9781908230348
Category : Medical
Languages : en
Pages : 0
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Book Description
Myxobacteria have fascinated generations of scientists since discovery over a century ago. These bacteria represent the epitome of complex prokaryotic behavior. Their predatory swarms move over solid surfaces, utilizing two distinct motility machineries: one driven by retractable pili and the other by a novel gliding machinery. Furthermore, under nutrient limitation, myxobacteria enter a developmental program featuring distinct cell fates and culminating in the formation of multicellular fruiting bodies filled with dormant spores. In this book, expert myxobiologists describe important recent advances in understanding the behavior of these bacteria at a molecular and cellular level. The book covers ecology, genomics, and cell biology, as well as modeling and simulation on topics including motility, development, and their associated genetic regulatory networks. It provides the most up-to-date overview on myxobacteria and highlights open questions in the active areas of research. Serving as an essential reference for everyone working with myxobacteria, the book's chapters have been written and structured to be accessible to teachers, graduate students, and advanced undergraduate students new to myxobacteria, as well as to experts in other fields, including physical and computational sciences.
Author: Zhaomin Yang
Publisher: Caister Academic Press Limited
ISBN: 9781908230348
Category : Medical
Languages : en
Pages : 0
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Book Description
Myxobacteria have fascinated generations of scientists since discovery over a century ago. These bacteria represent the epitome of complex prokaryotic behavior. Their predatory swarms move over solid surfaces, utilizing two distinct motility machineries: one driven by retractable pili and the other by a novel gliding machinery. Furthermore, under nutrient limitation, myxobacteria enter a developmental program featuring distinct cell fates and culminating in the formation of multicellular fruiting bodies filled with dormant spores. In this book, expert myxobiologists describe important recent advances in understanding the behavior of these bacteria at a molecular and cellular level. The book covers ecology, genomics, and cell biology, as well as modeling and simulation on topics including motility, development, and their associated genetic regulatory networks. It provides the most up-to-date overview on myxobacteria and highlights open questions in the active areas of research. Serving as an essential reference for everyone working with myxobacteria, the book's chapters have been written and structured to be accessible to teachers, graduate students, and advanced undergraduate students new to myxobacteria, as well as to experts in other fields, including physical and computational sciences.
Author: Christoph Wittmann
Publisher: John Wiley & Sons
ISBN: 352734179X
Category : Science
Languages : en
Pages : 789
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Book Description
The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses.
Author: David E. Whitworth
Publisher:
ISBN: 9781555814205
Category : Science
Languages : en
Pages : 0
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Book Description
This volume represents a major review of many aspects of myxobacterial biology, including multicellularity, social behavior, differentiation, cellular regulation, metabolism, evolution, and ecology. Synthesizing the latest knowledge on myxobacteria, this accessible volume will be indispensable for both specialists and nonspecialists interested in the field.
Author: Stanley Falkow
Publisher: Springer Science & Business Media
ISBN: 0387254978
Category : Science
Languages : en
Pages : 1105
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Book Description
The revised Third Edition of The Prokaryotes, acclaimed as a classic reference in the field, offers new and updated articles by experts from around the world on taxa of relevance to medicine, ecology and industry. Entries combine phylogenetic and systematic data with insights into genetics, physiology and application. Existing entries have been revised to incorporate rapid progress and technological innovation. The new edition improves on the lucid presentation, logical layout and abundance of illustrations that readers rely on, adding color illustration throughout. Expanded to seven volumes in its print form, the new edition adds a new, searchable online version.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309264324
Category : Medical
Languages : en
Pages : 633
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Book Description
Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.
Author: Nicholas P. Money
Publisher: OUP Oxford
ISBN: 0191503924
Category : Science
Languages : en
Pages : 137
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Book Description
In recent decades we have come to realize that the microbial world is hugely diverse, and can be found in the most extreme environments. Fungi, single-celled protists, bacteria, archaea, and the vast array of viruses and sub-viral particles far outnumber plants and animals. Microbes, we now know, play a critical role in ecosystems, in the chemistry of atmosphere and oceans, and within our bodies. The field of microbiology, armed with new techniques from molecular biology, is now one of the most vibrant in the life sciences. In this Very Short Introduction Nicholas P. Money explores not only the traditional methods of microscopy and laboratory culture but also the modern techniques of genetic detection and DNA sequencing, genomic analysis, and genetic manipulation. In turn he demonstrates how advances in microbiology have had a tremendous impact on the areas of medicine, agriculture, and biotechnology. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Author: Joachim Wink
Publisher: Springer
ISBN: 3319603396
Category : Science
Languages : en
Pages : 398
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Book Description
This book provides in-depth insights into the biology, taxonomy, genetics, physiology and biotechnological applications of Actinobacteria. It especially focuses on the latter, reviewing the wide variety of actinobacterial bioactive molecules and their benefits for diverse industrial applications such as agriculture, aquaculture, biofuel production and food technology. Actinobacteria are one of the most promising sources of small bioactive molecules and it is estimated that only a small percentage of actinobacterial bioactive chemicals have been discovered to date. Identifying new diverse gene clusters of biotechnological relevance in the genome of Actinobacteria will be crucial to developing advanced applications for pharmaceutical, industrial and agricultural purposes. The book offers a unique resource for all graduate students, researchers and practitioners in the fields of microbiology, microbial biotechnology, and the genetic engineering of Actinobacteria.
Author: Honghui Zhu
Publisher: Frontiers Media SA
ISBN: 2832551777
Category : Science
Languages : en
Pages : 190
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Book Description
Myxobacteria are ubiquitous Gram-negative soil bacteria with a complex multicellular population behavior. They are highly social microbes that move, hunt and develop to build fruiting bodies, which are associated with feeding on a diverse range of bacteria and fungi for nutrition. Therefore, myxobacteria are classified as keystone taxa in the microbial food web and are key players in determining community organization, with potential applications in the biocontrol of plant diseases, wastewater treatment, and bioconversion. In addition, myxobacteria are regarded as natural pharmaceutical and functional enzyme factories due to their diversity and the unique properties of their secondary metabolites and enzymes, making them highly attractive for resource discovery. However, the difficulty in purifying and cultivating many types of myxobacteria limits the in-depth study of myxobacteria. Otherwise, key factors involved in the biological interaction and bioconversion of myxobacteria taxa remain largely unexplored, hindering their practical applications.
Author: S. Grabley
Publisher: Springer Science & Business Media
ISBN: 9783540648444
Category : Medical
Languages : en
Pages : 380
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Book Description
This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.
Author: Joginder Singh
Publisher: Springer
ISBN: 9811300534
Category : Science
Languages : en
Pages : 396
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Book Description
This book presents a comprehensive overview of the use of microorganisms and microbial metabolites as a future sustainable basis of agricultural, environmental and industrial developments. It provides a holistic approach to the latest advances in the utilization of various microorganism bioprospecting including their wide range of applications, traditional uses, modern practices, and designing strategies to harness their potential. In addition, it highlights advanced microbial bioremediation approaches, including genetic manipulation, metagenomics analysis and bacteriophage-based sensors for the detection of food-borne pathogens. Lastly, it elaborates on the latest advances regarding the role of microbes in the sustainable development of various industrial products.
