Author: M. García-Sancho
Publisher: Springer
ISBN: 0230370934
Category : Science
Languages : en
Pages : 253
Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Biology, Computing, and the History of Molecular Sequencing
Author: M. García-Sancho
Publisher: Springer
ISBN: 0230370934
Category : Science
Languages : en
Pages : 253
Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Publisher: Springer
ISBN: 0230370934
Category : Science
Languages : en
Pages : 253
Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Biology, Computing, and the History of Molecular Sequencing
Author: M. García-Sancho
Publisher: Springer
ISBN: 0230370934
Category : Science
Languages : en
Pages : 419
Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Publisher: Springer
ISBN: 0230370934
Category : Science
Languages : en
Pages : 419
Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Biology, Computing, and the History of Molecular Sequencing
Author: M. García-Sancho
Publisher: Palgrave Macmillan
ISBN: 9780230250321
Category : Science
Languages : en
Pages : 242
Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Publisher: Palgrave Macmillan
ISBN: 9780230250321
Category : Science
Languages : en
Pages : 242
Book Description
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Next-generation DNA Sequencing Informatics
Author: Stuart M. Brown
Publisher:
ISBN: 9781621821236
Category : MEDICAL
Languages : en
Pages : 0
Book Description
"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"
Publisher:
ISBN: 9781621821236
Category : MEDICAL
Languages : en
Pages : 0
Book Description
"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"
A Companion to the History of American Science
Author: Georgina M. Montgomery
Publisher: John Wiley & Sons
ISBN: 1119072220
Category : Science
Languages : en
Pages : 712
Book Description
A Companion to the History of American Science offers a collection of essays that give an authoritative overview of the most recent scholarship on the history of American science. Covers topics including astronomy, agriculture, chemistry, eugenics, Big Science, military technology, and more Features contributions by the most accomplished scholars in the field of science history Covers pivotal events in U.S. history that shaped the development of science and science policy such as WWII, the Cold War, and the Women’s Rights movement
Publisher: John Wiley & Sons
ISBN: 1119072220
Category : Science
Languages : en
Pages : 712
Book Description
A Companion to the History of American Science offers a collection of essays that give an authoritative overview of the most recent scholarship on the history of American science. Covers topics including astronomy, agriculture, chemistry, eugenics, Big Science, military technology, and more Features contributions by the most accomplished scholars in the field of science history Covers pivotal events in U.S. history that shaped the development of science and science policy such as WWII, the Cold War, and the Women’s Rights movement
Data-Centric Biology
Author: Sabina Leonelli
Publisher: University of Chicago Press
ISBN: 022641647X
Category : Philosophy
Languages : en
Pages : 282
Book Description
Over the last two decades, digital access to data has revolutionized research methods and ways of doing science in the biological and biomedical fields. Prominent scientists have characterized this shift as leading to a new, data-intensive paradigm for research, encompassing innovative ways to produce, store, disseminate, and interpret huge masses of data. In this book Sabina Leonelli explores the epistemological challenges this poses to how life is researched and understood. By following how data travels across research contexts, and the role played by standards, theories, models, and human agency in shaping their evidential value, she shows the conditions under which digitally available data further our understanding of life. Turning to how the characteristics of data-intensive science bear on philosophical debates, Leonelli explores the shifting criteria for what counts as scientific evidence and how data are transformed into new knowledge. In short, she argues that a philosophical characterization of how data and knowledge move from one context to another is of fundamental importance to a productive philosophical understanding of contemporary scientific practices."
Publisher: University of Chicago Press
ISBN: 022641647X
Category : Philosophy
Languages : en
Pages : 282
Book Description
Over the last two decades, digital access to data has revolutionized research methods and ways of doing science in the biological and biomedical fields. Prominent scientists have characterized this shift as leading to a new, data-intensive paradigm for research, encompassing innovative ways to produce, store, disseminate, and interpret huge masses of data. In this book Sabina Leonelli explores the epistemological challenges this poses to how life is researched and understood. By following how data travels across research contexts, and the role played by standards, theories, models, and human agency in shaping their evidential value, she shows the conditions under which digitally available data further our understanding of life. Turning to how the characteristics of data-intensive science bear on philosophical debates, Leonelli explores the shifting criteria for what counts as scientific evidence and how data are transformed into new knowledge. In short, she argues that a philosophical characterization of how data and knowledge move from one context to another is of fundamental importance to a productive philosophical understanding of contemporary scientific practices."
DNA Sequencing Protocols
Author: Annette M. Griffin
Publisher: Springer Science & Business Media
ISBN: 1592595103
Category : Science
Languages : en
Pages : 386
Book Description
The purpose of DNA Sequencing Protocols is to provide detailed practical procedures for the widest range of DNA sequencing meth ods, and we believe that all the vanguard techniques now being applied in this fast-evolving field are comprehensively covered. Sequencing technology has advanced at a phenomenal rate since the original methods were first described in the late 1970s and there is now a huge variety of strategies and methods that can be employed to determine the sequence of any DNA of interest. More recently, a large number of new and innovative sequencing techniques have been developed, including the use of such novel polymerases as Tag poly merase and Sequenase, the harnessing of PCR technology for linear amplification (cycle) sequencing, and the advent of automated DNA sequencers. DNA sequencing is surely one of the most important techniques in the molecular biology laboratory. Sequence analysis is providing an increasingly useful approach to the characterization of biological systems, and major multinational projects are already underway to map and sequence the entire genome of organisms, such as Escherichia coli, Saccharomyces cerevisiae, Caenorhabditis elegans, and Homo sapiens. Most scientists recognize the importance of DNA sequence data and perceive DNA sequencing as a valuable and indispensable aspect of their work. Recent technological advances, especially in the area of automated sequencing, have removed much of the drudg ery that was formerly associated with the technique, whereas innova tive computer software has greatly simplified the analysis and manipulation of sequence data.
Publisher: Springer Science & Business Media
ISBN: 1592595103
Category : Science
Languages : en
Pages : 386
Book Description
The purpose of DNA Sequencing Protocols is to provide detailed practical procedures for the widest range of DNA sequencing meth ods, and we believe that all the vanguard techniques now being applied in this fast-evolving field are comprehensively covered. Sequencing technology has advanced at a phenomenal rate since the original methods were first described in the late 1970s and there is now a huge variety of strategies and methods that can be employed to determine the sequence of any DNA of interest. More recently, a large number of new and innovative sequencing techniques have been developed, including the use of such novel polymerases as Tag poly merase and Sequenase, the harnessing of PCR technology for linear amplification (cycle) sequencing, and the advent of automated DNA sequencers. DNA sequencing is surely one of the most important techniques in the molecular biology laboratory. Sequence analysis is providing an increasingly useful approach to the characterization of biological systems, and major multinational projects are already underway to map and sequence the entire genome of organisms, such as Escherichia coli, Saccharomyces cerevisiae, Caenorhabditis elegans, and Homo sapiens. Most scientists recognize the importance of DNA sequence data and perceive DNA sequencing as a valuable and indispensable aspect of their work. Recent technological advances, especially in the area of automated sequencing, have removed much of the drudg ery that was formerly associated with the technique, whereas innova tive computer software has greatly simplified the analysis and manipulation of sequence data.
Regenesis
Author: George M Church
Publisher: Basic Books
ISBN: 0465038654
Category : Science
Languages : en
Pages : 305
Book Description
A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Publisher: Basic Books
ISBN: 0465038654
Category : Science
Languages : en
Pages : 305
Book Description
A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.
Bioinformatics Computing
Author: Bryan P. Bergeron
Publisher: Prentice Hall Professional
ISBN: 9780131008250
Category : Computers
Languages : en
Pages : 472
Book Description
Comprehensive and concise, this handbook has chapters on computing visualization, large database designs, advanced pattern matching and other key bioinformatics techniques. It is a practical guide to computing in the growing field of Bioinformatics--the study of how information is represented and transmitted in biological systems, starting at the molecular level.
Publisher: Prentice Hall Professional
ISBN: 9780131008250
Category : Computers
Languages : en
Pages : 472
Book Description
Comprehensive and concise, this handbook has chapters on computing visualization, large database designs, advanced pattern matching and other key bioinformatics techniques. It is a practical guide to computing in the growing field of Bioinformatics--the study of how information is represented and transmitted in biological systems, starting at the molecular level.
Computing for Comparative Microbial Genomics
Author: David Wayne Ussery
Publisher: Springer Science & Business Media
ISBN: 1848002548
Category : Science
Languages : en
Pages : 272
Book Description
Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.
Publisher: Springer Science & Business Media
ISBN: 1848002548
Category : Science
Languages : en
Pages : 272
Book Description
Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.