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Author: E. E. Bernard
Publisher: Springer Science & Business Media
ISBN: 1468417169
Category : Technology & Engineering
Languages : en
Pages : 407
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Book Description
When the present symposium was first conceived, it was decided that more emphasis be given to contributions from biological laboratories than has typically appeared in previous bionics meetings. Accordingly, most of the invited speakers are biologists, in the broad sense of representing some area of the life sciences. Likewise, many of the submitted papers eventually chosen by the technical com mittee were from the life sCiences, rather than the physical sciences or mathe matics. In this way, it was hoped that a greater direct interest in the technological problems of bionics might be stimulated among biologists, upon whose work much of the success of bionics necessarily lies. Because of the wide interdisciplinary span of the papers, it was necessary to impose some artificial organization upon them, specifically for continuity in the transactions. We elected to put the biological papers first, followed by those which deal with reasonably specific models, and reserveto the last those papers reporting models which are more general in nature. The editorial function was kept to a minimum, with no major alterations of content and few of style being exercised. Several of the papers delivered at the symposium required a longer format for clarity and are included here in ex panded versions. Assitance in the preparation of this volume was received from the National Institute of Neurologic Diseases and Blindness, Grant number B-3896.
Author: E. E. Bernard
Publisher: Springer Science & Business Media
ISBN: 1468417169
Category : Technology & Engineering
Languages : en
Pages : 407
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Book Description
When the present symposium was first conceived, it was decided that more emphasis be given to contributions from biological laboratories than has typically appeared in previous bionics meetings. Accordingly, most of the invited speakers are biologists, in the broad sense of representing some area of the life sciences. Likewise, many of the submitted papers eventually chosen by the technical com mittee were from the life sCiences, rather than the physical sciences or mathe matics. In this way, it was hoped that a greater direct interest in the technological problems of bionics might be stimulated among biologists, upon whose work much of the success of bionics necessarily lies. Because of the wide interdisciplinary span of the papers, it was necessary to impose some artificial organization upon them, specifically for continuity in the transactions. We elected to put the biological papers first, followed by those which deal with reasonably specific models, and reserveto the last those papers reporting models which are more general in nature. The editorial function was kept to a minimum, with no major alterations of content and few of style being exercised. Several of the papers delivered at the symposium required a longer format for clarity and are included here in ex panded versions. Assitance in the preparation of this volume was received from the National Institute of Neurologic Diseases and Blindness, Grant number B-3896.
Author: Eugene E. Bernard
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Eugene E. Bernard
Publisher:
ISBN:
Category : Cybernetics
Languages : en
Pages : 420
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Book Description
Author: Eugene E. Bernard
Publisher:
ISBN:
Category : Biological control systems
Languages : en
Pages : 397
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Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309465184
Category : Technology & Engineering
Languages : en
Pages : 189
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Book Description
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
Author: Eugene E. Bernard
Publisher:
ISBN:
Category : Biological control systems
Languages : en
Pages :
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Book Description
Author: Pablo Carbonell
Publisher: Frontiers Media SA
ISBN: 2889196852
Category : Biotechnology
Languages : en
Pages : 125
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Book Description
One of the key features of biological systems is complexity, where the behavior of high level structures is more than the sum of the direct interactions between single components. Synthetic Biologists aim to use rational design to build new systems that do not already exist in nature and that exhibit useful biological functions with different levels of complexity. One such case is metabolic engineering, where, with the advent of genetic and protein engineering, by supplying cells with chemically synthesized non-natural amino acids and sugars as new building blocks, it is now becoming feasible to introduce novel physical and chemical functions and properties into biological entities. The rules of how complex behaviors arise, however, are not yet well understood. For instance, instead of considering cells as inert chassis in which synthetic devices could be easily operated to impart new functions, the presence of these systems may impact cell physiology with reported effects on transcription, translation, metabolic fitness and optimal resource allocation. The result of these changes in the chassis may be failure of the synthetic device, unexpected or reduced device behavior, or perhaps a more permissive environment in which the synthetic device is allowed to function. While new efforts have already been made to increase standardization and characterization of biological components in order to have well known parts as building blocks for the construction of more complex devices, also new strategies are emerging to better understand the biological dynamics underlying the phenomena we observe. For example, it has been shown that the features of single biological components [i.e. promoter strength, ribosome binding affinity, etc] change depending on the context where the sequences are allocated. Thus, new technical approaches have been adopted to preserve single components activity, as genomic insulation or the utilization of prediction algorithms able to take biological context into account. There have been noteworthy advances for synthetic biology in clinical technologies, biofuel production, and pharmaceuticals production; also, metabolic engineering combined with microbial selection/adaptation and fermentation processes allowed to make remarkable progress towards bio-products formation such as bioethanol, succinate, malate and, more interestingly, heterologous products or even non-natural metabolites. However, despite the many progresses, it is still clear that ad hoc trial and error predominates over purely bottom-up, rational design approaches in the synthetic biology community. In this scenario, modelling approaches are often used as a descriptive tool rather than for the prediction of complex behaviors. The initial confidence on a pure reductionist approach to the biological world has left space to a new and deeper investigation of the complexity of biological processes to gain new insights and broaden the categories of synthetic biology. In this Research Topic we host contributions that explore and address two areas of Synthetic Biology at the intersection between rational design and natural complexity: (1) the impact of synthetic devices on the host cell, or "chassis" and (2) the impact of context on the synthetic devices. Particular attention will be given to the application of these principles to the rewiring of cell metabolism in a bottom-up fashion to produce non-natural metabolites or chemicals that should eventually serve as a substitute for petrol-derived chemicals, and, on a long-term view, to provide economical, ecological and ethical solutions to today’s energetic and societal challenges.
Author: Library of Congress. Copyright Office
Publisher: Copyright Office, Library of Congress
ISBN:
Category : Copyright
Languages : en
Pages : 1116
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Book Description
Includes Part 1, Number 2: Books and Pamphlets, Including Serials and Contributions to Periodicals July - December)
Author:
Publisher: Academic Press
ISBN: 0080566375
Category : Computers
Languages : en
Pages : 415
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Book Description
The survey articles included in Volume 5 have been selected with two aims in mind: to arrive at a balanced sampling of the computer field, and to emphasize the subjects of most active current interest. Articles cover topics such as the role of computers in delivering election results; the state of computer development in the Soviet Union and its neighbors; artificial intelligence; and applications of computers to the design of optical instruments, to nuclear reactor design, and to the determination of the structure of crystals or molecules from X-ray diffraction patterns.
Author: Cornelis Jakob Van Der Klaauw
Publisher: BRILL
ISBN: 9004630856
Category : Science
Languages : en
Pages : 375
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Book Description
