Biological Physics of the Developing Embryo

Biological Physics of the Developing Embryo PDF Author: Gabor Forgacs
Publisher: Cambridge University Press
ISBN: 9781139447317
Category : Science
Languages : en
Pages : 354

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Book Description
During development cells and tissues undergo changes in pattern and form that employ a wider range of physical mechanisms than at any other time in an organism's life. This book shows how physics can be used to analyze these biological phenomena. Written to be accessible to both biologists and physicists, major stages and components of the biological development process are introduced and then analyzed from the viewpoint of physics. The presentation of physical models requires no mathematics beyond basic calculus. Physical concepts introduced include diffusion, viscosity and elasticity, adhesion, dynamical systems, electrical potential, percolation, fractals, reaction-diffusion systems, and cellular automata. With full-color figures throughout, this comprehensive textbook teaches biophysics by application to developmental biology and is suitable for graduate and upper-undergraduate courses in physics and biology.

Biological Physics of the Developing Embryo

Biological Physics of the Developing Embryo PDF Author: Gabor Forgacs
Publisher: Cambridge University Press
ISBN: 9781139447317
Category : Science
Languages : en
Pages : 354

Get Book

Book Description
During development cells and tissues undergo changes in pattern and form that employ a wider range of physical mechanisms than at any other time in an organism's life. This book shows how physics can be used to analyze these biological phenomena. Written to be accessible to both biologists and physicists, major stages and components of the biological development process are introduced and then analyzed from the viewpoint of physics. The presentation of physical models requires no mathematics beyond basic calculus. Physical concepts introduced include diffusion, viscosity and elasticity, adhesion, dynamical systems, electrical potential, percolation, fractals, reaction-diffusion systems, and cellular automata. With full-color figures throughout, this comprehensive textbook teaches biophysics by application to developmental biology and is suitable for graduate and upper-undergraduate courses in physics and biology.

Biological Physics of the Developing Embryo

Biological Physics of the Developing Embryo PDF Author: G. Forgács
Publisher:
ISBN: 9780511201097
Category : Biophysics
Languages : en
Pages : 337

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Book Description
This book shows how physics can be used to analyze the changes that cells and tissues undergo during development. Major stages and components of the biological development process are introduced and analyzed. Full-color throughout, this comprehensive textbook is suitable for graduate and upper-undergraduate courses in physics and biology.

Embryogenesis Explained

Embryogenesis Explained PDF Author: Natalie K Gordon retired
Publisher: World Scientific
ISBN: 9814740691
Category : Science
Languages : en
Pages : 784

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Book Description
The greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory of how embryos build themselves, and combines simple physics with the most recent biochemical and genetic breakthroughs, based on the authors' prediction and then discovery of differentiation waves. They explain their ideas in a form accessible to the lay person and a broad spectrum of scientists and engineers. The diverse subjects of development, genetics and evolution, and their physics, are brought together to explain this major, previously unanswered scientific question of our time. As a follow up on The Hierarchical Genome, this book is a shorter but conceptually expanded work for the reader who is interested in science. It is useful as a starting point for the curious layman or the scientist or professional encountering the problem of embryogenesis without the formal biology background. There is also material useful for the seasoned biologist caught up in the new rush of information about the role of mechanics in developmental biology and cellular level mechanics in medicine.

From Egg to Embryo

From Egg to Embryo PDF Author: J. M. W. Slack
Publisher: CUP Archive
ISBN: 9780521273299
Category : Science
Languages : en
Pages : 260

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Book Description
This book is about the development of the animal embryo starting from the fertilised egg. The emphasis is on the problem of pattern formation: how cells in different regions of the embryo become programmed to form the various structures of the body in the correct relative positions.

A Conceptual History of Modern Embryology

A Conceptual History of Modern Embryology PDF Author: Scott F. Gilbert
Publisher: Springer Science & Business Media
ISBN: 1461568234
Category : Science
Languages : en
Pages : 273

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Book Description
"Glory to the science of embryology!" So Johannes Holtfreter closed his letter to this editor when he granted permission to publish his article in this volume. And glory there is: glory in the phenomenon of animals developing their complex morphologies from fertilized eggs, and glory in the efforts of a relatively small group of scientists to understand these wonderful events. Embryology is unique among the biological disciplines, for it denies the hegemony of the adult and sees value (indeed, more value) in the stages that lead up to the fully developed organism. It seeks the origin, and not merely the maintenance, of the body. And if embryology is the study of the embryo as seen over time, the history of embryology is a second-order derivative, seeing how the study of embryos changes over time. As Jane Oppenheimer pointed out, "Sci ence, like life itself, indeed like history, itself, is a historical phenomenon. It can build itself only out of its past. " Thus, there are several ways in which embryology and the history of embryology are similar. Each takes a current stage of a developing entity and seeks to explain the paths that brought it to its present condition. Indeed, embryology used to be called Entwicklungsgeschichte, the developmental history of the organism. Both embryology and its history interpret the interplay between internal factors and external agents in the causation of new processes and events.

Embryos Under the Microscope

Embryos Under the Microscope PDF Author: Jane Maienschein
Publisher: Harvard University Press
ISBN: 0674725557
Category : Medical
Languages : en
Pages : 349

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Book Description
Jane Maienschein examines how understanding of embryos evolved from the speculations of natural philosophers to bioengineering, with its life-enhancing therapies. She shows that research on embryos has always seemed promising to some but frightening to others, and makes the case that public understanding must be informed by scientific findings.

Human Embryonic Stem Cells in Development

Human Embryonic Stem Cells in Development PDF Author:
Publisher: Academic Press
ISBN: 0128043342
Category : Science
Languages : en
Pages : 204

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Book Description
Human Embryonic Stem Cells in Development, Volume 129, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as recapitulating pancreas development from human embryonic stem cells in a dish, modeling mammalian gastrulation with embryonic stem cells, and a section on what stem cells tell us about human germ cell biology. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series

Embryos under the Microscope

Embryos under the Microscope PDF Author: Jane Maienschein
Publisher: Harvard University Press
ISBN: 0674369734
Category : Science
Languages : en
Pages : 349

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Book Description
Too tiny to see with the naked eye, the human embryo was just a hypothesis until the microscope made observation of embryonic development possible. This changed forever our view of the minuscule cluster of cells that looms large in questions about the meaning of life. Embryos under the Microscope examines how our scientific understanding of the embryo has evolved from the earliest speculations of natural philosophers to today’s biological engineering, with its many prospects for life-enhancing therapies. Jane Maienschein shows that research on embryos has always revealed possibilities that appear promising to some but deeply frightening to others, and she makes a persuasive case that public understanding must be informed by up-to-date scientific findings. Direct observation of embryos greatly expanded knowledge but also led to disagreements over what investigators were seeing. Biologists confirmed that embryos are living organisms undergoing rapid change and are not in any sense functioning persons. They do not feel pain or have any capacity to think until very late stages of fetal development. New information about DNA led to discoveries about embryonic regulation of genetic inheritance, as well as evolutionary relationships among species. Scientists have learned how to manipulate embryos in the lab, taking them apart, reconstructing them, and even synthesizing—practically from scratch—cells, body parts, and maybe someday entire embryos. Showing how we have learned what we now know about the biology of embryos, Maienschein changes our view of what it means to be alive.

Developmental Biology Protocols

Developmental Biology Protocols PDF Author: Rocky S. Tuan
Publisher: Springer Science & Business Media
ISBN: 1592590659
Category : Science
Languages : en
Pages : 537

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Book Description
Developmental biology is one of the most exciting and fast-growing fields today. In part, this is so because the subject matter deals with the innately fascinating biological events—changes in form, structure, and function of the org- ism. The other reason for much of the excitement in developmental biology is that the field has truly become the unifying melting pot of biology, and provides a framework that integrates anatomy, physiology, genetics, biochemistry, and cellular and mole- lar biology, as well as evolutionary biology. No longer is the study of embryonic development merely “embryology.” In fact, development biology has produced - portant paradigms for both basic and clinical biomedical sciences alike. Although modern developmental biology has its roots in “experimental emb- ology” and the even more classical “chemical embryology,” the recent explosive and remarkable advances in developmental biology are critically linked to the advent of the “cellular and molecular biology revolution.” The impressive arsenal of expe- mental and analytical tools derived from cell and molecular biology, which promise to continue to expand, together with the exponentially developing sophistication in fu- tional imaging and information technologies, guarantee that the study of the devel- ing embryo will contribute one of the most captivating areas of biological research in the next millennium.

Cell Signaling During Mammalian Early Embryo Development

Cell Signaling During Mammalian Early Embryo Development PDF Author: Henry J. Leese
Publisher: Springer
ISBN: 149392480X
Category : Science
Languages : en
Pages : 224

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Book Description
The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.