Author: Hitoshi Shichi
Publisher: Elsevier
ISBN: 0323157416
Category : Nature
Languages : en
Pages : 292
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Book Description
Biochemistry of Vision provides information pertinent to vision biochemistry. This book discusses the biochemical information derived primarily from studies on nonocular tissues and describes the biochemical reactions related to the function of the retina and pigmented epithelium. Organized into 16 chapters, this book begins with an overview of the visual system and the structure of the vertebrate eye. The text then proceeds with a discussion of photoreceptor, which has a highly membranous structure. Other chapters cover a brief discussion of several topics, including biomembranes, photochemistry, spectral properties of retinal isomers, and the photochemical properties of the chromophore of rhodopsin. This book discusses as well the properties and intramembrane disposition of rhodopsin. The final chapter deals with the biochemistry of photoreceptor disorders and summarizes the basic knowledge on neurotransmitters and electrophysiology in the retina. This book is intended for ophthalmologists and medical students who are interested in the molecular aspects of photoreceptor diseases.
Author: David R. Whikehart
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 348
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Book Description
This specialized text presents a review of general biochemistry and an in-depth exploration of biochemistry unique to the eye. As a readable introduction to this challenging topic, it describes the molecular structures and biochemical events that occur in the eye. Specific clinical examples link basic science to clinical practice and provide a concrete basis for understanding complex concepts. This edition includes new, updated information in revised chapters plus two additional chapters on ocular fluids and pathology. General biochemistry is discussed in each chapter, with examples of biochemical pathology and disease processes such as age-related cataract formation and ocular diabetes.
Author: Elaine R. Berman
Publisher: Springer Science & Business Media
ISBN: 147579441X
Category : Science
Languages : en
Pages : 489
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Book Description
My first introduction to the eye came more than three decades ago when my close friend and mentor, the late Professor Isaac C. Michaelson, convinced me that studying the biochemistry of ocular tissues would be a rewarding pursuit. I hastened to explain that I knew nothing about the subject, since relatively few basic biochemical studies on ocular tissues had appeared in the world literature. Professor Michaelson assured me, however, that two books on eye biochemistry had already been written. One of them, a beautiful monograph by Arlington Krause ( 1934) of Johns Hopkins Hospital, is we II worth reading even today for its historical perspective. The other, published 22 years later, was written by Antoinette Pirie and Ruth van Heyningen ( 1956), whose pioneering achievements in eye biochemistry at the Nuffield Laboratory of Ophthalmology in Oxford, England are known throughout the eye research community and beyond. To their credit are classical investigations on retinal, corneal, and lens biochemistry, beginning in the 1940s and continuing for many decades thereafter. Their important book written in 1956 on the Biochemistry of the Eye is a volume that stood out as a landmark in this field for many years. In recent years, however, a spectacular amount of new information has been gener ated in ocular biochemistry. Moreover, there is increasing specialization among investiga tors in either a specific field of biochemistry or a particular ocular tissue.
Author:
Publisher: Wayenborgh Publishing
ISBN: 9062998968
Category : Medical
Languages : en
Pages : 972
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Book Description
Author: F. Crescitelli
Publisher: Springer Science & Business Media
ISBN: 3642664687
Category : Medical
Languages : en
Pages : 816
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Book Description
The vertebrate eye has been, and continues to be, an object of interest and of inquiry for biologists, physicists, chemists, psychologists, and others. Quite apart from its important role in the development of ophthalmology and related medical disciplines, the vertebrate eye is an exemplar of the ingenuity of living systems in adapting to the diverse and changing environments in which vertebrates have evolved. The wonder is not so much that the visual system, like other body systems, has been able to adapt in this way, but rather that these adaptations have taken such a variety of forms. In a previous volume in this series (VII/I) Eakin expressed admiration for the diversity of invertebrate photoreceptors. A comparable situation exists for the vertebrate eye as a whole and one object of this volume is to present to the reader the nature of this diversity. One result of this diversification of ocular structures and properties is that the experimental biologist has available a number of systems for study that are unique or especially favorable for the investigation of particular questions in visual science or neurobiology. This volume includes some examples of progress made by the use of such specially selected vertebrate systems. It is our hope that this comparative approach will continue to reveal new and useful preparations for the examination of important questions.
Author: D.G. Stavenga
Publisher: Elsevier
ISBN: 0080536778
Category : Science
Languages : en
Pages : 597
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Book Description
Molecular mechanisms in visual transduction is presently one of the most intensely studied areas in the field of signal transduction research in biological cells. Because the sense of vision plays a primary role in animal biology, and thus has been subject to long evolutionary development, the molecular and cellular mechanisms underlying vision have a high degree of sensitivity and versatility. The aims of visual transduction research are firstto determine which molecules participate, and then to understand how they act in concert to produce the exquisite electrical responses of the photoreceptor cells.Since the 1940s [1] we have known that rod vision begins with the capture of a quantum of energy, a photon, by a visual pigment molecule, rhodopsin. As the function of photon absorption is to convert the visual pigment molecule into a G-protein activating state, the structural details of the visual pigments must beexplained from the perspective of their role in activating their specific G-proteins. Thus, Chapters 1-3 of this Handbook extensively cover the physico-chemical molecular characteristics of the vertebrate rhodopsins. Following photoconversion and G-protein activation, the phototransduction cascade leads to modifications of the population of closed and open ion channels in the photoreceptor plasma membrane, and thereby to the electrical response. The nature of the channels of vertebrate photoreceptors is examined in Chapter 4, and Chapter 5 integrates the present body of knowledge of the activation steps in the cascade into a quantitative framework. Once the phototransduction cascade is activated, it must be subsequently silenced. The various molecular mechanisms participating in inactivation aretreated in Chapters 1-4 and especially Chapter 5. Molecular biology is now an indispensable tool in signal transduction studies. Numerous vertebrate (Chapter 6) and invertebrate (Chapter 7) visual pigments have been characterized and cloned. The genetics and evolutionary aspects of this great subfamily of G-protein activating receptors are intriguing as they present a natural probe for the intimate relationship between structure and function of the visual pigments. Understanding the spectral characteristics from the molecular composition can be expected to
Author: Edwin W. Abrahamson
Publisher: Hutchinson Ross Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 456
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Book Description
Author: G. Tandler
Publisher: Springer Science & Business Media
ISBN: 9400996314
Category : Science
Languages : en
Pages : 307
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Book Description
Author: Jerome J. Wolken
Publisher: Oxford University Press
ISBN: 0198021704
Category : Science
Languages : en
Pages : 274
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Book Description
The influence of light on the lives of living organisms is all-pervasive, affecting movement, vision, behavior, and physiological activity. This book is a biophysically grounded comparative survey of how animals detect light and perceive their surroundings. Included are discussions of photoreceptors, light emitters, and eyes. The book focuses in particular on the kinds of optical systems that have evolved, beginning with unicellular organisms that detect and respond to light through to more advanced and complex designs for imaging. The relevance of these studies extends beyond biology, since these findings can be used to help develop photoreceptor energy conversion and information systems, and optical imaging devices with a wide range of everyday applications. The book will appeal to biophysicists, photobiologists, bioengineers, neuroscientists, and all researchers working in the area of vision and visual optics.
Author: National Institutes of Health (U.S.). Committee Management Staff
Publisher:
ISBN:
Category : Public health advisory groups
Languages : en
Pages : 776
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Book Description
