Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering

Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering PDF Author: Gang Wu
Publisher: Frontiers Media SA
ISBN: 2832512895
Category : Science
Languages : en
Pages : 348

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Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering

Bioactive Agents for Functionalization of Biomaterials for Precise Tissue Engineering PDF Author: Gang Wu
Publisher: Frontiers Media SA
ISBN: 2832512895
Category : Science
Languages : en
Pages : 348

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Book Description


Advanced Biomaterials and Systems Releasing Bioactive Agents for Precise Tissue Regeneration

Advanced Biomaterials and Systems Releasing Bioactive Agents for Precise Tissue Regeneration PDF Author: Rui Guo
Publisher: Frontiers Media SA
ISBN: 2889715361
Category : Technology & Engineering
Languages : en
Pages : 252

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Functional Biomaterials

Functional Biomaterials PDF Author: Sougata Jana
Publisher: Springer Nature
ISBN: 9811671524
Category : Science
Languages : en
Pages : 524

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Book Description
This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.

Biomaterials in Tissue Engineering and Regenerative Medicine

Biomaterials in Tissue Engineering and Regenerative Medicine PDF Author: Birru Bhaskar
Publisher: Springer Nature
ISBN: 9811600023
Category : Medical
Languages : en
Pages : 587

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Book Description
This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.

Synthesis, Functionalization, and Clinical Translation of Pharmaceutical Biomaterials

Synthesis, Functionalization, and Clinical Translation of Pharmaceutical Biomaterials PDF Author: Jianxun Ding
Publisher: Frontiers Media SA
ISBN: 2889711935
Category : Science
Languages : en
Pages : 457

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Functional Biomaterials

Functional Biomaterials PDF Author: Anuj Kumar
Publisher: CRC Press
ISBN: 1000912086
Category : Medical
Languages : en
Pages : 325

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Book Description
Discusses design chemistry, modification, and processing of biomaterials Describes the efficacy of biomaterials at various scales for biological response and drug delivery Demonstrates technological advances from conventional to additive manufacturing Covers future of biofabrication and customized medical devices

Biologically-responsive Hybrid Biomaterials

Biologically-responsive Hybrid Biomaterials PDF Author: Esmaiel Jabbari
Publisher: World Scientific
ISBN: 981429568X
Category : Medical
Languages : en
Pages : 430

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Book Description
Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.

Biomaterials and Bioactive Molecules to Drive Differentiation in Striated Muscle Tissue Engineering

Biomaterials and Bioactive Molecules to Drive Differentiation in Striated Muscle Tissue Engineering PDF Author: Valentina Di Felice
Publisher: Frontiers Media SA
ISBN: 2889198413
Category : Physiology
Languages : en
Pages : 92

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Book Description
Tissue engineering is an innovative, multidisciplinary approach which combines (bio)materials, cells and growth factors with the aim to obtain neo-organogenesis to repair or replenish damaged tissues and organs. The generation of engineered tissues and organs (e. g. skin and bladder) has entered into the clinical practice in response to the chronic lack of organ donors. In particular, for the skeletal and cardiac muscles the translational potential of tissue engineering approaches has clearly been shown, even though the construction of this tissue lags behind others given the hierarchical, highly organized architecture of striated muscles. Cardiovascular disease is the leading cause of death in the developed world, where the yearly incidence of Acute MI (AMI) is approx 2 million cases in Europe. Recovery from AMI and reperfusion is still less than ideal. Stem cell therapy may represent a valid treatment. However, delivery of stem cells alone to infarcted myocardium provides no structural support while the myocardium heals, and the injected stem cells do not properly integrate into the myocardium because they are not subjected to the mechanical forces that are known to drive myocardial cellular physiology. On the other hand, there are many clinical cases where the loss of skeletal muscle due to a traumatic injury, an aggressive tumour or prolonged denervation may be cured by the regeneration of this tissue. In vivo, stem or progenitor cells are sheltered in a specialized microenvironment (niche), which regulates their survival, proliferation and differentiation. The goal of this research topic is to highlight the available knowledge on biomaterials and bioactive molecules or a combination of them, which can be used successfully to differentiate stem or progenitor cells into beating cardiomyocytes or organized skeletal muscle in vivo. Innovations compared to the on-going trials may be: 1) the successful delivery of stem cells using sutural scaffolds instead of intracoronary or intramuscular injections; 2) protocols to use a limited number of autologous or allogeneic stem cells; 3) methods to drive their differentiation by modifying the chemical-physical properties of scaffolds or biomaterials, incorporating small molecules (i.e. miRNA) or growth factors; 4) methods to tailor the scaffolds to the elastic properties of the muscle; 5) studies which suggest how to realize scaffolds that optimize tissue functional integration, through the combination of the most up-to-date manufacturing technologies and use of bio-polymers with customized degradation properties.

Biologically Responsive Biomaterials for Tissue Engineering

Biologically Responsive Biomaterials for Tissue Engineering PDF Author: Iulian Vasile Antoniac
Publisher: Springer Science & Business Media
ISBN: 146144327X
Category : Technology & Engineering
Languages : en
Pages : 261

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Book Description
Developments in the area of biomaterials, bionanotechnology, tissue engineering, and medical devices are becoming the core of health care. Almost all medical specialties involve the use of biomaterials, and research plays a key role in the development of new and improved treatment modalities. This volume focuses on several current trends in tissue engineering, remodelling and regeneration. Leading researchers describe the use of nanomaterials to create new functionalities when interfaced with biological molecules or structures. In addition to coverage of basic science and engineering aspects, a range of applications in bionanotechnology are presented, including diagnostic devices, contrast agents, analytical tools, physical therapy applications, and vehicles for targeted drug delivery. The use of polymers, alloys, and composites, or a combination of these, for biomaterials applications in orthopaedics is also explored. These contributions represent essential reading for the biomaterials and biomedical engineering communities, and can serve as instructional course lectures targeted at graduate and post-graduate students.

Handbook of Biomaterials for Medical Applications, Volume 1

Handbook of Biomaterials for Medical Applications, Volume 1 PDF Author: Deepa Suhag
Publisher: Springer Nature
ISBN: 9819748186
Category :
Languages : en
Pages : 391

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Book Description