Alphaherpesviruses

Alphaherpesviruses PDF Author: Sandra Knowles Weller
Publisher: Caister Academic Press Limited
ISBN: 9781904455769
Category : Science
Languages : en
Pages : 0

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Book Description
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.

Alphaherpesviruses

Alphaherpesviruses PDF Author: Sandra Knowles Weller
Publisher: Caister Academic Press Limited
ISBN: 9781904455769
Category : Science
Languages : en
Pages : 0

Get Book Here

Book Description
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.

Fletcherism: What It Is; Or, How I Became Young at Sixty

Fletcherism: What It Is; Or, How I Became Young at Sixty PDF Author: Horace Fletcher
Publisher: DigiCat
ISBN:
Category : Fiction
Languages : en
Pages : 121

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Book Description
"Fletcherism: what it is: or, How I became young at sixty" by Horace fletcher is a fascinating book on nutrition and diet. The author here relates briefly the story of his regeneration, of how he rescued himself from the prospect of an early grave, and brought himself to his present splendid physical and mental condition. He tells of the discovery of his principles, which have helped millions of people to live better, happier, and healthier lives. The book is a good fit if you are concerned about health and diet.

Bacchantes

Bacchantes PDF Author: Euripides
Publisher:
ISBN:
Category : Greek drama (Tragedy)
Languages : en
Pages : 164

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Book Description


Environment, Health, and Safety

Environment, Health, and Safety PDF Author: Lari A. Bishop
Publisher:
ISBN:
Category : Corporations
Languages : en
Pages : 50

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Book Description


Hallelujah Trombone!

Hallelujah Trombone! PDF Author: Paul E. Bierley
Publisher: Grupo Editorial Norma
ISBN: 9780825849664
Category : Composers
Languages : en
Pages : 180

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Book Description


Textual Criticism of the Hebrew Bible

Textual Criticism of the Hebrew Bible PDF Author: Emanuel Tov
Publisher: BRILL
ISBN: 9004502734
Category : Religion
Languages : en
Pages : 496

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Book Description
Customers in North America who wish to purchase this publication, please contact Augsburg Fortress Press. First published in 1992, Emanuel Tov’s Textual Criticism of the Hebrew Bible has rapidly established itself as the authoritative reference work for all those engaged in the study of the text of the Hebrew Bible. This thoroughly revised second edition will be welcomed by students and scholars alike. A wide range of readers will find this book accessible and indispensable. Emanuel Tov offers extensive descriptions of the major witnesses to the text of the Hebrew Bible–the Hebrew texts from Qumran, the Septuagint, the Masoretic Text–as well as the Aramaic Targumim, the Syriac translations, the Vulgate, and others. Special attention is given to the exegetical aspects of the textual transmission, literary issues, and the problem of the original shape of the biblical text. Praise for the First Edition: “Emanuel Tov is preeminent in the world in the field of Septuagint studies. This is a solid and durable work which, given its technical character, is written in a readable way.” Frank Moore Cross, Harvard University “Nowhere else can you find such a thorough presentation of how the Bible was transmitted in Second Temple times ... This excellently written handbook represents a major step forward for biblical studies.” Lawrence Schiffman, New York University “History will surely regard Emanuel Tov’s monumental work as the definitive discussion of textual criticism of this generation. A ‘must-have’ for any serious scholar of the Bible!” Sidnie A. White, University of Nebraska “The basic reference work on the textual criticism of the Hebrew Bible for at least the next decade. This is a magisterial work which is badly needed and masterfully done.” Journal for the Study of Judaism “This book will soon be viewed as a classic of biblical studies.” Ralph W. Klein, Journal of Religion “Replete with examples, tables, plates, lucid definitions and explanations, as well as extensive bibliographies, the volume brings together a wealth of information not previously so accessible and makes the theory and practice of textual criticism easily understandable and visually clear.” Judith E. Sanderson, Seattle University

The Traditional Text of the Holy Gospels Vindicated and Established

The Traditional Text of the Holy Gospels Vindicated and Established PDF Author: John William Burgon
Publisher:
ISBN:
Category : Bible
Languages : en
Pages : 348

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Book Description


On Holy Scripture and Criticism

On Holy Scripture and Criticism PDF Author: Herbert Edward Ryle
Publisher:
ISBN:
Category : Bible
Languages : en
Pages : 248

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Book Description


The Samaritans

The Samaritans PDF Author: Moses Gaster
Publisher:
ISBN:
Category : Samaritans
Languages : en
Pages : 262

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Book Description


Eerdmans Commentary on the Bible: Psalms

Eerdmans Commentary on the Bible: Psalms PDF Author: Willem S. Prinslo
Publisher: Wm. B. Eerdmans Publishing
ISBN: 1467453692
Category : Religion
Languages : en
Pages : 1672

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Book Description
This extract from the Eerdmans Commentary on the Bible provides Prinslo’s introduction to and concise commentary on Psalms. The Eerdmans Commentary on the Bible presents, in nontechnical language, the best of modern scholarship on each book of the Bible, including the Apocrypha. Reader-friendly commentary complements succinct summaries of each section of the text and will be valuable to scholars, students, and general readers. Rather than attempt a verse-by-verse analysis, these volumes work from larger sense units, highlighting the place of each passage within the overarching biblical story. Commentators focus on the genre of each text—parable, prophetic oracle, legal code, and so on—interpreting within the historical and literary context. The volumes also address major issues within each biblical book—including the range of possible interpretations—and refer readers to the best resources for further discussions.