Basic Concepts in Medicinal Chemistry PDF Download
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Author: Marc Harrold
Publisher: ASHP
ISBN: 1585283649
Category : Medical
Languages : en
Pages : 405
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Book Description
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author: Marc Harrold
Publisher: ASHP
ISBN: 1585283649
Category : Medical
Languages : en
Pages : 405
Get Book
Book Description
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author: Chris J. Jones
Publisher: Springer
ISBN:
Category : Education
Languages : en
Pages : 196
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Book Description
The material is aimed at first and second year undergraduates, with a view to providing a basis for more advanced studies.
Author: Leo J. Malone
Publisher: John Wiley & Sons
ISBN: 047174154X
Category : Science
Languages : en
Pages : 1449
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Book Description
Engineers who need to have a better understanding of chemistry will benefit from this accessible book. It places a stronger emphasis on outcomes assessment, which is the driving force for many of the new features. Each section focuses on the development and assessment of one or two specific objectives. Within each section, a specific objective is included, an anticipatory set to orient the reader, content discussion from established authors, and guided practice problems for relevant objectives. These features are followed by a set of independent practice problems. The expanded Making it Real feature showcases topics of current interest relating to the subject at hand such as chemical forensics and more medical related topics. Numerous worked examples in the text now include Analysis and Synthesis sections, which allow engineers to explore concepts in greater depth, and discuss outside relevance.
Author: Chris McMullen
Publisher: Createspace Independent Publishing Platform
ISBN: 9781479134632
Category : Chemistry
Languages : en
Pages : 0
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Book Description
EDITIONS: This book is available in paperback in 5.5" x 8.5" (portable size), 8.5" x 11" (large size), and as an eBook. This 5.5" x 8.5" edition is the most portable, while the details of the figures - including the periodic tables - are most clear in the large size and large print edition. However, the paperback editions are in black-and-white, whereas the eBooks are in color. OVERVIEW: This book focuses on fundamental chemistry concepts, such as understanding the periodic table of the elements and how chemical bonds are formed. No prior knowledge of chemistry is assumed. The mathematical component involves only basic arithmetic. The content is much more conceptual than mathematical. AUDIENCE: It is geared toward helping anyone - student or not - to understand the main ideas of chemistry. Both students and non-students may find it helpful to be able to focus on understanding the main concepts without the constant emphasis on computations that is generally found in chemistry lectures and textbooks. CONTENTS: (1) Understanding the organization of the periodic table, including trends and patterns. (2) Understanding ionic and covalent bonds and how they are formed, including the structure of valence electrons. (3) A set of rules to follow to speak the language of chemistry fluently: How to name compounds when different types of compounds follow different naming schemes. (4) Understanding chemical reactions, including how to balance them and a survey of important reactions. (5) Understanding the three phases of matter: properties of matter, amorphous and crystalline solids, ideal gases, liquids, solutions, and acids/bases. (6) Understanding atomic and nuclear structure and how it relates to chemistry. (7) VErBAl ReAcTiONS: A brief fun diversion from science for the verbal side of the brain, using symbols from chemistry's periodic table to make word puzzles. ANSWERS: Every chapter includes self-check exercises to offer practice and help the reader check his or her understanding. 100% of the exercises have answers at the back of the book. COPYRIGHT: Teachers who purchase one copy of this book or borrow one copy of this book from a library may reproduce selected pages for the purpose of teaching chemistry concepts to their own students.
Author: Robert Boyle
Publisher: BoD – Books on Demand
ISBN: 3752370815
Category : Fiction
Languages : en
Pages : 182
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Book Description
Reproduction of the original: The Sceptical Chymist by Robert Boyle
Author: David A. Ucko
Publisher: Elsevier
ISBN: 1483271102
Category : Science
Languages : en
Pages : 705
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Book Description
Basics of Chemistry provides the tools needed in the study of General Chemistry such as problem solving skills, calculation methods and the language and basic concepts of chemistry. The book is designed to meet the specific needs of underprepared students. Concepts are presented only as they are needed, and developed from the simple to the complex. The text is divided into 18 chapters, each covering some particular aspect of chemistry such as matter, energy, and measurement; the properties of atoms; description of chemical bonding; study of chemical change; and nuclear and organic chemistry. Undergraduate students will find the book as a very valuable academic material.
Author: D. N. Singh
Publisher: Pearson Education India
ISBN: 8131798682
Category : Chemistry, Inorganic
Languages : en
Pages : 557
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Book Description
Basic Concepts of Inorganic Chemistry is thoroughly revised and designed as a student text to meet the needs of the students preparing for various competitive examinations. Each concept and principle is unfolded systematically, reflecting the vast experience, command and authority of the author on the subject. The subject has been explained using basic principles that make things easy to understand and absorb both for beginners as well as advanced learners. Each chapter is followed by graded multiple choice questions (the core of the competitive exams) based on concepts, principles and applications, providing the student with necessary recapitulation and ensuring speed and accuracy.
Author: Leo Michels
Publisher: Cengage Learning
ISBN: 9780534265748
Category : Chemistry
Languages : en
Pages : 0
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Book Description
Emphasizes the mathematical and conceptual skills needed for preparatory and general chemistry
Author: Des W. Connell
Publisher: CRC Press
ISBN: 0203025385
Category : Science
Languages : en
Pages : 480
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Book Description
Basic Concepts of Environmental Chemistry, Second Edition provides a theoretical basis for the behavior and biological effects of natural chemical entities and contaminants in natural systems, concluding with a practical focus on risk assessment and the environmental management of chemicals. The text uses molecular properties such as pola
Author: Jonathan W. Steed
Publisher: John Wiley & Sons
ISBN: 9780470858707
Category : Science
Languages : en
Pages : 320
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Book Description
Supramolecular chemistry and nanochemistry are two strongly interrelated cutting edge frontiers in research in the chemical sciences. The results of recent work in the area are now an increasing part of modern degree courses and hugely important to researchers. Core Concepts in Supramolecular Chemistry and Nanochemistry clearly outlines the fundamentals that underlie supramolecular chemistry and nanochemistry and takes an umbrella view of the whole area. This concise textbook traces the fascinating modern practice of the chemistry of the non-covalent bond from its fundamental origins through to it expression in the emergence of nanochemistry. Fusing synthetic materials and supramolecular chemistry with crystal engineering and the emerging principles of nanotechnology, the book is an ideal introduction to current chemical thought for researchers and a superb resource for students entering these exciting areas for the first time. The book builds from first principles rather than adopting a review style and includes key references to guide the reader through influential work. supplementary website featuring powerpoint slides of the figures in the book further references in each chapter builds from first principles rather than adopting a review style includes chapter on nanochemistry clear diagrams to highlight basic principles
