Aziridines and Epoxides in Organic Synthesis

Aziridines and Epoxides in Organic Synthesis PDF Author: Andrei K. Yudin
Publisher: John Wiley & Sons
ISBN: 9783527312139
Category : Science
Languages : en
Pages : 532

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Book Description
Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons. Besides their importance as reactive intermediates, many biologically active compounds also contain these three-membered rings. Filling a gap in the literature, this clearly structured book presents the much needed information in a compact and concise way. The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth. Divided roughly equally between aziridines and epoxides, the twelve chapters discuss: * Synthesis of aziridines * Nucleophilic ring-opening of aziridines and epoxides * Organic synthesis with aziridine building blocks * Vinyl aziridines in organic synthesis * Diastereoselective aziridination reagents * Synthetic aspects of aziridinomitocene chemistry * Biosynthesis of biologically important aziridines * Organic catalysis of epoxide and aziridine ring formation * Metal-mediated synthesis of epoxides * Asymmetric epoxide ring opening chemistry * Epoxides in complex molecule synthesis * Biological activity of epoxide-containing molecules A high-quality reference manual for academic and industrial chemists alike.

Aziridines and Epoxides in Organic Synthesis

Aziridines and Epoxides in Organic Synthesis PDF Author: Andrei K. Yudin
Publisher: John Wiley & Sons
ISBN: 9783527312139
Category : Science
Languages : en
Pages : 532

Get Book Here

Book Description
Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons. Besides their importance as reactive intermediates, many biologically active compounds also contain these three-membered rings. Filling a gap in the literature, this clearly structured book presents the much needed information in a compact and concise way. The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth. Divided roughly equally between aziridines and epoxides, the twelve chapters discuss: * Synthesis of aziridines * Nucleophilic ring-opening of aziridines and epoxides * Organic synthesis with aziridine building blocks * Vinyl aziridines in organic synthesis * Diastereoselective aziridination reagents * Synthetic aspects of aziridinomitocene chemistry * Biosynthesis of biologically important aziridines * Organic catalysis of epoxide and aziridine ring formation * Metal-mediated synthesis of epoxides * Asymmetric epoxide ring opening chemistry * Epoxides in complex molecule synthesis * Biological activity of epoxide-containing molecules A high-quality reference manual for academic and industrial chemists alike.

Aziridines and Epoxides in Organic Synthesis

Aziridines and Epoxides in Organic Synthesis PDF Author: Andrei K. Yudin
Publisher: John Wiley & Sons
ISBN: 352760748X
Category : Science
Languages : en
Pages : 516

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Book Description
Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons. Besides their importance as reactive intermediates, many biologically active compounds also contain these three-membered rings. Filling a gap in the literature, this clearly structured book presents the much needed information in a compact and concise way. The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth. Divided roughly equally between aziridines and epoxides, the twelve chapters discuss: * Synthesis of aziridines * Nucleophilic ring-opening of aziridines and epoxides * Organic synthesis with aziridine building blocks * Vinyl aziridines in organic synthesis * Diastereoselective aziridination reagents * Synthetic aspects of aziridinomitocene chemistry * Biosynthesis of biologically important aziridines * Organic catalysis of epoxide and aziridine ring formation * Metal-mediated synthesis of epoxides * Asymmetric epoxide ring opening chemistry * Epoxides in complex molecule synthesis * Biological activity of epoxide-containing molecules A high-quality reference manual for academic and industrial chemists alike.

Manganese Catalysis in Organic Synthesis

Manganese Catalysis in Organic Synthesis PDF Author: Jean-Baptiste Sortais
Publisher: John Wiley & Sons
ISBN: 3527347305
Category : Technology & Engineering
Languages : en
Pages : 372

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Book Description
Manganese Catalysis in Organic Synthesis A must-read reference for anyone interested in catalyst design and sustainable organic synthesis In Manganese Catalysis in Organic Synthesis, distinguished researcher Jean-Baptiste Sortais delivers an insightful and robust overview of the use of manganese in homogenous catalysis. The editor includes papers from authoritative academics describing the organometallic precursors used to develop manganese catalysts and covers critical applications in organic synthesis, including reduction to oxidation reactions, C-C, C-N, C-X bond formation reactions, cross-coupling reactions, C-H bond activation to dihydroxylation and epoxidation reactions. Manganese Catalysis in Organic Synthesis is a practical resource for every organic chemist in academia and industry with an interest in non-noble metal catalysis, organic synthesis, and sustainable chemistry. It is intuitively and clearly organized, covering the most important synthetic procedures using homogenous manganese catalysts. It is also the ideal companion to works like Cobalt Catalysis in Organic Synthesis, Nickel Catalysis in Organic Synthesis, and Iron Complexes in Catalysis. Readers will also enjoy: Thorough introductions to organometallic manganese compounds in organic synthesis and manganese-catalyzed hydrogenation and hydrogen transfer reactions A comprehensive exploration of manganese-catalyzed hydrogen borrowing reactions and dehydrogenative coupling reactions Practical discussions of manganese-catalyzed hydrosilylation and hydroboration reactions and manganese-catalyzed electro- and photocatalysis transformations In-depth examinations of manganese-catalyzed C-H oxygenation reactions and manganese-catalyzed organometallic C-H activation Insightful treatments of manganese-catalyzed cross-coupling processes and manganese(III) acetate mediated cyclizations Perfect for catalytic, organic, and pharmaceutical chemists, Manganese Catalysis in Organic Synthesis deserves a place in the libraries of researchers and professionals interested in catalyst design and sustainable organic synthesis.

Asymmetric Synthesis of Three-Membered Rings

Asymmetric Synthesis of Three-Membered Rings PDF Author: Hélène Pellissier
Publisher: John Wiley & Sons
ISBN: 3527341145
Category : Science
Languages : en
Pages : 606

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Book Description
The first handbook to focus on the asymmetric synthesis of different types of three-membered rings. The outstanding and experienced authors have an excellent international reputation and cover cyclopropanes, epoxides and aziridines as well as chiral oxaziridines in equal measure. To this end, they describe in detail different synthetic approaches starting with chiral substrates as well as the application of chiral metal- or organocatalysts. Furthermore, methods for the kinetic resolution of initially racemic products are treated alongside recent advances and novel developments in established techniques for the synthesis of three-membered rings. With its structured composition this is of high interest to scientists in methodological and natural product synthesis as well as those in industrial and pharmaceutical chemistry.

Strategic Applications of Named Reactions in Organic Synthesis

Strategic Applications of Named Reactions in Organic Synthesis PDF Author: Laszlo Kurti
Publisher: Elsevier
ISBN: 0080575412
Category : Science
Languages : en
Pages : 808

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Book Description
Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. - The first reference work on named reactions to present colored schemes for easier understanding - 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples - An opening list of abbreviations includes both structures and chemical names - Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works - Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools - Extensive index quickly locates information using words found in text and drawings

Solvent-free Organic Synthesis

Solvent-free Organic Synthesis PDF Author: Koichi Tanaka
Publisher: John Wiley & Sons
ISBN: 3527626425
Category : Science
Languages : en
Pages : 468

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Book Description
In this second edition of a best-selling handbook all the chapters have been completely revised and updated, while four completely new chapters have been added. In order to meet the needs of the practitioner, emphasis is placed on describing precisely the technology and know-how involved. Adopting a didactic and comprehensible approach, the book guides the reader through theory and applications, thus ensuring its warm welcome among the scientific community. An excellent, essential and exhaustive overview.

Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition

Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition PDF Author: Maria Elizabeth Tiritan
Publisher:
ISBN: 9783039362394
Category :
Languages : en
Pages : 346

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Book Description
This book includes both fundamental studies and applications in a multidisciplinary research field involving a high diversity of chiral compounds, including commercial substances with industrial applications, pharmaceuticals, and new chiral compounds with promising biological activities. Recent developments and innovative approaches to producing enantiomerically pure compounds of industrial and research interest are included. Enantiomeric separation in both the analytical and preparative scale, determination of the enantiomeric purity, insights into enantioselective synthesis and many different aspects of chiral recognition, including chiral sensors, recognition in biological systems, and in analytical methods, are presented. Original research and review articles show the broad scope of chirality in diverse analytical fields and the connection to enantioselective synthesis and biological activities.

Synthesis of 4- to 7-membered Heterocycles by Ring Expansion

Synthesis of 4- to 7-membered Heterocycles by Ring Expansion PDF Author: Matthias D’hooghe
Publisher: Springer
ISBN: 3319249606
Category : Science
Languages : en
Pages : 376

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Book Description
The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.

Tellurium in Organic Synthesis

Tellurium in Organic Synthesis PDF Author: Nicola Petragnani
Publisher: Elsevier
ISBN: 0080474926
Category : Science
Languages : en
Pages : 400

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Book Description
The increasing number of publications that use tellurium clearly demonstrates the important role of tellurium compounds as unique and powerful tools in a broad range of organic chemical manipulations, often characterized by their selective behavior. Tellurium in Organic Synthesis provides an overview of the principal aspects of organic tellurium chemistry. Many chapters have been enriched and updated in this second edition. New chapters include overviews of toxicology and pharmacology and a review on the preparation and reactivity of several tellurium heterocycles. The first part of the book focuses on the preparation of selected inorganic tellurium compounds and on the main classes of organotellurium compounds. The second part, and main interest of the book, details the use of these inorganic and organic compounds as reagents to perform specific organic manipulations and synthesis. Reactions covered include reduction, formation and reaction of anionic species, deprotection, tellurium cyclizations, formation of alkenes, use of vinyllic tellurides, free radical chemistry, transmetallations, and removal of tellurium. - Overview of inorganic and organic tellurium chemistry - Synthetic applications of tellurium compounds - All topics accompanied by detailed experimental procedures

Classics in Stereoselective Synthesis

Classics in Stereoselective Synthesis PDF Author: Erick M. Carreira
Publisher: John Wiley & Sons
ISBN: 9783527324521
Category : Science
Languages : en
Pages : 664

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Book Description
Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.