Assessment of Image Quality Requirements in Magnetic Resonance Imaging for Quantitative Brain Morphometry PDF Download
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Author: Pavel Falkovskiy
Publisher:
ISBN:
Category :
Languages : en
Pages : 107
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Book Description
Mots-clés de l'auteur: magnetic resonance imaging ; structural MRI ; accelerated MPRAGE protocols ; brain morphometry analysis ; reproducibility of brain volume measurements.
Author: Pavel Falkovskiy
Publisher:
ISBN:
Category :
Languages : en
Pages : 107
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Book Description
Mots-clés de l'auteur: magnetic resonance imaging ; structural MRI ; accelerated MPRAGE protocols ; brain morphometry analysis ; reproducibility of brain volume measurements.
Author: Nicole Seiberlich
Publisher: Academic Press
ISBN: 0128170581
Category : Computers
Languages : en
Pages : 1094
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Book Description
Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author: Donglai Huo
Publisher:
ISBN:
Category :
Languages : en
Pages : 186
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Book Description
Author: Luigi Landini
Publisher: CRC Press
ISBN: 1420028669
Category : Technology & Engineering
Languages : en
Pages : 632
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Book Description
The popularity of magnetic resonance (MR) imaging in medicine is no mystery: it is non-invasive, it produces high quality structural and functional image data, and it is very versatile and flexible. Research into MR technology is advancing at a blistering pace, and modern engineers must keep up with the latest developments. This is only possible with a firm grounding in the basic principles of MR, and Advanced Image Processing in Magnetic Resonance Imaging solidly integrates this foundational knowledge with the latest advances in the field. Beginning with the basics of signal and image generation and reconstruction, the book covers in detail the signal processing techniques and algorithms, filtering techniques for MR images, quantitative analysis including image registration and integration of EEG and MEG techniques with MR, and MR spectroscopy techniques. The final section of the book explores functional MRI (fMRI) in detail, discussing fundamentals and advanced exploratory data analysis, Bayesian inference, and nonlinear analysis. Many of the results presented in the book are derived from the contributors' own work, imparting highly practical experience through experimental and numerical methods. Contributed by international experts at the forefront of the field, Advanced Image Processing in Magnetic Resonance Imaging is an indispensable guide for anyone interested in further advancing the technology and capabilities of MR imaging.
Author: L. Tugan Muftuler
Publisher: Taylor & Francis
ISBN: 1439852685
Category : Medical
Languages : en
Pages : 496
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Book Description
In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, th
Author: Alonso Cárdenas de la Parra
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
"Magnetic resonance imaging (MRI) is a non-invasive imaging technique commonly used to study neurological changes associated with disease. Morphometric analysis of MRI focuses on the quantitative analysis of size and shape of regions within the brain, thus providing a powerful tool for observing neurological changes. While many image processing tools have been developed for morphometric analyses, most have been designed with the adult population in mind. However, numerous diseases and disorders present themselves during childhood, and pediatric neuroimaging studies can help us better characterize them, aiding in understanding their etiology and progression, and providing information for better diagnostic tools. Pediatric neuroimaging studies present a series of unique challenges due to the normal neurodevelopment occurring during childhood and adolescence, with the brain undergoing substantial changes in size, shape, and maturation. The primary objective of this thesis is to design, test and validate morphometric techniques for pediatric neuroimaging studies. The first proposed technique focuses on early childhood (6-24 months of age), and consists of the application of tensor-based morphometry (TBM) by using T1 and T2-weighted scans simultaneously for the non-linear registration of scans to better account for the normal contrast changes that occur in this age range, as well as using age-appropriate templates as the target for this registration. This technique was applied to the study of autism spectrum disorder (ASD), with the results showing distinct differences in the growth trajectories of children with ASD when compared to controls in several regions across the brain. The second proposed technique focuses on later childhood and adolescence (4-23 years of age) and consists of a morphometric normalization technique that uses a large longitudinal normative database to establish normal growth trajectories for the volume of several regions in the brain, as well as at the voxel level. This technique was applied to study 16p11.2 copy number variants, with the results showing significant differences for the duplication and deletion cohorts already present at 4.5 years of age and remaining stable throughout childhood and adolescence. Finally, we propose an extension of this normalization technique that includes the addition of a second normative dataset and improved preprocessing, enabling normalization in studies with data acquired at both 1.5 and 3 T. This technique was applied to study pediatric onset multiple sclerosis (MS), with the results showing a lack of age expected growth in the MS patients in overall brain volume, and specifically in the thalamus, putamen, and globus pallidus"--
Author: Lara A. Brandao
Publisher: Elsevier Health Sciences
ISBN: 1455772011
Category : Medical
Languages : en
Pages : 549
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Book Description
Magnetic Resonance Spectroscopy (MRS) is an analytical method used in chemistry that enables the identification and quantification of metabolites in samples. It differs from conventional Magnetic Resonance Imaging in that spectra provide physiological and chemical information instead of anatomy. This issue examines MRS methods for a wide variety of body imaging needs.
Author: Ali Ghayoor
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 157
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Book Description
This work explores if combining information from multiple Magnetic Resonance Imaging (MRI) modalities provides improved interpretation of brain biological architecture as each MR modality can reveal different characteristics of underlying anatomical structures. Structural MRI provides a means for high-resolution quantitative study of brain morphometry. Diffusion-weighted MR imaging (DWI) allows for low-resolution modeling of diffusivity properties of water molecules. Structural and diffusion-weighted MRI modalities are commonly used for monitoring the biological architecture of the brain in normal development or neurodegenerative disease processes. Structural MRI provides an overall map of brain tissue organization that is useful for identifying distinct anatomical boundaries that define gross organization of the brain. DWI models provide a reflection of the micro-structure of white matter (WM), thereby providing insightful information for measuring localized tissue properties or for generating maps of brain connectivity. Multispectral information from different structural MR modalities can lead to better delineation of anatomical boundaries, but careful considerations should be taken to deal with increased partial volume effects (PVE) when input modalities are provided in different spatial resolutions. Interpretation of diffusion-weighted MRI is strongly limited by its relatively low spatial resolution. PVE's are an inherent consequence of the limited spatial resolution in low-resolution images like DWI. This work develops novel methods to enhance tissue classification by addressing challenges of partial volume effects encountered from multi-modal data that are provided in different spatial resolutions. Additionally, this project addresses PVE in low-resolution DWI scans by introducing a novel super-resolution reconstruction approach that uses prior information from multi-modal structural MR images provided in higher spatial resolution.
Author: Christine Lucas Tardif
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Sergey Kotov
Publisher:
ISBN:
Category : Technology
Languages : en
Pages :
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Book Description
The diagnosis of diseases of the brain is based on additional methods, confirming the clinical diagnosis. One of the most objective methods is magnetic resonance imaging (MRI). A detailed quantitative evaluation became possible after the introduction of MRI voxel-morphometry-statistical analysis of structural MRI images using a computerized segmentation matter of the brain gray and white matter. The decrease in the volume of the brain, as a manifestation of cerebral atrophy, is a common feature of many neurological diseases. We performed a study of brain structures in multiple sclerosis, Parkinson's disease, and cerebrovascular diseases. In patients with multiple sclerosis the correlation was found between the score on a scale of Expanded Disability Status Scale and the total thickness of the cerebral cortex. In our study of the brain in Parkinson's disease, the amount of the substantia nigra was slightly lower than in the control. In patients with long-following Parkinson's disease, the volume of substantia nigra was significantly higher than in patients with early stage. The increased volume was determined by the accumulation of organic iron compounds as a sign of neurodegeneration.
