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Author: Chaudhery Mustansar Hussain
Publisher: Elsevier
ISBN: 0323954618
Category : Technology & Engineering
Languages : en
Pages : 644
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Book Description
Antimicrobial Materials and Coatings covers the properties, fabrication technologies, and applications of antimicrobial coatings and materials, with a focus on innovative antimicrobial nanomaterials. Due to the globally concerning issue of antimicrobial resistance and the evidence that nanomaterials are believed to have no or low potential for resistance development, considerable efforts have been directed to synthesizing and developing antibacterial coatings and nanomaterials for a range of applications. This book guides the reader through the key properties, fabrication technologies and various applications of antimicrobial coatings and materials, including applications in food packaging, biomedicine and public health, water treatment and decontamination. - Covers a range of antimicrobial coatings and materials, including thin films, nanocomposites, bioactive materials, and more - Explores key microbial sub-types - bacteria, viruses, and fungi – and maps the appropriate antimicrobial coating/material to each type, helping the reader select the best optimized material for their purposes - Reviews the benefits of innovative antimicrobial nanomaterials and nanocoatings in fighting antimicrobial resistance in a range of industries and environments
Author: Chaudhery Mustansar Hussain
Publisher: Elsevier
ISBN: 0323954618
Category : Technology & Engineering
Languages : en
Pages : 644
Get Book Here
Book Description
Antimicrobial Materials and Coatings covers the properties, fabrication technologies, and applications of antimicrobial coatings and materials, with a focus on innovative antimicrobial nanomaterials. Due to the globally concerning issue of antimicrobial resistance and the evidence that nanomaterials are believed to have no or low potential for resistance development, considerable efforts have been directed to synthesizing and developing antibacterial coatings and nanomaterials for a range of applications. This book guides the reader through the key properties, fabrication technologies and various applications of antimicrobial coatings and materials, including applications in food packaging, biomedicine and public health, water treatment and decontamination. - Covers a range of antimicrobial coatings and materials, including thin films, nanocomposites, bioactive materials, and more - Explores key microbial sub-types - bacteria, viruses, and fungi – and maps the appropriate antimicrobial coating/material to each type, helping the reader select the best optimized material for their purposes - Reviews the benefits of innovative antimicrobial nanomaterials and nanocoatings in fighting antimicrobial resistance in a range of industries and environments
Author: Alexandru Mihai Grumezescu
Publisher: William Andrew
ISBN: 0323527345
Category : Science
Languages : en
Pages : 578
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Book Description
Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy. - Provides readers with the information necessary to select the appropriate bionanomaterial to solve particular infection problems - Includes case studies, showing how particular bionanomaterials have been used to cure infections - Explains the central role that nanotechnology plays in modern antimicrobial therapy - Evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections
Author: Juan Bueno
Publisher: Springer Nature
ISBN: 3030438554
Category : Medical
Languages : en
Pages : 125
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Book Description
Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.
Author: Raymond J. Turner
Publisher: MDPI
ISBN: 3039438913
Category : Science
Languages : en
Pages : 252
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Book Description
There is some talk about an antibiotic Armageddon due to quickly developing resistance towards commercially available antibiotics. For the most part, the classical antibiotic pipeline has dried up, and antibiotic resistance to any new drugs quickly develops. It is here that metal-based antimicrobials can step forward as possible solutions in this antimicrobial resistance era. The biological targets of metal atoms are more diverse, thus making it more difficult for bacteria to develop resistance compared with classical antibiotics. The metal silver has been used since antiquity for wound healing and water purification. At present, it is the most prevalent antimicrobial metal used in healthcare, industry, and consumer products. Silver is being used in the form of ionic salt, colloids, or in specific nanomaterials, and as described in this book, it can be applied as mixtures with other antimicrobials or coating composites. The different formulations are explored for their efficacy against a variety of problems related to agricultural and medical infections. Whilst by no means exhaustive, this book nicely highlights the present directions in silver-based antimicrobial research and antimicrobial formulation development. The chapters have been organized from a general introductory review to approaches of mixing other antimicrobials and materials to enhance silver performance. This is followed by synthetic approaches. First are biogenic (sometimes called green or eco-friendly) approaches, followed by advanced physical–chemical synthetic approaches. The book ends with an overview of applications through a review of patents over the past 10 years.
Author: Alina Maria Holban
Publisher: William Andrew
ISBN: 0323477224
Category : Technology & Engineering
Languages : en
Pages : 972
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Book Description
Nanoarchitectonics for Smart Delivery and Drug Targeting is one of the first books on the market to exclusively focus on the topic of nanoarchitectonics, a rapidly developing area of nanotechnology which allows scientists to arrange nanoscale structural units, typically a group of atoms or molecules, in an intended configuration. This book assesses novel applications of nanomaterials in the areas of smart delivery and drug targeting using nanoarchitectonics and discusses the advantages and disadvantages of each application. - Provides a scholarly introduction to the uses of nanoarchitectonics in drug delivery and targeting - Explores novel opportunities and ideas for developing and improving nanoscale drug delivery systems through the use of nanoarchitectonics, allowing scientists to see how this exciting new technology is used in practice - Assesses the pros and cons of each application, allowing readers to assess when it is most appropriate to use nanoarchitectonics in drug delivery
Author: Anton Ficai
Publisher: Elsevier
ISBN: 0323461514
Category : Science
Languages : en
Pages : 724
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Book Description
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
Author: Hemant Kumar Daima
Publisher: CRC Press
ISBN: 1000399974
Category : Medical
Languages : en
Pages : 487
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Book Description
The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features: Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications Includes importance of nanotoxicity concepts in developing smart nanomaterials Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.
Author: Divya Bajpai Tripathy
Publisher: Bentham Science Publishers
ISBN: 9815256513
Category : Technology & Engineering
Languages : en
Pages : 279
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Book Description
Applications of Nanoparticles in Drug Delivery and Therapeutics is an authoritative review on nanoparticle-based drug delivery systems. This comprehensive volume focuses on the transformative role of nanoparticles in enhancing drug delivery systems and advancing therapeutic applications. By bridging the gap between laboratory research and clinical practice, this book offers a thorough exploration of how nanotechnology is revolutionizing the pharmaceutical industry. The book is structured into well-organized chapters, each dedicated to a specific aspect of nanoparticle-based drug delivery and therapy. Initial chapters provide a foundational understanding of nanoparticle synthesis, characterization, and functionalization. Subsequent sections cover various types of nanoparticles, including liposomes, dendrimers, and polymeric nanoparticles, highlighting their unique properties and applications. The latter chapters delve into case studies and clinical trials, showcasing real-world applications and the therapeutic potential of nanoparticle technologies in treating diseases like cancer, cardiovascular disorders, and neurodegenerative diseases. Key features of this book include detailed discussions on the design and optimization of nanoparticles for targeted drug delivery, insights into the regulatory and safety aspects of nanomedicine, and comprehensive reviews of current and emerging therapeutic applications. The book also offers practical guidance on the challenges and future directions in the field, making it an invaluable reference for researchers and practitioners alike. Chapters 1 and 2 are based on the introduction of nanomaterials used as drug delivery systems, their manufacturing approaches and applications. Chapters 3 and 4 emphasize on the use of nanoparticles in medical diagnostics and in intervention devices. Chapters 5 and 6 illustrate the use of lipids-based nanoparticles in medical imaging and drug delivery. Chapter 7 specifically discusses amino acid functionalized inorganic nanoparticles in diagnostics. Chapter 8 is focused on the special class of nanoparticles “hybrid nanocomposites”. Chapters 9 and 10 covers the applications of silica and fullerene nanomaterials in anticancer drug delivery. The book is intended as a resource for pharmaceutical scientists, biomedical researchers, and healthcare professionals keen on the latest advancements in drug delivery systems. It also serves as essential reading for graduate students and academics in pharmacology and medical courses that require learning about modern drug delivery systems.
Author: Munir Ozturk
Publisher: Elsevier
ISBN: 0323998437
Category : Technology & Engineering
Languages : en
Pages : 580
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Book Description
Synthesis of Bionanomaterials for Biomedical Applications summarizes a range of procedures, including green synthesis of metal nanoparticles, metal oxide nanoparticles, and other types of nanoparticles while also exploring the appropriate use of these nanoparticles in various therapeutic applications such as anticancer, antibacterial, antifungal, drug delivery, and more. The book provides important information for materials scientists and pharmaceutical scientists on the synthesis of various nanoparticles using a variety of eco-friendly bionanomaterials. As concern has arisen regarding the environmental impact caused by some of nanomaterials, as well as their possible toxicity to cells, this book presents information on a new generation of eco-friendly materials. In addition, the green synthesis of nanoparticles shows how environmentally-friendly nanoparticles can be synthesized from different biological sources, such as microbes, fungi, algae and plants. - Provides information on the synthesis and application of eco-friendly bionanomaterials - Offers coverage of nanomaterials generated through green synthesis - Assesses the challenges of manufacturing eco-friendly nanomaterials on an industrial scale
Author: Sanjay Mavinkere Rangappa
Publisher: Woodhead Publishing
ISBN: 0323853293
Category : Technology & Engineering
Languages : en
Pages : 552
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Book Description
Nanoparticle-Based Polymer Composites discusses recent advancements on the synthesis, processing, characterization and applications of this new class of hybrid materials. Chapters cover recycling and lifecycle assessment, with contributions from leading researchers in industry, academics, the government and private research institutes from across the globe. As nanoparticle-based polymer composites are now replacing traditional polymer composites in a broad range of applications such as fuel cells, electronic and biomedical devices, this book presents the latest advancements in the field.Studies have shown that incorporating metal nanoparticles in polymer matrices can improve their mechanical, thermal, electrical and barrier properties. The unique combination of these properties makes this new class of materials suitable for a broad range of different and advanced applications. - Features recent advancements on the synthesis, processing and characterization of nanoparticle-based polymer composites - Discusses recycling and lifecycle assessment - Highly application-orientated, with contributions from leading international researchers in industry, academia, the government and private research institutes
