Antimicrobial Peptides PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Antimicrobial Peptides PDF full book. Access full book title Antimicrobial Peptides by Katsumi Matsuzaki. Download full books in PDF and EPUB format.
Author: Katsumi Matsuzaki
Publisher: Springer
ISBN: 9811335885
Category : Medical
Languages : en
Pages : 300
Get Book Here
Book Description
This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.
Author: Katsumi Matsuzaki
Publisher: Springer
ISBN: 9811335885
Category : Medical
Languages : en
Pages : 300
Get Book Here
Book Description
This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.
Author: David A. Phoenix
Publisher: John Wiley & Sons
ISBN: 9783527332632
Category : Science
Languages : en
Pages : 0
Get Book Here
Book Description
In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.
Author: Luis F. Castillo
Publisher: Springer Science & Business Media
ISBN: 3319015680
Category : Technology & Engineering
Languages : en
Pages : 393
Get Book Here
Book Description
This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.
Author: Neil M. O’Brien-Simpson
Publisher: Frontiers Media SA
ISBN: 2889454703
Category :
Languages : en
Pages : 137
Get Book Here
Book Description
In 2014, the World Health Organization (WHO) listed cancer as the second leading cause of death and highlighted antimicrobial resistance as “a key global health challenge” that may, in a worst case scenario, lead to an annual death toll of 10 million by 2050, which would exceed predicted cancer deaths by 20%. Novel promising therapeutic options to reduce morbidity and mortality of both infectious microbial diseases and cancer are being developed based on antimicrobial peptides (AMPs), i.e., evolutionary proven antibiotics that also possess anti-cancer activities. Intriguingly, AMPs and anti-cancer peptides (ACPs) rely typically on novel mechanisms and cellular targets not used by current antibiotics or chemotherapeutics. Initiated by presentations at the International Meeting of Antimicrobial Peptides in 2016 (IMAP 2016), hosted at Leipzig University, Germany, this book compiles the most recent strategies and promising lead compounds for treating multi- and pan-resistant microbes and chemo-resistant cancer cells in fourteen different chapters representing leading research groups from five different continents. In this respect, the book shall stimulate new avenues of thinking and strategies in tackling forthcoming antimicrobial and cancer resistance health threats with the hope that the scenarios recently reported by the WHO will never eventuate.
Author: Iulia M. Lazar
Publisher: Humana
ISBN: 9781493984145
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
This book reflects the drug development community’s interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on select protocols and methodologies that address the analysis of post-translational modifications, targeted protein quantification, protein-protein, protein-lipid, or protein-ATP interactions, in silico lead identification, protein arrays, tissue and cell extract preparation, labeling, chemoproteomics, and drug efficacy assessment. Emphasis was placed not just on methods that describe large-scale protein analysis, but also on ones that are amenable to future implementation in a high-throughput format. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Proteomics for Drug Discovery: Methods and Protocols aims to provide a deep knowledge of the fundamentals of disease biology as well the means that were developed for probing the complex biological milieu.
Author: Surinder K. Mehta
Publisher: John Wiley & Sons
ISBN: 3527348689
Category : Science
Languages : en
Pages : 292
Get Book Here
Book Description
Metallosurfactants Provides up-to-date coverage of the synthesis, properties, and applications of metallosurfactants Metallosurfactants: From Fundamentals to Catalytic and Biomedical Applications is a thorough introduction to amphiphilic compounds that allow to incorporate metal ions in the surfactant system. This comprehensive reference and guide describes the fundamentals of metal surfactant complexes, highlights recent advances in the field, and explores current and future applications and research areas. Gradually progressing from basic to advanced topics, the authors first explain the classification and characterization of metallosurfactants before delving into more complex concepts and various catalytic, sensing, and biomedical applications. The book begins with coverage of the synthesis of metallosurfactants and their surface, interfacial, and aggregation behavior. Subsequent chapters discuss applications of metallosurfactants in areas such as drug delivery, molecular machines, transfection, nanoparticle synthesis, and carbon monoxide-releasing molecules (CORMs). Other topics include the use of metallosurfactants as catalysts in organic reactions, and as anticancer and antimicrobial agents in drug delivery and formulation. This unique reference Provides an overview of the structure-function relationship, synthesis methods, and characterization of metallosurfactants Reviews current trends in metallosurfactant development and research Examines the use of metallosurfactants in a wide range of reactions, including esterolytic reactions and hydrogen generation Discusses advanced applications of metallosurfactants, e.g. as nanoreactors for nanoparticle synthesis, non-viral transfection vectors, and sensors Metallosurfactants: From Fundamentals to Catalytic and Biomedical Applications is an excellent introduction to the growing field of metallosurfactant chemistry as well as a concise, highly useful reference for researchers and scientists in both academia and industry.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 8
Get Book Here
Book Description
Author: Ian W. Hamley
Publisher: John Wiley & Sons
ISBN: 1119698189
Category : Science
Languages : en
Pages : 238
Get Book Here
Book Description
Provides an interdisciplinary introduction to peptide science, covering their properties and synthesis, as well as many contemporary applications Peptides are biomolecules comprised of amino acids which play an important role in modulating many physiological processes in our body. This book presents an interdisciplinary approach and general introduction to peptide science, covering contemporary topics including their applicability in therapeutics, peptide hormones, amyloid structures, self-assembled structures, hydrogels, and peptide conjugates including lipopeptides and polymer-peptide conjugates. In addition, it discusses basic properties and synthesis clearly and concisely. Taking a logical approach to the subject, Introduction to Peptide Science gives readers the fundamental knowledge that is required to understand the cutting-edge material which comes later in the book. It offers readers in-depth chapter coverage of the basic properties of peptides; synthesis; amyloid and peptide aggregate structures; antimicrobial peptides and cell-penetrating peptides; and peptide therapeutics and peptide hormones. Introduces readers to peptide science, including synthesis and properties Provides unique content covering properties, synthesis, self-assembly, aggregation, and applications Summarizes contemporary topics in an accessible fashion including applications in therapeutics, peptide hormones, amyloid structures, self-assembled structures, hydrogels, and peptide conjugates including lipopeptides Presented at an introductory level for the benefit of students and researchers who are new to the subject Introduction to Peptide Science is an ideal text for undergraduate students of chemistry, biochemistry, and other related biological subjects, and will be a valuable resource for postgraduate students and researchers involved in peptide science and its applications.
Author: Sudhir P. Singh
Publisher: John Wiley & Sons
ISBN: 1119717248
Category : Science
Languages : en
Pages : 452
Get Book Here
Book Description
Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance. The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader’s knowledge of the applications of different microbial diversity and reveal new avenues of research investigation. Readers will also benefit from: A thorough introduction to microbial biodiversity and bioprospecting An exploration of anti-ageing and skin lightening microbial products and microbial production of anti-cancerous biomolecules A treatment of UV protective compounds from algal biodiversity and polysaccharides from marine microalgal sources Discussions of microbial sources of insect toxic proteins and the role of microbes in bio-surfactants production Perfect for academics, scientists, researchers, graduate and post-graduate students working and studying in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology, Bioprospecting of Microorganism-Based Industrial Molecules is an indispensable guide for anyone looking for a comprehensive overview of the subject.
Author: Anton Ficai
Publisher: Elsevier
ISBN: 0323461514
Category : Science
Languages : en
Pages : 724
Get Book Here
Book Description
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
