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Author: Juan José Torrado Durán
Publisher: MDPI
ISBN: 3039363069
Category : Science
Languages : en
Pages : 168
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Book Description
Fungal and parasitic diseases affect more than one billion people across the globe. This is one-sixth of the world´s population, mostly located in developing countries. The lack of effective and safe treatments, combined with inefficient diagnosis, leads to serious chronic illness or even death. There is a discrepancy between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind the poor water solubility that limits their bioavailability and efficacy. There is an unmet clinical need to develop vaccines, novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effects by enhancing their dissolution, increasing their chemical potency, stabilizing the drug and targeting high concentrations of the drug to infection sites. This Special Issue includes ten research articles of antifungal and antiparasitic drug delivery systems.
Author: Juan José Torrado Durán
Publisher: MDPI
ISBN: 3039363069
Category : Science
Languages : en
Pages : 168
Get Book Here
Book Description
Fungal and parasitic diseases affect more than one billion people across the globe. This is one-sixth of the world´s population, mostly located in developing countries. The lack of effective and safe treatments, combined with inefficient diagnosis, leads to serious chronic illness or even death. There is a discrepancy between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind the poor water solubility that limits their bioavailability and efficacy. There is an unmet clinical need to develop vaccines, novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effects by enhancing their dissolution, increasing their chemical potency, stabilizing the drug and targeting high concentrations of the drug to infection sites. This Special Issue includes ten research articles of antifungal and antiparasitic drug delivery systems.
Author: Juan José Torrado Durán
Publisher:
ISBN: 9783039363070
Category :
Languages : en
Pages : 168
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Book Description
Author: Prashant Kesharwani
Publisher: Elsevier
ISBN: 0443151792
Category : Medical
Languages : en
Pages : 443
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Book Description
Higee Chemical Reaction Engineering systematically discusses the fundamentals, principles and methods of molecular mixing and reaction process intensification. The book demonstrates in detail the implementation approach, process and effectiveness of Higee chemical reaction engineering through novel industrial case studies that help industrial technicians to select reaction intensification technology route more scientifically. The book covers the innovation and development process of Higee chemical reaction engineering, hydrodynamics behavior in Higee reactors, equipment design principles and methods, multiphase reaction of liquid-liquid, gas-liquid, gas-solid, gas-liquid-solid and reactive crystallization process intensification principles and effectiveness. It also prospects the future development direction and hot application fields of Higee chemical reaction process intensification. Higee Chemical Reaction Engineering is a systematic summary of several national award and key projects, such as the State Technological Innovation Award, State Science and Technology Advancement Award, National Natural Science Foundation of China, National key R&D Program of China, National ''863'' Program of China, National ''973'' Program of China and also some international cooperation. - Handles high gravity process intensification technology - Covers theoretical innovation in multiphase reaction intensified by high gravity - Presents engineering application cases in chemical engineering, materials science, ocean engineering, and environmental engineering - Provides systematic understanding of high gravity process intensification through theories and industrial applications
Author: M. Lindsay Grayson
Publisher: CRC Press
ISBN: 1498747965
Category : Medical
Languages : en
Pages : 4894
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Book Description
Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.
Author: Mahmoud Ghannoum
Publisher: CRC Press
ISBN: 0849387868
Category : Medical
Languages : en
Pages : 484
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Book Description
A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c
Author: Mary Lee
Publisher: ASHP
ISBN: 1585281360
Category : Medical
Languages : en
Pages : 539
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Book Description
Tying together concepts of traditional pharmaceutics in a way this text focuses on the selection of appropriate dosage forms as an integral part of drug therapy.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309672104
Category : Medical
Languages : en
Pages : 427
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Book Description
Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events.
Author: Jill E. Maddison
Publisher: Elsevier Health Sciences
ISBN: 0702037257
Category : Medical
Languages : en
Pages : 600
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Book Description
The eBook version of this title gives you access to the complete book content electronically*. Evolve eBooks allows you to quickly search the entire book, make notes, add highlights, and study more efficiently. Buying other Evolve eBooks titles makes your learning experience even better: all of the eBooks will work together on your electronic "bookshelf", so that you can search across your entire library of Veterinary Medicine eBooks. *Please note that this version is the eBook only and does not include the printed textbook. Alternatively, you can buy the Text and Evolve eBooks Package (which gives you the printed book plus the eBook). Please scroll down to our Related Titles section to find this title. Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. - Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance - Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders - Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject - All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text
Author: Shrikaant Kulkarni
Publisher: Springer Nature
ISBN: 9819952816
Category : Medical
Languages : en
Pages : 298
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Book Description
The book gives an insight into the theoretical background, conceptual understanding, latest developments, and applications in the field of pharmaceuticals in general and drug design, discovery, biosystems, and biomedical and drug delivery technologies in particular. Knowledge is drawn from various disciplines such as Chemistry, Biology, Material Science and Engineering, Statistics, Biomedicine, and Genetics . A host of applications like bio-imaging, novel biological agents, testing, characterization and validation of drugs, computer-based models in drug design, and application of statistical tools in data analysis, design, and development of drug delivery systems, and ecosystems are dealt with in detail. The said book undoubtedly confirms the requirements of the postgraduate students, research scholars, academicians, scientists, and researchers from the academia, pharmaceutical, biotechnology, and chemical engineering domain. The book covers a conceptual understanding of the exploration of drugs in tandem with intended uses, sound ecosystem development, and carriers for drug and supplement delivery.
Author: William C. Campbell
Publisher: Springer Science & Business Media
ISBN: 1461236266
Category : Medical
Languages : en
Pages : 380
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Book Description
Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a veterinary antiparasitic drug and agricultural pesticide, respectively. Their acceptance and commercial success have been remarkable; both are highly effective and in worldwide use. The efficacy of ivermectin in river blindness has expanded the interest in its use in human medicine. In response to the intense scientific and industrial interest in ivermectin and abamectin and the likelihood that they will be forerunners of an expanding family of drugs, this comprehensive monograph satisfies the need for a review and synthesis of current knowledge about the use of these substances in crop protection as well as in cattle, sheep, swine, horses, dogs, cats, birds, fish, reptiles, and in man. This overview presents chemical, biochemical, and microbiological data, as well as pharmacological, safety, and environmental aspects and covers practical use of the compounds as antiparasitic and pesticide agents, as well as the available safety data that have emerged from the clinical experience with human applications.
