Animal Transgenesis and Cloning PDF Download
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Author: Louis-Marie Houdebine
Publisher: Wiley-Blackwell
ISBN:
Category : Medical
Languages : en
Pages : 248
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Book Description
Designed to be a concise, balanced introduction to this dynamic subject, covering key issues and current techniques currently used in animal transgenesis and cloning. Provides the essentials of the subject, from the molecular basis of gene structure and function to therapeutic gene cloning in humans. Social and ethical implications of this important area of research are also considered.
Author: Louis-Marie Houdebine
Publisher: Wiley-Blackwell
ISBN:
Category : Medical
Languages : en
Pages : 248
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Book Description
Designed to be a concise, balanced introduction to this dynamic subject, covering key issues and current techniques currently used in animal transgenesis and cloning. Provides the essentials of the subject, from the molecular basis of gene structure and function to therapeutic gene cloning in humans. Social and ethical implications of this important area of research are also considered.
Author: Keywon Frazier
Publisher: Scientific e-Resources
ISBN: 1839474432
Category :
Languages : en
Pages : 276
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Book Description
Transgenic methodologies continue to evolve and have dramatically influenced a cross section of disciplines. They are recognized as instrumental in expanding our understanding of gene expression, regulation and function. This book covers the aspects of gene transfer in animals-from molecular methods to whole animal considerations across a host of species. The book starts with an introduction of what are transgenic animals. Chapter 1 methods and applications related to transgenic application. Chapter 2 describes the Use of Transgenic Animals in Biotechnology as Prospects and Problems. Chapter 3 study about Transgenic Animals in Agriculture. Chapter 4 depicts about the Gene Replacement and Transgenic Animals. This chapter give insight on Specific Sites in Cloned Genes Can Be Altered in Vitro and DNA that can be transferred into Eukaryotic Cells in Various Ways. Chapter 5 discuss about basics of cloning. Chapter 6 tells about the Reproductive Cloning. Chapter 7 tells about the Cloning of Domestic Animals. Chapter 8 depicts about the Surface Epigenetic Reprogramming. Chapters 9 devoted to Animal Health Risks. This chapter focus on the critical biological systems approach to the analysis of clone animal. Chapter 10 describes the development of the Risk Assessment Methodology required for cloning.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309084393
Category : Technology & Engineering
Languages : en
Pages : 201
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Book Description
Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309166152
Category : Science
Languages : en
Pages : 254
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Book Description
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309076374
Category : Science
Languages : en
Pages : 295
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Book Description
Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.
Author: R. Renaville
Publisher: Springer Science & Business Media
ISBN: 0306468875
Category : Science
Languages : en
Pages : 360
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Book Description
Animal biotechnology is a broad umbrella encompassing the polarities of fundamental and applied research including molecular modelling, molecular and quantitative genetics, gene manipulation, development of diagnostics and vaccines and manipulation of tissue or digestion metabolism by growth promoters. Although animal biotechnology in the broadest sense is not new, what is new is the level of complexity and precision involved in scientists' current ability to manipulate living organisms. This new book sets out to show that the important ideas in animal biotechnology are exciting and relevant to everyday experience. It represents an important update of the literature for research workers, lecturers, and advisers in animal science, but is also a core text for advanced undergraduate courses in animal science and biotechnology. It will be an essential acquisition for librarians in agriculture and veterinary science.
Author: Louis-Marie Houdebine
Publisher: Springer Science & Business Media
ISBN: 9048122279
Category : Medical
Languages : en
Pages : 135
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Book Description
Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.
Author: Shirley Pease
Publisher: Springer Nature
ISBN: 3642207928
Category : Science
Languages : en
Pages : 671
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Book Description
This laboratory manual, published in cooperation with the International Society for Transgenic Technology (ISTT), provides almost all current methods that can be applied to the creation and analysis of genetically modified animals. The chapters have been contributed by leading scientists who are actively using the technology in their laboratories. Based on their first-hand experience the authors also provide helpful notes and troubleshooting sections. Topics range from standard techniques, such as pronuclear microinjection of DNA, to more sophisticated and modern methods, such as the derivation and establishment of embryonic stem (ES) cell lines, with defined inhibitors in cell culture medium. In addition, related topics with relevance to the field are addressed, including global web-based resources, legal issues, colony management, shipment of mice and embryos, and the three R’s: refinement, reduction and replacement.
Author: Saurabh Bhatia
Publisher:
ISBN: 9780750319652
Category :
Languages : en
Pages : 320
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Book Description
Animal biotechnology is a broad field including polarities of fundamental and applied research, as well as DNA science, covering key topics of DNA studies and its recent applications. In Introduction to Pharmaceutical Biotechnology, DNA isolation procedures followed by molecular markers and screening methods of the genomic library are explained in detail. Interesting areas such as isolation, sequencing and synthesis of genes, with broader coverage of the latter, are also described. The book begins with an introduction to biotechnology and its main branches, explaining both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It then moves on to the historical development and scope of biotechnology with an overall review of early applications that scientists employed long before the field was defined. Additionally, this book offers first-hand accounts of the use of biotechnology tools in the area of genetic engineering and provides comprehensive information related to current developments in the following parameters: plasmids, basic techniques used in gene transfer, and basic principles used in transgenesis. The text also provides the fundamental understanding of stem cell and gene therapy, and offers a short description of current information on these topics as well as their clinical associations and related therapeutic options.
Author: Joseph Panno
Publisher: Infobase Publishing
ISBN: 081606735X
Category : Biology
Languages : en
Pages : 177
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Book Description
Examines the scientific, legal, and ethical issues surrounding animal cloning technology.
