Buruli Ulcer PDF Download
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Author: Gerd Pluschke
Publisher: Springer
ISBN: 3030111148
Category : Medical
Languages : en
Pages : 290
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Book Description
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
Author: Gerd Pluschke
Publisher: Springer
ISBN: 3030111148
Category : Medical
Languages : en
Pages : 290
Get Book Here
Book Description
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
Author: Lawrence S. Chan
Publisher: CRC Press
ISBN: 9781135510275
Category : Medical
Languages : en
Pages : 584
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Book Description
Progress in understanding skin diseases has been aided enormously by the use of tissues derived from animals, by studying normal processes in animals, and by the development of animal models. The cellular activities in animals and humans are remarkably similar and the actual pathological process of an inflammatory skin disease can only be accurately observed and analyzed in a living animal model, and not in any in vitro model system. These factors have led to the regular use of animal tissues and models to allow the disease processes to be studied at a much greater depth. Animal Models of Human Inflammatory Skin Diseases features the principles and practices of how to go about studying inflammatory skin diseases using live animal models. On the principle side, the book describes the comparative structure and function of the skin, and the comparative immunology system in animal species commonly used as models. From the practical perspective, it presents a general discussion on methods of experimental animal modeling and contains specific expert experience on individual models. The authors include a detailed method of disease induction for each model, present chapters on comparative histology and immunology, and discuss potential targets of disease intervention. Written by biomedical investigators with first-hand experience in their chosen fields, this book is a valuable guide and reference for investigators in the biomedical and pharmaceutical sciences. It provides an instantaneous comparison between the skin structure and immunology of humans and animals, aiding in the interpretation and application of pathologic and immunologic findings.
Author: John P. Sundberg
Publisher: CRC Press
ISBN: 9780849383724
Category : Medical
Languages : en
Pages : 582
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Book Description
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0128096993
Category : Medical
Languages : en
Pages : 1200
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Book Description
Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. Offering easily searchable advantages and disadvantages for each animal model and organized by disease topics, this resource aids researchers in finding the best animal model for research in human disease. - Organized by disease orientation for ease of searchability - Provides information on locating resources, animal alternatives, and animal ethics - Covers a broad range of animal models used in research for human disease - Contributed by leading experts across the globe - Expanded coverage of diabetes and neurological diseases
Author: Chao Ma
Publisher: Humana Press
ISBN: 9781607618799
Category : Medical
Languages : en
Pages : 0
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Book Description
With the loss of work days, the price of health care and payments for compensation, litigation, and malpractice, and the overwhelming cost of human suffering, chronic pain syndromes affect humanity enormously on both an economic and personal level. In Animal Models of Pain, expert investigators in the field provide a consolidated review of the current state of pain research by capturing the diversity of animal models that are used to investigate pain mechanisms, which range from surgical incision to mechanical compression and from spinal cord injury to cutaneous/local inflammation and beyond. As a volume in the respected Neuromethods series, this book delivers its vital content through detailed descriptions of a wide variety of step-by-step laboratory methods. Authoritative and cutting-edge, Animal Models of Pain seeks to lead scientists closer to the ultimate goal of improving the quality of life and relieving the unbearable burden of chronic pain for millions of people throughout the world.
Author: E. Carstens
Publisher: CRC Press
ISBN: 1466505435
Category : Science
Languages : en
Pages : 482
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Book Description
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
Author: Thomas Ruzicka
Publisher: Springer Science & Business Media
ISBN: 3662026716
Category : Medical
Languages : en
Pages : 491
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Book Description
State-of-the-art review on atopic eczema, one of the most common skin diseases today. This multi-authored handbook covers all aspects relevant for physicians from various disciplines.
Author: Bartholomew Ibeh
Publisher: BoD – Books on Demand
ISBN: 1789231647
Category : Science
Languages : en
Pages : 410
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Book Description
The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.
Author: Wolfram Sterry
Publisher: Thieme
ISBN: 1604061456
Category : Medical
Languages : en
Pages : 776
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Book Description
Dermatology, the first book in the new Thieme Clinical Companions series, presents the essential information on how to diagnose and treat the full range of dermatologic diseases.Compiled by expert physicians, this pocket guide describes the diagnostic approach and therapeutic options for a wide range of skin diseases. More than 300 full-color illustrations, diagrams, checklists, charts, and clinical tips illuminate all concepts and techniques described in the text. Basic aspects of skin biology and disease pathophysiology are also covered.To aid quick reference and review, the book is organized into the following color-coded sections: Introduction and Diagnosis: A concise overview of the biology and anatomy of the skin, followed by a step-by-step guide to the dermatologic evaluation. Dermatologic Diseases: Extensive coverage of skin and hair disorders, with illustrations and essential information for each, including pathogenesis, clinical features, diagnostic approach, differential diagnosis, therapy, and more. Therapy: Review of the current information on establishing a treatment plan, including topical, systemic, and radiation therapy, as well as operative dermatology, wound healing, and emergency treatment. Useful Appendices: Common systemic medications and commonly used compounding recipes Dermatologic Differential Diagnosis: Comprehensive charts (with numerous cross-references) designed to help the reader recognize and fully understand the patient's signs and symptoms. All dermatologists, residents, and trainees will benefit from keeping this compact portable guide on hand in the clinical setting.
Author: Christopher S. Stevenson
Publisher: Springer Science & Business Media
ISBN: 3764377607
Category : Medical
Languages : en
Pages : 210
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Book Description
In Vivo Models of Inflammation (Vol. 2) provides biomedical researchers in both the pharmaceutical industry and academia with a description of the state-of-the-art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first, describing and updating the standard models that are most utilized for specific disease areas. New models are included exploring emerging areas of inflammation research.
