Author: Chun Y. Seow
Publisher: Cambridge Scholars Publishing
ISBN: 152756228X
Category : Medical
Languages : en
Pages : 189
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Book Description
This second edition is an updated version of an introductory level textbook intended for students who are interested in understanding the mechanical properties of smooth muscle. Compared with skeletal and cardiac muscles, smooth muscle is the least understood in terms of its contraction mechanism and the structure of its contractile apparatus. Nevertheless, it is an important tissue that is vital in many organ functions, such as blood pressure control, intestinal peristalsis, and the emptying of the bladder. Dysfunction of the muscle has been implicated in many diseases such as high blood pressure, asthma, and overactive bladders. This is the only book-length treatment of functional models of a variety of smooth muscle behaviors with their corresponding mathematical descriptions, and offers an easy-to-follow, step-by-step mathematical derivation that will help students to appreciate the muscle cell as a fine-tuned aggregate of mechanisms governed by the fundamental laws of physics. In addition to providing a detailed description of the known subcellular structure and mechanical function of the contractile apparatus of smooth muscle, it also covers experimentation techniques, instrumentation, and data analysis. The book is a must-have information source for anyone interested in smooth muscle cell ultrastructure, physiology, biochemistry, and pharmacology.
Author: Lindsay Biga
Publisher:
ISBN: 9781955101158
Category :
Languages : en
Pages :
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Book Description
A version of the OpenStax text
Author: Joseph Hill
Publisher: Academic Press
ISBN: 012381510X
Category : Medical
Languages : en
Pages : 1469
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Book Description
Muscle: Fundamental Biology and Mechanisms of Disease will be the first reference covering cardiac, skeletal, and smooth muscle in fundamental, basic science, translational biology, disease mechanism, and therapeutics. Currently there are no publications covering the science behind the medicine, as the majority of books are 90% clinical and 10% science. Muscle: Fundamental Biology and Mechanisms of Disease will discuss myocyte biology, also known as muscle cell biology, providing information about the science behind clinical work and therapeutics with a 90% science and 10% clinical focus. A needed resource for researchers, clinical professionals, postdocs, and graduate students, this publication will further discuss basic biology development and physiology, how processes go awry in disease states, and how the defective pathways are targeted for therapy. This book will assist both the new and experienced clinician's and researcher's need for science translation of background research into clinical applications, bridging the gap between research and clinical knowledge.
Author: Henry P. Parkman
Publisher: Springer Science & Business Media
ISBN: 1607615525
Category : Medical
Languages : en
Pages : 425
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Book Description
Gastroparesis is an increasingly recognized disorder. Treatment can be difficult due to the several mechanisms for symptom production. Gastroparesis: Pathophysiology, Presentation and Treatment serves as a concise reference on this disorder that allows clinicians to quickly access and evaluate the necessary information for treating and managing patients with gastroparesis. Each chapter is written by experts in their respective area. The volume will enable the reader to better understand all aspects of this disorder. The book presents current concepts in a variety of areas opening with the epidemiology, clinical presentation and pathophysiology of gastroparesis. The natural history of patients is explored as well as evaluation of patients with suspected gastroparesis. This section includes chapters on Wireless Capsule Motility, Electrogastrography and Antroduodenal Manometry. This important resource concludes with a full section on treatment including dietary, prokinetic, antiemetic, sensory, electric stimulation, and surgical methods. New developments include the use of gastric electric stimulation for treatment, the use of SmartPill for diagnosis, and a number of new agents in development for this disorder. Gastroparesis: Pathophysiology, Presentation and Treatment is the ideal reference for gastroenterologists, and also for surgeons, endocrinologists, primary care physicians and nutritionists looking to keep pace with the latest information treatment options for their patients.
Author: Michael Barany
Publisher: Elsevier
ISBN: 0080527892
Category : Science
Languages : en
Pages : 455
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Book Description
This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.
Author: Jeffrey O. Hollinger
Publisher: CRC Press
ISBN: 143981256X
Category : Medical
Languages : en
Pages : 646
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Book Description
A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided into four sections (Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications), this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types. Unique in its inclusion of the practicalities of biomaterials as an industry, the book also covers the basic principles of statistics, new U.S. FDA information on the biomaterials-biology issues relevant to patent applications, and considerations of intellectual property and patent disclosure. With nine completely new chapters and 24 chapters extensively updated and revised with new accomplishments and contemporary data, this comprehensive introduction discusses 13 important classes of biomaterials, their fundamental and applied research, practical applications, performance properties, synthesis and testing, potential future applications, and commonly matched clinical applications. The authors include extensive references, to create a comprehensive, yet manageable didactic work that is an invaluable desk references and instructional text for undergraduates and working professionals alike.
Author: Y. C. Fung
Publisher: Springer Science & Business Media
ISBN: 1475717520
Category : Medical
Languages : en
Pages : 443
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Book Description
The motivation for writing aseries ofbooks on biomechanics is to bring this rapidly developing subject to students of bioengineering, physiology, and mechanics. In the last decade biomechanics has become a recognized disci pline offered in virtually all universities. Yet there is no adequate textbook for instruction; neither is there a treatise with sufficiently broad coverage. A few books bearing the title of biomechanics are too elementary, others are too specialized. I have long feIt a need for a set of books that will inform students of the physiological and medical applications of biomechanics, and at the same time develop their training in mechanics. We cannot assume that all students come to biomechanics already fully trained in fluid and solid mechanics; their knowledge in these subjects has to be developed as the course proceeds. The scheme adopted in the present series is as follows. First, some basic training in mechanics, to a level about equivalent to the first seven chapters of the author's A First Course in Continuum Mechanics (Prentice-Hall,lnc. 1977), is assumed. We then present some essential parts of biomechanics from the point of view of bioengineering, physiology, and medical applications. In the meantime, mechanics is developed through a sequence of problems and examples. The main text reads like physiology, while the exercises are planned like a mechanics textbook. The instructor may fil1 a dual role: teaching an essential branch of life science, and gradually developing the student's knowledge in mechanics.
Author: Jiro Nagatomi
Publisher: CRC Press
ISBN: 0429816731
Category : Medical
Languages : en
Pages : 927
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Book Description
Mechanobiology—the study of the effects of mechanics on biological events—has evolved to answer numerous research questions. Mechanobiology Handbook 2nd Edition is a reference book for engineers, scientists, and clinicians who are interested in mechanobiology and a textbook for senior undergraduate to graduate level students of this growing field. Readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluid mechanics, and molecular analysis techniques. The new edition presents, in addition to the chapters of the first edition, homework problem sets that are available online and reviews of research in uncovered areas. Moreover, the new edition includes chapters on statistical analysis, design of experiments and optical imaging. The editors of this book are researchers and educators in mechanobiology. They realized a need for a single volume to assist course instructors as a guide for didactic teaching of mechanobiology to a diverse student body. A mechanobiology course is frequently made up of both undergraduate and graduate students pursuing degrees in engineering, biology, or integrated engineering and biology. Their goal was to present both the elementary and cutting-edge aspects of mechanobiology in a manner that is accessible to students from many different academic levels and from various disciplinary backgrounds. Moreover, it is their hope that the readers of Mechanobiology Handbook 2nd Edition will find study questions at the end of each chapter useful for long-term learning and further discussion. Comprehensive collection of reviews of recent research Introductory materials in mechanics, biology, and statistics Discussion of pioneering and emerging mechanobiology concepts Presentation of cutting-edge mechanobiology research findings across various fields and organ systems End of chapter study questions, available online Considering the complexity of the mechanics and the biology of the human body, most of the world of mechanobiology remains to be studied. Since the field is still developing, the Mechanobiology Handbook raises many different viewpoints and approaches with the intention of stimulating further research endeavours.
Author:
Publisher:
ISBN:
Category : Mechanics, Applied
Languages : en
Pages : 700
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Book Description
Author: Valentin Fuster
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781735834
Category : Medical
Languages : en
Pages : 1700
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Book Description
Written by the world’s foremost authorities, this volume provides comprehensive coverage of current approaches to the prevention, diagnosis, and management of atherothrombosis and its coronary and noncoronary complications. This edition has been thoroughly updated, sharply focused on clinical information, and trimmed to one manageable volume. Coverage begins with a review of risk factors and prevention, emphasizing lipid abnormalities, hypertension, smoking, diabetes, and obesity. Subsequent sections examine the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, chronic stable angina, and noncoronary atherothrombosis. Clinical presentations, medical management, and the latest interventional strategies are included.
