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Author: T. Norman Palmer
Publisher: Springer Science & Business Media
ISBN: 1468459465
Category : Science
Languages : en
Pages : 359
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Book Description
This book contains selected proceedings from the NATO Advanced Study Institute (AS I) "The Molecular Pathology of Alcoholism" held at the Hotel Il Ciocco in Tuscany during 26th August - 6th September 1990. Alcoholism remains one of the most challenging problems in medical care, with far-reaching medical, social and economic consequences. For example in the U. S. , estimates indicate that 18 million people have a serious drinking problem and that the total cost to the economy of alcohol abuse is $117 billion. Treatment of alcohol dependence and other alcohol-related disorders accounts for almost 15% of the total health bill of the United States. Despite the scale of the medical problem, biomedical research on alcoholism remains something of a 'Cinderella science'. Research funding from government and other bodies is relatively poor and the number of medical scientists working in the field remains small. The Organizing Committee for this NATO ASI, comprising Charles Lieber (New York), Timothy Peters (London), Mario Dianzani (Torino), Emanuele Albano (Torino) and Norman Palmer (perth, Director), were therefore particularly grateful to the NATO Scientific Affairs Division for their active support of this AS I, the first dealing with a topic related to alcohol abuse. We moreover hope that this support will continue. The theme of the ASI was an in depth discussion of the molecular events initiated by alcohol abuse that culminate in onset of alcohol-related disease.
Author: T. Norman Palmer
Publisher: Springer Science & Business Media
ISBN: 1468459465
Category : Science
Languages : en
Pages : 359
Get Book Here
Book Description
This book contains selected proceedings from the NATO Advanced Study Institute (AS I) "The Molecular Pathology of Alcoholism" held at the Hotel Il Ciocco in Tuscany during 26th August - 6th September 1990. Alcoholism remains one of the most challenging problems in medical care, with far-reaching medical, social and economic consequences. For example in the U. S. , estimates indicate that 18 million people have a serious drinking problem and that the total cost to the economy of alcohol abuse is $117 billion. Treatment of alcohol dependence and other alcohol-related disorders accounts for almost 15% of the total health bill of the United States. Despite the scale of the medical problem, biomedical research on alcoholism remains something of a 'Cinderella science'. Research funding from government and other bodies is relatively poor and the number of medical scientists working in the field remains small. The Organizing Committee for this NATO ASI, comprising Charles Lieber (New York), Timothy Peters (London), Mario Dianzani (Torino), Emanuele Albano (Torino) and Norman Palmer (perth, Director), were therefore particularly grateful to the NATO Scientific Affairs Division for their active support of this AS I, the first dealing with a topic related to alcohol abuse. We moreover hope that this support will continue. The theme of the ASI was an in depth discussion of the molecular events initiated by alcohol abuse that culminate in onset of alcohol-related disease.
Author: Henri Begleiter
Publisher: Alcohol and Alcoholism
ISBN: 9780195088779
Category : Medical
Languages : en
Pages : 420
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Book Description
This volume provides an in-depth look at the genetic influences that contribute to the development of alcoholism. Part I: Epidemiologic Studies contains five chapters that examine the various approaches employed in the study of the genetics of alcoholism. It provides a historical perspective and details all the essentials of this subject. Part II: Selective Breeding Studies highlights the results of research involving the selective breeding of rodents. This type of research has produced homogenous strains exhibiting specific behavioral responses considered significant in the development and maintenance of alcohol dependence. The studies presented in Part III: Phenotypic Studies investigate and analyze phenotypic markers that serve as correlates to the genotypic determinants of alcoholism. Through its broad scope, this volume provides for the first time a panoramic view of the knowledge available on the hereditary influences of alcoholism.
Author: Rafael Maldonado
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 368
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Book Description
A comprehensive multidisciplinary review of the most relevant molecular, genetic, and behavioral approaches used to investigate the neurobiological basis of drug addiction. The authors explore the latest findings on opioid, psychostimulant, cannabinoid, alcohol, and nicotine addiction, provide fresh insights into the genetic basis of drug addiction and the new therapeutic perspectives these have opened. They describe the technology available to generate conditional knockout mice and show how these mice can reveal the molecular basis of opioid, psychostimulant, and cannabinoid addiction. They also review the different behavioral models available to evaluate the rewarding effects of drugs and analyze the genes involved in alcohol dependence.
Author: Edith V. Sullivan
Publisher: Elsevier
ISBN: 0444626220
Category : Science
Languages : en
Pages : 703
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Book Description
Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. - The first focused reference specifically on alcohol and the brain - Details our current understanding of how alcohol impacts the central nervous system - Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse - Includes section on neuroimaging of neurochemical markers and brain function
Author: Kenneth Blum
Publisher: Springer Science & Business Media
ISBN: 146147230X
Category : Medical
Languages : en
Pages : 98
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Book Description
Humans are biologically programmed to seek out pleasurable experiences. These experiences are processed in the mesolimbic system, also referred to as the "reward center" of the brain, where a number of chemical messengers work in concert to provide a net release of dopamine in the Nucleus Accumbens. In some genetically predisposed individuals, addiction occurs when the mechanisms of the mesolimbic system are disrupted by the use of various drugs of abuse. Since Alcoholics Anonymous was founded in 1935, it's 12 step program of spiritual and character development has helped countless alcoholics and drug addicts curb their self-destructive behaviors. However, the program was developed at a time when comparatively little was known about the function of the brain and it has never been studied scientifically. This is the first book to take a systematic look at the molecular neurobiology associated with each of the 12 steps and to review the significant body of addiction research literature that is pertinent to the program.
Author:
Publisher:
ISBN: 0190275332
Category :
Languages : en
Pages : 577
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Book Description
Author: Michael T. Windle
Publisher: Guilford Publication
ISBN: 9780898621686
Category : Psychology
Languages : en
Pages : 244
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Book Description
Children of alcoholics (COAs) are thought to be at heightened risk for the development of alcoholism. Yet, despite the recent spate of articles in both the professional literature and the popular press on the effects of having alcoholic parents, there remains much controversy surrounding the topic. Offering a state-of-the-art review of the literature and a critical evaluation of COA research, chapters in this volume analyze such key areas as: * The prevalence of alcoholism and other forms of maladjustment among COAs * The role of biological and environmental factors in the expression of alcoholism * Optimal ways of intervening to prevent or ameliorate harmful consequences associated with being the offspring of an alcoholic. With the widespread interest in COAs and their functioning across the life span, this volume serves as an invaluable resource for clinicians, alcohol researchers, developmentalists, school counselors, nurses, medical doctors, and educators.
Author: Shafiqur Rahman
Publisher: Academic Press
ISBN: 0128038683
Category : Psychology
Languages : en
Pages : 279
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Book Description
This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction. - Contains contributions from leading authorities - Informs and updates on all the latest developments in the field
Author: Lorraine Midanik
Publisher: Routledge
ISBN: 1351327828
Category : Psychology
Languages : en
Pages : 192
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Book Description
Biomedicalization is seen as the natural outgrowth of continued scientific progress--a movement towards improving the quality and quantity of life through scientific inquiries using biomedical perspectives and methods. This approach carries with it the assumption that with "proper" risk assessment, detection, and treatment, our lives can be lengthened, improved, and indeed more fulfilling. Yet critics question biomedicalization's ability to deliver. There is concern about how biomedicalization can change our traditional concepts of health as we discover more conditions for which we are at risk, and health maintenance is seen as the responsibility of the individual. The purpose of the book is to describe, assess, and critique biomedicalization and its influence as a larger social trend on the health field and specifically in the area of alcohol research, policy, and programs. Chapter 1 gives a broad overview of biomedicalization. Chapter 2 lays the groundwork for a historical understanding of how medicalization and biomeidcalization have developed and are expressed in diverse fields such as aging, psychiatry/mental health, and women's health. Chapter 3 focuses in-depth on alcoholism and assesses the development and assumptions underlying the two movements that have greatly influenced the substance abuse field: the medicalization of deviance and the growth of the disease model of alcoholism. Chapter 4 discusses the origins and development of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) from its inception in 1970. Chapter 5 illustrates the growing biomedicalization that has occurred in the alcohol field prior to NIAAA's movement to the National Institute of Health (NIH). Chapter 6 assesses how Sweden has handled alcohol problems and currently funds alcohol research. Chapter 7 concludes with a rationale for an expanded discourse between social scientists and biomedical researchers working on social problems, particularly alcohol issues. This volume will stimulate discussion of the processes by which social problems, and specifically alcohol issues, are framed, managed, and studied. It will hold particular interest for researchers and students in the areas of alcohol studies, social science, and social welfare. Lorraine Midanik is a professor in the School of Social Welfare, University of California, Berkeley.
Author: W.W. Fleischhacker
Publisher: Springer Science & Business Media
ISBN: 9783211013151
Category : Medical
Languages : en
Pages : 136
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Book Description
Substance-related disorders pose an increasing challenge not only to the field of psychiatry but also to public health. The rapid development of our society has also changed the face of substance use and abuse, both quantitatively and qualitatively. In this volume international experts present reviews of the latest research covering many areas ranging from neurobiology to psychological management, as well as different drugs, from alcohol to ecstasy.
