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Author: Deepak Kumar Kaushik
Publisher: Frontiers Media SA
ISBN: 2889714748
Category : Science
Languages : en
Pages : 187
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Book Description
Author: Deepak Kumar Kaushik
Publisher: Frontiers Media SA
ISBN: 2889714748
Category : Science
Languages : en
Pages : 187
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Book Description
Author: Agnieszka J. Szczepek
Publisher: Frontiers Media SA
ISBN: 2889665909
Category : Medical
Languages : en
Pages : 231
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Book Description
Author: Mark Slevin
Publisher: Frontiers Media SA
ISBN: 2889457230
Category :
Languages : en
Pages : 182
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Book Description
Over recent years, native pentameric C-reactive protein (pCRP) and its biologically active dissociated form, monomer monomeric CRP (mCRP) have assumed an important role in disease development and pathophysiology. In this series, we have highlighted the thoughts and research of the most eminent scientists in the field of CRP research. This eBook is a collection of original articles and reviews on the subject, creating an archive of current knowledge and understanding. This Research Topic provides new findings of the role of CRP in the fields of neuroscience, cardiovascular disease, inflammation, and macular degeneration as well as defined links to stages in pathological disease progression. These articles explain the mechanisms and pathways through which the dissociated mCRP interacts with a variety of cells, and provide possible prognostic implications and new methods for analysis. Over the coming years, the importance and fascination of the active role of CRP in health and disease is set to rise, and we hope this collection will serve as a valuable reference for these future investigations.
Author:
Publisher: Elsevier
ISBN: 0444634460
Category : Medical
Languages : en
Pages : 569
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Book Description
Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. - Includes comprehensive coverage of autoimmune neurology - Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders - Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities
Author: Karl Bechter
Publisher: Frontiers Media SA
ISBN: 2889459500
Category :
Languages : en
Pages : 189
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Book Description
Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms may contribute to a subset of patients currently diagnosed as having treatment-resistant SMDs such as schizophrenia and major depressive disorder. Additionally, mounting data indicate that various infections can serve as an immunological trigger of aberrant immune responses, presumably by causing release of excess neural antigen, thereby giving rise to NSAs or aberrant immune cellular responses to give rise to primary or secondary psychiatric disorders such as schizophrenia and those associated with AE, respectively. Collectively, these findings support the “mild encephalitis” hypothesis of SMD. The significant overlap among AE-associated psychosis, systemic autoimmune disorder-associated psychosis, and psychotic disorders associated with pathological processes involving inflammation and immune dysregulation has also prompted some authors to adopt the term “autoimmune psychosis” (AP). This term reflects that this psychosis subtype is mechanistically linked to complex neuroimmune and inflammatory signalling abnormalities that can be responsive to early immunomodulatory treatment. It also suggests that a subset of AP might represent an incomplete or “forme fruste” subtype of AE presenting with dominant or pure psychiatric symptoms mimicking primary psychiatric illnesses. Because data indicate that delayed diagnosis and treatment may lead to permanent sequelae, early recognition of AP utilizing neurodiagnostic workup (e.g., CSF analysis, neuroimaging, and EEG) and its early treatment with appropriate immunotherapy are paramount to a meaningful recovery. This eBook will provide an overview of the current knowledge and research areas from epidemiology, risk factors and diagnosis to the management of these conditions, in this rapidly emerging field, helping to bridge the gaps in knowledge that currently exist in the disciplines of Psychiatry, Neurology, and Neuroimmunology.
Author: D. Platt
Publisher: Springer Science & Business Media
ISBN: 3642682146
Category : Medical
Languages : en
Pages : 502
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Book Description
In 1909 a short contribution entitled "Geriatrics" was published in the New York Medical Journal. According to this article, old age represents a distinct period oflife in which the physiologic changes caused by aging are accompanied by an increasing number of pathologic changes. We now know that the organs of the body age neither at the same rate nor to the same extent and that physiologic alterations are indeed superimposed by pathologic changes; as a result of the latter phenomenon the origins and course of illnesses in the elderly can present unusual characteristics. The frequency of concurrent disorders in the elderly entails the danger of polypragmatic pharmacotherapy, i. e. , the use of various drugs to combat various disorders while neglecting the possibly adverse combined effects of these drugs. To obviate this danger, special knowledge in the field of geriatrics, the medical branch of gerontology, is necessary. Geriatrics is constantly increasing in importance owing to the near doubling of life expectancy over the past 130 years and to the improved diagnostic and therapeutic techniques made available by medical pro gress. The rapid recent development of experimental gerontology has played an essential role in enabling us to understand the special features of geriatrics. This progress has, however, been accompanied by such a vast increase in the volume of literature on the subject that specialists in the field can scarcely maintain an overall perspective of new publications.
Author: Donna Gruol
Publisher: MDPI
ISBN: 3038425702
Category : Medical
Languages : en
Pages : 161
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Book Description
This book is a printed edition of the Special Issue "Advances in Neuroimmunology" that was published in Brain Sciences
Author:
Publisher: Elsevier
ISBN: 0323859445
Category : Science
Languages : en
Pages : 380
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Book Description
Circadian and Visual Neuroscience, Volume 273 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on topics including Optical set-ups, Psychophysics of Luminance and Color Vision, Psychophysics of non-visual photoreception PRC/IRC/DRC/Spectral Sensitivity, Circadian and visual photometry, Modelling (retina), Modelling (circadian), Techniques for examining vision at the cellular level, Advanced techniques for characterizing the world hyperspectrally, Circadian physiology in mice: Melanopsin, Circadian physiology in mice: Color and cones, Translational aspects of animal studies, Retinal clocks, Primate non-visual physiology, Light and mood in animal models, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Progress in Brain Research series - Updated release includes the latest information on Circadian and Visual Neuroscience
Author: Masaki Ieda
Publisher: Springer
ISBN: 3319561065
Category : Medical
Languages : en
Pages : 277
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Book Description
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Author: Bibiana Bielekova MD
Publisher: Oxford University Press
ISBN: 0190050829
Category : Medical
Languages : en
Pages : 329
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Book Description
Neuroimmunology, the latest volume in the Contemporary Neurology Series, provides a practical, clinical, and scientific background on a diverse group of neurological disorders in this rapidly expanding field. The book includes chapters on multiple sclerosis and related disorders in adults and children, neuromyelitis optica spectrum disorder, Guillain-Barre Syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and variants, immune-mediated disorders of the neuromuscular junction, inflammatory myopathies, paraneoplastic disorders and autoimmune encephalitities, and neurologic manifestations of systemic immune-mediated diseases. Unique to the work, the authors have included an introductory chapter on the basics of immunology and another on mechanisms of action of therapies used in neuroimmunologic disorders. The clinical chapters cover epidemiology, pathology, pathogenesis, and pathophysiology of the different diseases along with clinical presentation, diagnostic testing, differential diagnosis, and treatment. All are presented in an accessible, practical format, making this volume a valuable resource for physicians and other healthcare providers that will care for persons with neuroimmunologic diseases.
