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Author: Fabio Arturo Iannotti
Publisher: Intechopen
ISBN: 9781803562728
Category :
Languages : en
Pages : 0
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Book Description
Skeletal muscles are the vastest tissue in the human body with an essential role in maintaining posture, moving, and regulating internal body temperature and metabolism. Consequently, skeletal muscle injuries or diseases can have a profound effect on one's life. In Advances in Skeletal Muscle Health and Disease, Fabio Arturo Iannotti has assembled contributions from international experts to provide a conclusive guide to what continues to be a rapidly developing research field. After a short introductory chapter, the book continues by looking at the biochemical, genetic, and molecular elements and mechanisms underlying skeletal muscle health and disease.
Author: Fabio Arturo Iannotti
Publisher: Intechopen
ISBN: 9781803562728
Category :
Languages : en
Pages : 0
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Book Description
Skeletal muscles are the vastest tissue in the human body with an essential role in maintaining posture, moving, and regulating internal body temperature and metabolism. Consequently, skeletal muscle injuries or diseases can have a profound effect on one's life. In Advances in Skeletal Muscle Health and Disease, Fabio Arturo Iannotti has assembled contributions from international experts to provide a conclusive guide to what continues to be a rapidly developing research field. After a short introductory chapter, the book continues by looking at the biochemical, genetic, and molecular elements and mechanisms underlying skeletal muscle health and disease.
Author: Mani T. Valarmathi
Publisher: BoD – Books on Demand
ISBN: 1789239672
Category : Science
Languages : en
Pages : 182
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Book Description
The three different types of muscle tissue found in the animal kingdom are cardiac, skeletal, and smooth. The muscle cells are not only complex but also fascinating. In recent years there has been substantial advances in our understanding of muscle cell biology, especially in areas of molecular anatomy, basic physiology, understanding disease mechanisms, and therapeutic targets. Consequently, this book mainly focuses not only on the biology of myocytes, but also on all-encompassing disciplines pertaining to muscle tissue, such as fundamental physiology, molecular mechanisms of diseases, muscle regeneration, etc. for all three types of muscle, namely, skeletal, cardiac, and smooth muscle. As a result, the goal of this book is to consolidate the recent advances in the area of muscle biology/diseases/regeneration covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in muscle cell biology, exercise physiology/science, stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough knowledge pertaining to recent advances in muscle biology in the context of health and disease.
Author: Roberto Bottinelli
Publisher: Springer Science & Business Media
ISBN: 1402051778
Category : Medical
Languages : en
Pages : 372
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Book Description
The ability of striated muscle tissue to adapt to changes in activity or in working conditions is extremely high. In some ways it is comparable to the ability of the brain to learn. The interest in muscle adaptation is increasing in relation to the idea that physical fitness helps in the prevention of disease, may counteract the loss of physical performance and generally improves wellbeing. Plasticity is the word used since the late 1970’s to indicate collectively all the processes and mechanisms which form the background of muscle adaptation. This book aims to provide a systematic updating of the available knowledge on molecular and cellular mechanisms, as well as on changes at whole muscle level. The book means to be a guide and a help for people who enter the field as PhD or medical students, but is also a tool for refreshing and updating knowledge for people already active in the field in basic sciences as well as in applied disciplines such as neurology, sports science and rehabilitation.
Author: Gilles Gouspillou
Publisher: Frontiers Media SA
ISBN: 2889450732
Category : Electronic book
Languages : en
Pages : 144
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Book Description
Skeletal muscle is the most abudant tissue of the human body, making up to 40 to 50% of the human body mass. While the importance of optimal muscle function is well recognized in the athletic field, its significance for general health is often underappreciated. In fact, the evidence that muscle mass, strength and metabolism are essential for our overall health is overwhelming. As the largest protein reservoir in the human body, muscles are essential in the acute response to critical illness such as sepsis, advanced cancer, and traumatic injury. Loss of skeletal muscle mass has also been associated with weakness, fatigue, insulin resistance, falls, fractures, frailty, disability, several chronic diseases and death. As a consequence, maintaining skeletal muscle mass, strength and metabolism throughout the lifespan is critical to the maintenance of whole body health. Mitochondria are fascinating organelles regulating many critical cellular processes for skeletal muscle physiology, including for instance energy supply, reactive oxygen species production, calcium homeostasis and the regulation of apoptosis. It is therefore not surprising that mitochondrial dysfunction has been implicated in a large number of adverse events/conditions and pathologies affecting skeletal muscle health. While the importance of normal mitochondrial function is well recognized for muscle physiology, there are important aspects of mitochondrial biology that are still poorly understood. These include mitochondrial dynamics (fusion and fission processes), morphology and processes involved in mitochondrial quality control (mitophagy). Defining the mechanisms regulating these different aspects of mitochondrial biology, their importance for muscle physiology, as well as the interrelations will be critical for expanding understanding of the role played by mitochondria in skeletal muscle physiology and health. The present research topic provides readers with novel experimental approaches, knowledge, hypotheses and findings related to all aspects of mitochondrial biology in healthy and diseased muscle cells.
Author: Mark Willems
Publisher: Nova Science Publishers
ISBN: 9781624172717
Category : Muscles
Languages : en
Pages : 0
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Book Description
It is essential for our quality of life to have healthy muscles. Tragically, the loss of even a single protein can have dramatic effects on muscle functioning and quality of life. This book is about skeletal muscles, their physiological complexity and molecular functioning in health and disease. The range of topics varies from the fascinating events at the level of the cross-bridges, the aging process of skeletal muscles, ischemia-reperfusion, inflammatory myopathies and mitochondrial function, muscular dystrophy and the regulation of skeletal muscle mass in health and disease. This book is written by internationally acclaimed researchers and expert research groups and provides state of the art understanding of the plasticity of skeletal muscle, information that is vital for health professionals who deal with diverse chronic disease conditions.
Author: Mark Willems
Publisher: Nova Science Publishers
ISBN: 9781624172861
Category : Science
Languages : en
Pages : 235
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Book Description
It is essential for our quality of life to have healthy muscles. Tragically, the loss of even a single protein can have dramatic effects on muscle functioning and quality of life. This book is about skeletal muscles, their physiological complexity and molecular functioning in health and disease. The range of topics varies from the fascinating events at the level of the cross-bridges, the aging process of skeletal muscles, ischemia-reperfusion, inflammatory myopathies and mitochondrial function, muscular dystrophy and the regulation of skeletal muscle mass in health and disease. This book is written by internationally acclaimed researchers and expert research groups and provides state of the art understanding of the plasticity of skeletal muscle, information that is vital for health professionals who deal with diverse chronic disease conditions.
Author: Ronald J. Korthuis
Publisher: Morgan & Claypool Publishers
ISBN: 1615041834
Category : Medical
Languages : en
Pages : 147
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Book Description
The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References
Author: Céline Aguer
Publisher: Frontiers Media SA
ISBN: 288966130X
Category : Science
Languages : en
Pages : 140
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Alexander Mauro
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 582
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Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309670950
Category : Medical
Languages : en
Pages : 319
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Book Description
The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.
